“…Moreover, expressions of RhoA, Rho-associated protein kinase 1/2 (ROCK1/2), and phosphorylated myosin light chain (p-MLC) were also downregulated by QSKL compared with the model group. …”
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“…PURPOSE OF REVIEW: More than a century of hard rock mining has left a legacy of >160,000 abandoned mines in the Western USA that are home to the majority of Native American lands. …”
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“…Important in their early evolution was impact-driven lithification, where a porous mixture of millimetre-scale chondrule inclusions and sub-micrometre dust was compacted into rock. In this Article, the shock compression of analogue precursor chondrite material was probed using state of the art dynamic X-ray radiography. …”
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“…Integrated analysis of MiRTarBase and RNA-seq identified 12 target genes of microRNAs defining side population, including DDIT4 and ROCK2. The present study indicates that a distinct set of microRNAs may be critically involved in the generation and maintenance of heterogeneous subpopulations of cancer cells. …”
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“…We also observed arboreal geckos with relatively shorter proximal limb segments as compared to rock-dwelling and terrestrial geckos, similar to patterns observed for other lizards. …”
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“…When HUVECs are exposed to the bacterial toxin called epidermal cell differentiation inhibitor (EDIN), which can induce spontaneous transcellular tunnels, less mechanical work is required to form tunnels due to the reduced cytoskeletal stiffness and thickness of these cells, similarly to the effects of a Rho-associated protein kinase (ROCK) inhibitor. We also observe actin enrichment in response to mechanical indentation that is reduced in cells exposed to the bacterial toxin. …”
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“…Analyses of microstructures in the sedimentary rocks and in the basalt of the igneous basement reveal brittle deformation, as well as crystal‐plastic deformation of the host rock and the vein material. …”
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“…Seven environmental factors, namely soil depth, humus depth, soil pH, aspect, slope position, bare rock ratio, and distance to the sea, were significantly correlated with species distribution. …”
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“…They show that the same instability that causes kilometer-thick rock layers to fold on geological timescales is acting here at micrometer level.…”
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“…Formation of highly plant-available compounds such as ammonium phosphates could make secondary P-fertilizers more competitive to commercial phosphate rock-based fertilizers with positive effects on resources conservation. …”
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“…It has been recently demonstrated that these shapes could have been the result of the negative feedback between stress and erosion that originates in fundamental laws of friction between the rock’s constituent particles. Here we present a deeper analysis of this idea and bridge it with the approaches utilized in shape and topology optimisation. …”
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“…We also review the current pharmacological tools such as NSAIDs, RhoA/ROCK, Rac1, and Cdc42 inhibitors used to target Rho GTPases and their use in AD-related studies. …”
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“…Solid organic matter (OM) plays an essential role in the generation, migration, storage, and production of hydrocarbons from economically important shale rock formations. Electron microscopy images have documented spatial heterogeneity in the porosity of OM at nanoscale, and bulk spectroscopy measurements have documented large variation in the chemical composition of OM during petroleum generation. …”
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“…Microbial life can leave various traces (or biosignatures) in rocks, including biotic alteration textures, biominerals, enrichments of certain elements, organic molecules, or remnants of DNA. …”
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“…We also suggest that the earliest rock art found in Africa may constitute one of the first fossilized proxies for the expression of full-fledged human linguistic behavior.…”
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“…; (3) How much variability in rock and soil substrate endmembers (EMs) present in hyperspectral data is captured by multispectral sensors? …”
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“…RESULT AND DISCUSSION: It was observed that noise induced by HEMM such as rock breakers, jackhammers, dumpers, and excavators, blasting noise in the mining terrain, as well as associated transportation noise became a major source of annoyance to the habitants living in proximity to the mines. …”
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“…In order to address geological processes at great depths, rock deformation should ideally be tested at high pressure (> 0.5 GPa) and high temperature (> 300 °C). …”
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“…It is assumed that microorganisms play an important role in the transformations of these sedimentary rocks and contribute to the return of organic carbon and inorganic sulfur to the global geochemical cycles. …”
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“…Methods have been described to generate rapidly proliferating epithelial cell cultures from multiple human epithelia using 3T3‐J2 feeder cell culture in the presence of Y‐27632, a RHO‐associated protein kinase (ROCK) inhibitor, in what are known as “conditional reprograming conditions” (CRC) or 3T3 + Y. …”
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