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6421“…A major challenge in theoretical ecology is understanding how natural microbial communities support species diversity(1-8), and in particular how antibiotic producing, sensitive and resistant species coexist(9-15). While cyclic “rock-paper-scissors” interactions can stabilize communities in spatial environments(9-11), coexistence in unstructured environments remains an enigma(12,16). …”
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6422“…The peak metamorphism of the garnet websterite was after ∼1.90 Ga when it was subducted to eclogite facies at ∼2.4 GPa, then exhumed back to granulite facies at ∼0.9 GPa before ∼1.82 Ga. The rock associations with their structural relationships and geochemical affinities are comparable to those of supra-subduction zone ophiolites, and supported by subduction-related signatures of gabbros and basalts. …”
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6423“…Specific therapies targeting pulmonary hypertension include calcium channel blockers, endothelin (ET-1) receptor antagonists, prostacyclin analogs, phosphodiesterase type 5 (PDE5) inhibitors, and rho-kinase (ROCK) inhibitors. Newer antifibrotic and anti-inflammatory agents may exert beneficial effects on heart failure in idiopathic pulmonary fibrosis. …”
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6424“…For this purpose, we constructed artificial assemblages with different combinations of morphological groups and increasing levels of fragmentation by manipulating the amount of bare rock or the spatial arrangement of different species in mixed assemblages. …”
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6425por Boyce, Jeremy W., Treiman, Allan H., Guan, Yunbin, Ma, Chi, Eiler, John M., Gross, Juliane, Greenwood, James P., Stolper, Edward M.“…Instead, (37)Cl/(35)Cl correlates positively with Cl abundance in apatite, as well as with whole-rock Th abundances and La/Lu ratios, suggesting that the high (37)Cl/(35)Cl in lunar basalts is inherited from urKREEP, the last dregs of the lunar magma ocean. …”
Publicado 2015
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6426“…This revealed critical features of the column, distal arms, and aboral cup, which were hidden in the surrounding rock and would have been inaccessible without the application of micro-CT. …”
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6427“…While advances have been made in the sedimentary realm, our understanding of the igneous rock portion as a microbial habitat has remained limited. …”
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6428“…The internal structure shows steeply dipping rock units and foliation. Earlier dextral ductile shear fabrics of likely late Early Cretaceous age are preserved in sulphate rocks and are subsequently overprinted by mylonitic fabrics in rocksalt and cataclastic fabrics in other rocks. …”
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6429“…The foliation planes of the mylonitic host rock intersect the faults approximately at their centre and exhibit ductile reverse drag. …”
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6430“…In the Hallstatt salt mine (Austria), polyhalite rocks occur in 0.5–1 m thick and several metre long tectonic lenses within the protocataclasite to protomylonite matrix of the Alpine Haselgebirge Fm.. …”
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6431por de Kreuk, Bart-Jan, Gingras, Alexandre R, Knight, James DR, Liu, Jian J, Gingras, Anne-Claude, Ginsberg, Mark H“…HEG1 binds to a central region of Rasip1 and deletion of this domain eliminates Rasip1’s ability to bind HEG1, to translocate to EC junctions, to inhibit ROCK activity, and to maintain EC junctional integrity. …”
Publicado 2016
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6432por Wang, Yurong, Wang, Bin, Guerram, Mounia, Sun, Li, Shi, Wei, Tian, Chongchong, Zhu, Xiong, Jiang, Zhenzhou, Zhang, Luyong“…Although the RhoA/ RhoA kinase (ROCK) signaling pathway is implicated in DPT-stimulated cytoskeleton remodeling and tumor vasculature suppressing, the detailed mechanisms by which DPT mediates these effects are poorly understood. …”
Publicado 2015
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6433por Shafqat-Abbasi, Hamdah, Kowalewski, Jacob M, Kiss, Alexa, Gong, Xiaowei, Hernandez-Varas, Pablo, Berge, Ulrich, Jafari-Mamaghani, Mehrdad, Lock, John G, Strömblad, Staffan“…Additional analyses illuminate the macromolecular- and cellular-scale effects of molecular targeting (fibronectin, talin, ROCK), including 'adaptive switching' between Continuous (favored at high adhesion/full contraction) and Discontinuous (low adhesion/inhibited contraction) modes. …”
Publicado 2016
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6434“…Various vegetation and soil variables were significantly correlated. The available K and rock content were good explanatory variables, and they were positively correlated with tree volume. …”
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6435por Meyer, Julie L., Jaekel, Ulrike, Tully, Benjamin J., Glazer, Brian T., Wheat, C. Geoffrey, Lin, Huei-Ting, Hsieh, Chih-Chiang, Cowen, James P., Hulme, Samuel M., Girguis, Peter R., Huber, Julie A.“…The rock-hosted, oceanic crustal aquifer is one of the largest ecosystems on Earth, yet little is known about its indigenous microorganisms. …”
Publicado 2016
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6436por Nur, Tanjina, Loganathan, Paripurnanda, Kandasamy, Jaya, Vigneswaran, Saravanamuthu“…However, this phosphate, if economically recovered, can partly overcome the anticipated future scarcity of phosphorus (P) resulting from exhaustion of natural phosphate rock reserves. An experiment was conducted to determine the efficiency of removing phosphate from a membrane bioreactor effluent (pH 7.0–7.5, 20, 35 mg phosphate/L) produced in a water reclamation plant by adsorption onto Dowex 21K XLT ion exchange resin and recover the phosphate as fertilisers. …”
Publicado 2016
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6437por Horneck, Gerda, Walter, Nicolas, Westall, Frances, Grenfell, John Lee, Martin, William F., Gomez, Felipe, Leuko, Stefan, Lee, Natuschka, Onofri, Silvano, Tsiganis, Kleomenis, Saladino, Raffaele, Pilat-Lohinger, Elke, Palomba, Ernesto, Harrison, Jesse, Rull, Fernando, Muller, Christian, Strazzulla, Giovanni, Brucato, John R., Rettberg, Petra, Capria, Maria Teresa“…In the context of this roadmap, astrobiology is understood as the study of the origin, evolution, and distribution of life in the context of cosmic evolution; this includes habitability in the Solar System and beyond: • Research Topic 1: Origin and Evolution of Planetary Systems; • Research Topic 2: Origins of Organic Compounds in Space; • Research Topic 3: Rock-Water-Carbon Interactions, Organic Synthesis on Earth, and Steps to Life; • Research Topic 4: Life and Habitability; • Research Topic 5: Biosignatures as Facilitating Life Detection. …”
Publicado 2016
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6438por Ota, Shuhei, Yoshihara, Mai, Yamazaki, Tomokazu, Takeshita, Tsuyoshi, Hirata, Aiko, Konomi, Mami, Oshima, Kenshiro, Hattori, Masahira, Bišová, Kateřina, Zachleder, Vilém, Kawano, Shigeyuki“…Phosphorus is an essential element for life on earth and is also important for modern agriculture, which is dependent on inorganic fertilizers from phosphate rock. Polyphosphate is a biological polymer of phosphate residues, which is accumulated in organisms during the biological wastewater treatment process to enhance biological phosphorus removal. …”
Publicado 2016
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6439“…We also review promising neuroregenerative therapies that are likely to influence management practices over the next decade including chondroitinase, Rho-ROCK pathway inhibition, and bioengineered strategies. …”
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6440por Panousopoulou, Eleni, Hobbs, Carl, Mason, Ivor, Green, Jeremy B. A., Formstone, Caroline J.“…The radial cell rearrangements that drive epidermal spreading also require ROCK activity but are driven by cell protrusions and not myosin II contractility. …”
Publicado 2016
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