“…Moreover, their ability to function as adipose-like microtissue models for drug screening was demonstrated by confirming its sensitivity to TNFα and ROCK inhibitor, respectively involved in the repression and induction of the adipogenic differentiation.…”
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“…Here we present molecular, microscopic, and metagenomic evidence that cyanobacteria predominate in deep subsurface rock samples from the Iberian Pyrite Belt Mars analog (southwestern Spain). …”
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“…This was followed in 1997 by research on Vryburg hepatosis, another area-specific mineral imbalance–related disease in young calves reared on manganese-rich soil derived from the weathering of dolomitic (carbonate) rock formations. In 1982, a totally new syndrome (osteochondrosis) manifested in, amongst others, areas in South Africa where aphosphorosis was rife. …”
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“…Here, we use spatially-explicit point-process modeling to explore the potential relations between ahu construction locations and subsistence resources, namely, rock mulch agricultural gardens, marine resources, and freshwater sources—the three most critical resources on Rapa Nui. …”
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“…This can be achieved by sorting cells onto a feeder layer of MEFs in a stem cell defined medium with KSR and a Rock inhibitor, as early as 1–2 days following a transfection, streamlining the gene editing process. …”
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“…Chemical EOR methods modify different properties of fluids and/or rock to mobilize the remaining oil. Moreover, combined techniques have been developed to maximize the performance by using the joint properties of the chemical slugs. …”
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“…In this study, we analyzed host health and fitness responses to increasing ectoparasite burdens along with the presence/absence of hemoparasites of free‐ranging insular rock iguanas (Cyclura cychlura) in The Bahamas. Using hematology, plasma biochemistry, as well as body condition and growth rate comparisons, we failed to find significant associations of tick burdens with annual growth rate, corticosterone, packed cell volume, total white blood cell, and heterophil, monocyte, eosinophil or hemoglobin measures. …”
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“…Three commonly used aggregate types (granite, basic rock, and limestone) and two asphalt binder types were used in laboratory testing. …”
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“…METHODS AND RESULTS: Here, we highlight the use of iButtons in three distinct settings: comparisons of empirical data to modeled climate data for rare rock ferns in the genus Asplenium in eastern North America; generation of fine‐scale data to predict flowering time and vernalization responsiveness of crop wild relatives of chickpea from southeastern Anatolia; and measurements of extreme thermal variation of solar array installations in Vermont. …”
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“…Here, we use high-throughput sequencing of the 16S and 18S rRNA genes to describe the bacterial and eukaryotic community compositions in cryoconite holes and surrounding lake, snow, soil and rock samples in Queen Maud Land. We cross correlate our findings with a broad range of geochemical data including for the first time (13)C and (14)C analyses of Antarctic cryoconites. …”
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“…In sensory neurons, Rho GTPases are activated by various extracellular signals through membrane receptors and elicit their action through a wide range of downstream effectors, such as Rho-associated protein kinase (ROCK), phosphoinositide 3-kinase (PI3K) or mixed-lineage kinase (MLK). …”
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“…We show that seismic slip and associated melting are preceded by fracturing, asymmetric fragmentation, and comminution of the wall rock caused by a dynamically propagating rupture. …”
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“…RhoA acts as a molecular switch that is activated in response to binding of chemokines, cytokines, and growth factors, and via mDia and the ROCK signaling cascade regulates the activation of cytoskeletal proteins, and other factors. …”
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“…The species number in the studied pools increased, not only with the proportion of stones and rock covering the pool bottom, but also with pool facilities, for example, the supply of boulders and a high coverage of macro-algae. …”
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“…Four bacterial consortia composed of Methylocystis and Methylosinus originating from Sphagnum flexuosum (Sp1), S. magellanicum (Sp2), S. fallax II (Sp3), S. magellanicum IV (Sp4), and one composed of Methylocaldum, Methylosinus, and Methylocystis that originated from coalbed rock (Sk108) were studied. Nutritional elements were determined using the flame atomic absorption spectroscopy technique after a biomass mineralization stage, whereas the fatty acid content was analyzed with the GC technique. …”
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“…Gibb's figure revealed that underground water pre-eminence distribution is probably resulted by water-rock dominance in sub-surface water.…”
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“…If cultures seemed to be reaching their Hayflick limit when cultivated at 3% O(2), supplementing the culture media with 5 µM ROCK inhibitor Y-27632 helped to extend proliferation and achieve spontaneous immortalization. …”
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“…These data indicate that the selenium isotopic composition of peridotites is unaffected by petrological processes, such as melt depletion and melt-rock reaction, and thus a narrow range is preserved that is representative of the silicate Earth. …”
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“…In addition, we found that nuclear flattening mediates TEAD and AP1 activation in response to ROCK‐generated contractility or cell spreading. Our results reveal that the nuclear envelope can operate as a mechanical sensor whose deformation controls cell growth in response to tension.…”
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“…Previous studies suggest that thin meltwater films between the overlying ice and a hard-rock bed channelize into efficient drainage elements by melting the overlying ice. …”
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