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  1. 5561
    “…In addition to PB dispersion, KapB-mediated RhoA activation in primary ECs caused actin stress fiber formation, increased cell motility and angiogenesis; these effects were dependent on the activity of the RhoA substrate kinases ROCK1/2. By contrast, KapB-mediated PB dispersion occurred in a ROCK1/2-independent manner. …”
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    Viral Activation of MK2-hsp27-p115RhoGEF-RhoA Signaling Axis Causes Cytoskeletal Rearrangements, P-body Disruption and ARE-mRNA Stabilization
  2. 5562
    “…PET/CT scans were performed in four Formosan rock monkeys (two males and two females, each monkey scanned twice) using a Siemens BIOGRAPH scanner. …”
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    Toxicity and radiation dosimetry studies of the serotonin transporter radioligand [(18) F]AFM in rats and monkeys
  3. 5563
    “…The genes RSPO1, DAX1, SOX3, ROCK, DMRT1, SPRY2 and FGF9 were also assessed using sequencing analysis. …”
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    A duplication upstream of SOX9 was not positively correlated with the SRY-negative 46,XX testicular disorder of sex development: A case report and literature review
  4. 5564
    “…This increases the oil–gas contact and sweep efficiency, although adsorption of surfactant on rock surface can causes difficulties and increases costs of process. …”
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    Comparison of oil removal in surfactant alternating gas with water alternating gas, water flooding and gas flooding in secondary oil recovery process
  5. 5565
    “…Risk of nest failure was negatively associated with greater rock and more medium-sized gaps between shrubs (gap size ≥2.0 m and <3.0 m). …”
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    Microhabitat Conditions in Wyoming’s Sage-Grouse Core Areas: Effects on Nest Site Selection and Success
  6. 5566
    por Nakashima, Yoshiki, Omasa, Takeshi
    Publicado 2016
    “…In hiPSCs, the interaction of laminin-511/α6β1 integrin with the cell–cell adhesion molecule E-cadherin confers protection against apoptosis through the Ras homolog gene family member A (RhoA)/Rho kinase (ROCK) signaling pathway (the major pathways for cell death) and the proto-oncogene tyrosine-protein kinase Fyn (Fyn)-RhoA-ROCK signaling pathway. …”
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    What Kind of Signaling Maintains Pluripotency and Viability in Human-Induced Pluripotent Stem Cells Cultured on Laminin-511 with Serum-Free Medium?
  7. 5567
    “…In 2015, we conducted our annual Sex, Drugs and Rock’n’Roll study, an online health survey of over 1000 Victorians aged 15–29 years. …”
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    “I am yet to encounter any survey that actually reflects my life”: a qualitative study of inclusivity in sexual health research
  8. 5568
    “…Western blot analysis showed that (Fasudil)ST21-H(3)R(5)-PEG(miR195) had strong silencing activity of ROCK2 and VEGF, as compared with (Fasudil)H(3)R(5)-PEG(miR195). …”
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    Aptamer-functionalized peptide H(3)CR(5)C as a novel nanovehicle for codelivery of fasudil and miRNA-195 targeting hepatocellular carcinoma
  9. 5569
    “…In contrast, 5 weekly knockdowns with p120-Kaiso siRNAs since Day 7 precluded senescence mediated by p16(INK4a) by inducing nuclear translocation of Bmi1 because of sustained activation of JAK2-STAT3 signaling downstream of p120-Kaiso-RhoA-ROCK signaling. STAT3 or Bmi1 siRNA impeded nuclear exclusion of p16(INK4a) and suppressed the reprogramming induced by p120-Kaiso siRNAs, suggesting that another important engineering strategy of HCEC lies in prevention of senescence mediated by nuclear translocation of p16(INK4a).…”
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    Senescence Mediated by p16(INK4a) Impedes Reprogramming of Human Corneal Endothelial Cells into Neural Crest Progenitors
  10. 5570
    “…Small-bodied species have more restricted ranges than large-bodied species, and rock-dwelling species have more restricted ranges than either terrestrial or generalist species. …”
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    The measure of success: geographic isolation promotes diversification in Pachydactylus geckos
