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5401por Larrasoaña, Juan C., Liu, Qingsong, Hu, Pengxiang, Roberts, Andrew P., Mata, Pilar, Civis, Jorge, Sierro, Francisco J., Pérez-Asensio, José N.“…We present a paleo- and rock-magnetic study of late Miocene marine sediments recovered from the Guadalquivir Basin (SW Spain). …”
Publicado 2014
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5402por Olivier, Jocelien D. A., Åkerud, Helena, Skalkidou, Alkistis, Kaihola, Helena, Sundström-Poromaa, Inger“…Among the genes that were validated ROCK2 and C12orf39 were differentially expressed in both depressed and antidepressant-treated women, whereas ROCK1, GCC2, KTN1, and DNM1L were only differentially expressed in the antidepressant-treated women. …”
Publicado 2015
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5403por Armstrong, Ryan T, Ott, Holger, Georgiadis, Apostolos, Rücker, Maja, Schwing, Alex, Berg, Steffen“…With recent advances at X-ray microcomputed tomography (μCT) synchrotron beam lines, it is now possible to study pore-scale flow in porous rock under dynamic flow conditions. The collection of four-dimensional data allows for the direct 3-D visualization of fluid-fluid displacement in porous rock as a function of time. …”
Publicado 2014
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5404por DENG, MINGHONG, LUO, YUMEI, LI, YUNKUI, YANG, QIUCHEN, DENG, XIAOQIN, WU, PING, MA, HOUXUN“…In addition, rAAV.mKL decreased the protein expression levels of fibronectin and vimentin, while it downregulated the mRNA expression and activity of Rho-associated coiled-coil kinase (ROCK)I in the kidneys of the diabetic rats. These results indicated that klotho gene delivery ameliorated renal hypertrophy and fibrosis in diabetic rats, possibly by suppressing the ROCK signaling pathway. …”
Publicado 2015
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5405por Milioli, Heloisa Helena, Vimieiro, Renato, Riveros, Carlos, Tishchenko, Inna, Berretta, Regina, Moscato, Pablo“…The new subtypes show accurate distributions of current clinical markers ER, PR and HER2, and survival curves in the METABRIC and ROCK data sets. Remarkably, the paradoxical attribution of the original labels reinforces the limitations of employing a single sample classifiers to predict breast cancer intrinsic subtypes.…”
Publicado 2015
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5406“…These charge carriers are able to flow out of the stressed rock volume into surrounding rocks. Such outflow constitutes an electric current, which generates electromagnetic (EM) signals. …”
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5407“…For each quadrat, the substrate was classified as sand, sand-cobble mix, cobble, coarse, or rock, and water depth and distance from bank were measured. …”
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5408por Mikami, Taro, Yoshida, Keiichiro, Sawada, Hajime, Esaki, Michiyo, Yasumura, Kazunori, Ono, Michio“…The leading edge of cells in the cell sheet formed a simple layer and moved forward regularly; these rows were followed by the stratified epithelium. ROCK inhibitors and ROCK small interfering RNAs (siRNAs) disturbed not only the collective migration of the leading edge of this cell sheet, but also the stratified layer in the rear. …”
Publicado 2015
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5409“…This is equivalent to the absence of weak priority effects, protected dimorphisms and rock–scissor–paper configurations. Our concept differs from that of Heino et al. …”
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5410por Lee, Mei-Yueh, Tsai, Kun-Bow, Hsu, Jong-Hau, Shin, Shyi-Jang, Wu, Jiunn-Ren, Yeh, Jwu-Lai“…Protein expression of ROCK II was increased while eNOS, sGC and PKG were decreased. …”
Publicado 2016
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5411por Wang, Yan, Liu, Qian, Xu, Yingqiong, Zhang, Yuanyuan, Lv, Yanni, Tan, Yisha, Jiang, Nan, Cao, Guosheng, Ma, Xiaonan, Wang, Jingrong, Cao, Zhengyu, Yu, Boyang, Kou, Junping“…These effects were mediated via the down-regulation of caspase-3, ROCK1 (Rho-associated kinase1) activation and myosin light chain (MLC, Ser-19) phosphorylation. …”
Publicado 2016
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5412por Davis, Christopher Sean“…Once there, they painted rock art on the landscape, which bears a record of the sun's horizon positions throughout the year. …”
Publicado 2016
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5413por Cui, Kai, Luan, Yang, Wang, Tao, Zhuan, Li, Rao, Ke, Wang, Shao-Gang, Ye, Zhang-Qun, Liu, Ji-Hong, Wang, Dao-Wen“…Taken together, these results indicated that the RhoA/ROCK1/LIMK/cofilin pathway may be involved in the corporal fibrosis caused by advanced age, and hKLK1 may reduce this corporal fibrosis by inhibiting the activation of this pathway to ameliorate age-related ED.…”
Publicado 2017
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5414“…We examined variation in subsurface thermal conditions of microrefuge habitats among different rock substrate types used by the American pika (Ochotona princeps), a climate‐sensitive, rock‐dwelling Lagomorph. …”
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5415por Wang, Yan, Xu, Yingqiong, Liu, Qian, Zhang, Yuanyuan, Gao, Zhen, Yin, Mingzhu, Jiang, Nan, Cao, Guosheng, Yu, Boyang, Cao, Zhengyu, Kou, Junping“…We further demonstrate that caspase-3/Rho-associated kinase 1 (ROCK1) dependent phosphorylation of myosin light chain (MLC) was required for the formation of the myosin IIA-actin complex. …”
Publicado 2017
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5416por Gardiner, Nicholas J., Hawkesworth, Chris J., Robb, Laurence J., Whitehouse, Martin J., Roberts, Nick M. W., Kirkland, Christopher L., Evans, Noreen J.“…Variations in zircon Hf and U/Yb reaffirm that tin belt magmas contain greater crustal contributions than copper arc rocks. Links between whole-rock Rb/Sr and zircon Eu/Eu* highlight that the latter can monitor magma fractionation in these systems. …”
Publicado 2017
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5417por Chen, Yun, Niu, Shuai, Li, Peikun, Jia, Hongru, Wang, Hailiang, Ye, Yongzhong, Yuan, Zhiliang“…Topography, forest, substrates (ground, tree trunks, roots, rocks, and rotten wood), and spatial factor, which factors are the major drivers of bryophyte distribution? …”
Publicado 2017
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5418“…Fasudil and SC may regulate the CNS by affecting the expression of neurite growth inhibitory factors in the RhoA/ROCK signaling pathway.…”
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5419por Korostylev, Alexander, Mahaddalkar, Pallavi U., Keminer, Oliver, Hadian, Kamyar, Schorpp, Kenji, Gribbon, Philip, Lickert, Heiko“…DE induced by the ROCK inhibitor Fasudil efficiently gives rise to PDX1(+) pancreatic progenitors from hESCs. …”
Publicado 2017
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5420“…It would have been a mud, rather than a rock. We tested the effect of removing the assumption of lithification. …”
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