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5601por Li, Xiang, Peng, Zhiming, Long, Lingli, Lu, Xiaofang, Zhu, Kai, Tuo, Ying, Chen, Ningning, Zhao, Xiaoyang, Wang, Le, Wan, Yong“…Wnt5a could reduce RhoA expression by upregulating miRNA200b-3p expression to inhibit activation of the RhoA/Rock signaling pathway, which has been reported to suppress neuronal differentiation. …”
Publicado 2020
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5602por Vargas Hoyos, Harold Alexander, Chiaramonte, Josiane Barros, Barbosa-Casteliani, Ana Gabriele, Fernandez Morais, Jorge, Perez-Jaramillo, Juan Esteban, Nobre Santos, Suikinai, Nascimento Queiroz, Sonia Claudia, Soares Melo, Itamar“…Soil in its natural condition (with no phosphorus addition), 40 kg ha(–1) rock phosphate from Bayovar (RP) added to soil, and triple super phosphate (SPT) added to soil were used. …”
Publicado 2021
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5603por Sun, Ju, Sun, Ruifang, Li, Chao, Luo, Xun, Chen, Jiemei, Hong, Jiena, Zeng, Yan, Wang, Qing Mei, Wen, Hongmei“…Furthermore, 50-54% of rats in the tMCAO(90min )group developed significant cognitive impairment on day 28, and thalamic NgR1, RhoA, and ROCK expression were greater in tMCAO(90min) rats than in sham rats. …”
Publicado 2021
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5604“…However, rock salt undergoes non-linear creep deformation due to long-term loading caused by subsurface storage. …”
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5605por Eddy, Christopher Z., Raposo, Helena, Manchanda, Aayushi, Wong, Ryan, Li, Fuxin, Sun, Bo“…We find that morphodynamics of 3D migrating cells are externally controlled by ECM mechanics and internally modulated by Rho/ROCK-signaling. We employ machine learning to classify cell shape into four different morphological phenotypes, each corresponding to a distinct migration mode. …”
Publicado 2021
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5606por Innico, Georgie, Gobbi, Laura, Bertoldi, Giovanni, Rigato, Matteo, Basso, Anna, Bonfante, Luciana, Calò, Lorenzo A.“…In nine patients under PD OxSt in terms of mononuclear cell protein level of p22(phox) (Western blot), subunit of NADPH oxidase, essential for the generation of OxSt, and MYPT‐1 phosphorylation state (Western blot), a marker of ROCK activity, have been measured at the beginning and after 3 and 6 months of PD. …”
Publicado 2021
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5607por Rajagopalan, Uma Maheswari, Wakumoto, Ryotaro, Endo, Daiki, Hirai, Minoru, Kono, Takahiro, Gonome, Hiroki, Kadono, Hirofumi, Yamada, Jun“…The temporal correlation between the frames was characterized by a parameter called biospeckle activity (BA)under the exposure to different sound stimuli of classical and rock music and single-frequency sound stimuli for 1min. …”
Publicado 2021
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5608“…LSWF is a complex process controlled by several mechanisms and parameters involving oil, brine, and rock composition. The major mechanisms and processes controlling LSWF are still being debated in the literature. …”
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5609por Zheng, Huaqing, Li, Xiaolong, Zeng, Xin, Huang, Chengcui, Ma, Mingming, Lv, Xiaofei, Zhang, Yajuan, Sun, Lu, Wang, Guanlei, Du, Yanhua, Guan, Yongyuan“…TMEM16A overexpression inhibited AngII-induced RhoA/ROCK2 activation, and myosin light chain phosphatase (MLCP) and myosin light chain (MLC20) phosphorylation. …”
Publicado 2021
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5610“…The LIM kinases (LIMK1 and LIMK2), known as downstream effectors, and the Rho-associated protein kinase (ROCK), a regulator of actin dynamics, have effects on a diverse set of cellular functions. …”