  11. 5571
    “…Experiments involving specific inhibitors demonstrated that the differential expression of cofilin‐1 (COFL1) and profilin‐1 (PROF1) during erinacine A treatment could be involved in the mechanisms of HCT‐116 and DLD‐1 cells death and decreased aggressiveness, which occurred via ROCK1/LIMK2/Cofilin expression, with activation of the PI3K/mTOR/p70S6K signalling pathway. …”
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    A proteomics approach to identifying novel protein targets involved in erinacine A–mediated inhibition of colorectal cancer cells’ aggressiveness
  12. 5572
    “…We determine that GIT2 is targeted to FAs in response to Rho-ROCK signaling and actomyosin contractility. Accordingly, inhibition of ROCK activity or MLC function promotes enrichment of DOCK5 in membrane protrusions and nascent cell–substratum adhesions. …”
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    The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion
  13. 5573
    “…Samples were analyzed using microbiological (survival rates), morphological (electron microscopy), biochemical (GC-MS, Microarray immunoassay, Rock-Eval) and spectroscopic (EDX, FTIR, RAMAN spectroscopy) methods. …”
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    Mineralization and Preservation of an extremotolerant Bacterium Isolated from an Early Mars Analog Environment
  14. 5574
    “…Significant research effort has focused on improving the specific energy of lithium-ion batteries for emerging applications, such as electric vehicles. Recently, a rock salt–type Li(4)Mn(2)O(5) cathode material with a large discharge capacity (~350 mA·hour g(−1)) was discovered. …”
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    Interplay of cation and anion redox in Li(4)Mn(2)O(5) cathode material and prediction of improved Li(4)(Mn,M)(2)O(5) electrodes for Li-ion batteries
  15. 5575
    “…Cardiac function was assessed using echocardiography, and cardiac eNOS and ROCK expression were measured using immunohistochemistry. …”
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    Progressive Decrease in Coronary Vascular Function Associated With Type 2 Diabetic Heart Disease
  16. 5576
    “…More significantly, the combination of Δ133p53α overexpression and ROCK inhibitor, without feeder cells, enables primary epithelial cells to be propagated long-term in vitro. …”
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    Δ133p53α, a natural p53 isoform, contributes to conditional reprogramming and long-term proliferation of primary epithelial cells
  17. 5577
    “…Therefore, these results suggest that the sequential Wnt5a/RhoA/ROCK/JNK pathway is involved in IL-1β-induced neuronal differentiation of NPCs. …”
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    Interleukin-1 beta promotes neuronal differentiation through the Wnt5a/RhoA/JNK pathway in cortical neural precursor cells
  18. 5578
    “…Next, we investigated the effect of several NK1R internalization factors on RANTES expression, including GRK2, β-arrestin 2, dynamin, ROCK, and TGFβ1. Exposure of macrophages to SP upregulated TGFβ1 expression. …”
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    Cross-talk between the transcription factor Sp1 and C/EBPβ modulates TGFβ1 production to negatively regulate the expression of chemokine RANTES
  19. 5579
    “…We evaluated whether LIM-kinase 2 inhibitor (LIMK2i) could improve erectile function by suppressing corporal fibrosis through the normalization of the Rho-associated coiled-coil protein kinase 1 (ROCK1)/LIMK2/Cofilin pathway in a rat model of cavernous nerve crush injury (CNCI). …”
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    Role of inhibiting LIM-kinase2 in improving erectile function through suppression of corporal fibrosis in a rat model of cavernous nerve injury
  20. 5580
    por Wang, Lei, Chen, Xiaoxia, Xia, Zunyi
    Publicado 2018
    “…In the past few decades, scholars have made great breakthroughs in the study of well test analysis of carbonate rock. The previous studies are based on horizontal wells, straight wells, fractured wells, and inclined wells. …”
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    A Novel Semi-Analytical Model for Multi-branched Fractures in Naturally Fractured-Vuggy Reservoirs
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