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5301“…We examined the combinatory effects of Rho-associated kinase (ROCK) inhibitor Y-27632 and mesenchymal stem cell-derived conditioned medium (MSC-CM) on the proliferation and senescence of rabbit corneal endothelial cells (rCECs). rCECs were cultured in a control medium, a control medium mixed with either Y-27632 or MSC-CM, and a combinatory medium containing Y-27632 and MSC-CM. …”
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5302“…High concentrations of UA also up-regulated Rho-kinase expression and mitochondrial and apoptosis-related protein expression, while treatment with fasudil and ROCK1 si-RNA significantly attenuated these responses. …”
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5303por Marlow, Jeffrey J., Hoer, Daniel, Jungbluth, Sean P., Reynard, Linda M., Gartman, Amy, Chavez, Marko S., El-Naggar, Mohamed Y., Tuross, Noreen, Orphan, Victoria J., Girguis, Peter R.“…Here, we conducted a continental-scale survey of seven geologically diverse seafloor seeps and found that carbonate rocks from all sites host methane-oxidizing microbial communities with substantial methanotrophic potential. …”
Publicado 2021
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5304“…Soil and mosses were collected from sites representing different stages of ecological restoration (bare rock, grassland, shrubland, and secondary forest), and the contents of carbon (C), nitrogen (N), and phosphorus (P) were detected for ecological stoichiometric analysis. …”
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5305“…To characterize the level of resistance these mutations confer, we isolated a pyrethroid resistant strain (LMRKDR:RK, LKR) that was congenic to the susceptible Rockefeller (ROCK) strain. The full-length cDNA of Vssc was cloned from LKR and no additional resistance mutations were present. …”
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5306por Györfi, Andrea-Hermina, Matei, Alexandru-Emil, Fuchs, Maximilian, Liang, Chunguang, Rigau, Aleix Rius, Hong, Xuezhi, Zhu, Honglin, Luber, Markus, Bergmann, Christina, Dees, Clara, Ludolph, Ingo, Horch, Raymund E., Distler, Oliver, Wang, Jiucun, Bengsch, Bertram, Schett, Georg, Kunz, Meik, Distler, Jörg H.W.“…Functional experiments confirm the coordinating role of EN1 on ROCK activity and the reorganization of cytoskeleton during myofibroblast differentiation, in both standard fibroblast culture systems and in vitro skin models. …”
Publicado 2021
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5307por Nolte, Tanja, Jansen, Simon, Weigend, Steffen, Moerlein, Daniel, Halle, Ingrid, Simianer, Henner, Sharifi, Ahmad Reza“…The tested chicken genotypes were two local breeds, the Vorwerkhuhn and the Bresse Gauloise, as well as the commercial line White Rock and crossbreds thereof. The genotype had an influence on yolk weight, Haugh units, yolk and shell color, the frequency of inclusions in the eggs and the composition of the eggs. …”
Publicado 2021
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5308por Hupfeld, Julia, Ernst, Maximilian, Knyrim, Maria, Binas, Stephanie, Kloeckner, Udo, Rabe, Sindy, Quarch, Katja, Misiak, Danny, Fuszard, Matthew, Grossmann, Claudia, Gekle, Michael, Schreier, Barbara“…We identified 40 potential targets by comparison to miR-walk 2.0 3′-UTR, 5′-UTR and CDS targets. Among those targets, Rock2 and Ran were upregulated in Western blots of HL-1 cells by miR-208b mimics. …”
Publicado 2021
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5309“…To explore the influence of solid residue after pyrolysis of oil shale on the groundwater environment, we performed ultrapure water–rock interaction experiments. The results showed that Pb tended to accumulate in solid residues during pyrolysis. …”
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5310por Xiang, Yuzhou, Zeng, Zhikai, Xiang, Yangjun, Abi, Erdi, Zheng, Yingren, Yuan, Hechuan“…The overall stability, the integrity of rock mass, and the failure pattern transition under loading and unloading processes were systematically examined. …”
Publicado 2021
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5311por Scheller, Eva L., Swindle, Carl, Grotzinger, John, Barnhart, Holly, Bhattacharjee, Surjyendu, Ehlmann, Bethany L., Farley, Ken, Fischer, Woodward W., Greenberger, Rebecca, Ingalls, Miquela, Martin, Peter E., Osorio-Rodriguez, Daniela, Smith, Ben P.“…Magnesium carbonates form in five distinct settings: ultramafic rock-hosted veins, the matrix of carbonated peridotite, nodules in soil, alkaline lake, and playa deposits, and as diagenetic replacements within lime—and dolostones. …”
Publicado 2021
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5312por Zou, Yuan‐Jing, Shan, Meng‐Meng, Wang, Hong‐Hui, Pan, Zhen‐Nan, Pan, Meng‐Hao, Xu, Yi, Ju, Jia‐Qian, Sun, Shao‐Chen“…CONCLUSIONS: Taken together, our results suggest that RAB14 affects ROCK‐cofilin pathway for actin‐based spindle migration and Golgi apparatus distribution during mouse oocyte meiotic maturation.…”
Publicado 2021
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5313“…Additionally, astrocytic differentiation of embryonic NSCs was induced by a Ras homolog associated kinase (ROCK) inhibitor, which decreased PP-MRLC in NSCs. …”
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5314por Tognoli, Maria Laura, Vlahov, Nikola, Steenbeek, Sander, Grawenda, Anna M, Eyres, Michael, Cano‐Rodriguez, David, Scrace, Simon, Kartsonaki, Christiana, von Kriegsheim, Alex, Willms, Eduard, Wood, Matthew J, Rots, Marianne G, van Rheenen, Jacco, O'Neill, Eric, Pankova, Daniela“…Cell plasticity is a crucial hallmark leading to cancer metastasis. Upregulation of Rho/ROCK pathway drives actomyosin contractility, protrusive forces, and contributes to the occurrence of highly invasive amoeboid cells in tumors. …”
Publicado 2021
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5315por Dugamin, Elza J. M., Richard, Antonin, Cathelineau, Michel, Boiron, Marie-Christine, Despinois, Frank, Brisset, Anne“…However, conventional hard-rock and salar mining are facing environmental and social concerns. …”
Publicado 2021
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5316por Hsiao, Hong-Chin“…Education is the stable rock of ethics and morality, and like the foundation upon which to build a house, an unstable rock would result in the danger of collapse. …”
Publicado 2021
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5317por Llamas-Granda, Patricia, Martin-Rodríguez, Laura, Largo, Raquel, Herrero-Beaumont, Gabriel, Mediero, Aránzazu“…Primary murine-induced osteoclast/osteoblast were challenged with tenofovir/dipyridamole 1 μM each, and the expression of Sema4D/PlexinB1, RhoA/ROCK/IGF1R was studied by RT-PCR, Western blot and immunostaining. …”
Publicado 2021
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5318“…The exceptions were the NR activity, which was active only in the Ap horizon and whose activity decreased sharply to nearly zero in the Bt horizon and parent rock, and the PHA activity, which was highly active even in the parent rock depth. …”
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5319“…Exoplanets with a high refractory oxygen abundance exhibit more extensive and longer duration magmatic activity, leading to more efficient and more massive volcanic outgassing of more oxidized gas species than comparable exoplanets with a lower rock fO(2).…”
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5320“…Thus, it is difficult to distinguish the adsorbed and free gas in the coal and rock and accurately calculate the CO(2)/CH(4) replacement ratio in the displacement process. …”
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