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5611por Mondaca‐Ruff, David, Quiroga, Clara, Norambuena‐Soto, Ignacio, Riquelme, Jaime A., San Martin, Alejandra, Bustamante, Mario, Lavandero, Sergio, Chiong, Mario“…Moreover, Bag3 is increased in response to Ang II by a AT1R/ROCK signalling pathway. These data provide preliminary evidence suggesting that Ang II may stimulate autophagy in VSMCs by increasing total LC3 content and LC3 processing.…”
Publicado 2022
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5612por De Ieso, Michael L., Kuhn, Megan, Bernatchez, Pascal, Elliott, Michael H., Stamer, W. Daniel“…Using phosphorylated myosin light chain (pMLC) as a surrogate indicator for Rho/ROCK activity and contractile tone, we found that pMLC was elevated in Cav1-deficient TM cells compared to control (131 ± 10%, n = 10, p = 0.016). …”
Publicado 2022
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5613por Krieger, Chantal Selina, Vesa, Doris-Viviana, Ziegenhorn, Stephan, Exadaktylos, Aristomenis Konstantinos, Klukowska-Rötzler, Jolanta, Brodmann Maeder, Monika“…OBJECTIVES: Outdoor rock climbing has become popular in recent years. …”
Publicado 2022
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5614por Xia, Ning, Yang, Nannan, Shan, Qungang, Wang, Ziyin, Liu, Xiaoyu, Chen, Yingjie, Lu, Jian, Huang, Wei, Wang, Zhongmin“…Next, we identified RhoA as a downstream target of HNRNPC and showed that inhibition of the RhoA/ROCK2‐YAP/TAZ pathway led to a reduction in DNA damage repair and radiation resistance. …”
Publicado 2022
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5615“…In the case of wettability improvement, the BPS value of a crude oil-brine-rock (COBR) system should be at its minimum value. …”
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5616por Xie, Weidong, Gan, Huajun, Chen, Chongyu, Vandeginste, Veerle, Chen, Si, Wang, Meng, Wang, Jiyao, Yu, Zhenghong“…Superimposed accumulation mechanism and model of vertical source rock–reservoir system of coal-measure gas is crucial to evaluate the exploration potential, and also the basis of co-exploration and co-production of coal measure gas. …”
Publicado 2022
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5617por Giraldo, María A., Zabala, Richard D., Bahamón, Jorge I., Ulloa, Juan M., Usurriaga, José M., Cárdenas, José C., Mazo, Camilo, Guzmán, Juan D., Lopera, Sergio H., Franco, Camilo A., Cortés, Farid B.“…Also, the contact angle assessed the alteration of the rock wettability. The nanoparticle with better performance was the raw fumed silica of 7 nm at 1000 mg/L. …”
Publicado 2022
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5618por Mukherjee, Sumit, Kuang, Zhuoran, Ghosh, Samrat, Detroja, Rajesh, Carmi, Gon, Tripathy, Sucheta, Barash, Danny, Frenkel-Morgenstern, Milana, Nevo, Eviatar, Li, Kexin“…In this study, we performed a comparative metagenomic analysis of two sharply divergent rocks and soil types at the Evolution Plateau (EP) in eastern Upper Galilee, Israel. …”
Publicado 2022
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5619por Pahlavani, Hamed Alizadeh“…After exercising in the heart, the levels of RhoA, ROCK1, Rac1, and ROCK2 decrease, while the levels of PKCε, PKCδ, and PKCɑ are activated to regulate calcium and prevent mPTP perforation. …”
Publicado 2022
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5620por Keller, Laura, Tardy, Claudine, Ligat, Laetitia, Le Pennec, Soazig, Bery, Nicolas, Koraïchi, Faten, Chinestra, Patrick, David, Mélissa, Gence, Rémi, Favre, Gilles, Cabantous, Stéphanie, Olichon, Aurélien“…This strategy led us to identify a functional intracellular nanobody, hereafter named RH28, that does not cross-react with the close RAC subfamily and blocks/disrupts the RHOA/ROCK signaling pathway in several cell lines without further engineering or functionalization. …”
Publicado 2022
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