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  1. 7001
    “…The genotype-selective rescue was dependent upon increased RhoA protein levels in mutant huntingtin-expressing cells, because inhibition of RhoA, its downstream effector, Rho-associated kinase (ROCK), or a microtubule-associated RhoA activator, guanine nucleotide exchange factor-H1 (GEF-H1), all attenuated the rescue. …”
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    Mutant Huntingtin Alters Cell Fate in Response to Microtubule Depolymerization via the GEF-H1-RhoA-ERK Pathway
  2. 7002
    por Lüttge, Ulrich
    Publicado 2010
    “…TROPICAL CAM HABITATS: Typical tropical CAM habitats or ecosystems include exposed lava fields, rock outcrops of inselbergs, salinas, savannas, restingas, high-altitude páramos, dry forests and moist forests. …”
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    Ability of crassulacean acid metabolism plants to overcome interacting stresses in tropical environments
  3. 7003
    “…As between population differentiation was lower in the wild than differentiation between pond-raised versus wild fish, we suggest the narrow ecological niche and intense interspecific competition in rock habitats is responsible for consistent shape similarity, even among long-term isolated populations. …”
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    Morphological distinctness despite large-scale phenotypic plasticity—analysis of wild and pond-bred juveniles of allopatric populations of Tropheus moorii
  4. 7004
    “…Sarcocheilichthys biwaensis, a rock-dwelling specialist, exhibited similar morphologies to the sympatric congener, S. v. microoculus, except for body/fin coloration. …”
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    A Novel Resource Polymorphism in Fish, Driven by Differential Bottom Environments: An Example from an Ancient Lake in Japan
  5. 7005
    “…A 15-year old East African immune-competent boy with a history of smear-positive tuberculosis and a two-year history of rock cutting presented to our hospital with chronic productive cough, fever, and massive unilateral consolidation. …”
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    Pulmonary histoplasmosis presenting as chronic productive cough, fever, and massive unilateral consolidation in a 15-year-old immune-competent boy: a case report
  6. 7006
    “…For example, spatial variation in patterns of selection or limited gene flow can cause entire populations to become fixed for a single morph, resulting in separate populations of the same species exhibiting separate and distinct color morphs. The mottled rock rattlesnake (Crotalus lepidus lepidus) is a montane species that exhibits among-population color polymorphism that correlates with substrate color. …”
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    Predation and the Maintenance of Color Polymorphism in a Habitat Specialist Squamate
  7. 7007
    “…Furthermore, a fraction (F4.6.3) inducing or keeping up expression of the mobility markers MYPT, ROCK1, and paxillin could be separated from another fraction (F4.3.7), which inhibited these markers. …”
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    Fractionation of an Extract of Pluchea odorata Separates a Property Indicative for the Induction of Cell Plasticity from One That Inhibits a Neoplastic Phenotype
  8. 7008
    “…The effects of rosuvastatin on actin-cytoskeleton dynamics and cell migration were dependent on ROCK-signalling. Furthermore, rosuvastatin caused a significant increase in RhoA-GTP in the cytosol of VSMC. …”
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    LDL-Induced Impairment of Human Vascular Smooth Muscle Cells Repair Function Is Reversed by HMG-CoA Reductase Inhibition
  9. 7009
    “…The kinase domain is again fused to an extended C-terminal coiled-coil domain reminiscent of eukaryotic DMPK (Myotonic Dystrophy Protein Kinase) family kinases such as Rho-associated protein kinase (ROCK). WbdD phosphorylates 2-α-d-mannosyl-d-mannose (2α-MB), a short mimic of the O9a polymer. …”
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    Structure of WbdD: a bifunctional kinase and methyltransferase that regulates the chain length of the O antigen in Escherichia coli O9a
  10. 7010
    por Jones, Sarah E., Palmer, Timothy M.
    Publicado 2012
    “…These results suggest that PKA-mediated inhibition of RhoA via its phosphorylation on serine 188 and the subsequent inhibition of ROCK activity plays a key role in determining initial changes in cellular morphology during LNCaP cell differentiation to a neuroendocrine phenotype. …”
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    Protein kinase A-mediated phosphorylation of RhoA on serine 188 triggers the rapid induction of a neuroendocrine-like phenotype in prostate cancer epithelial cells
  11. 7011
    por Park, Il-Ho, Lee, Heung-man
    Publicado 2012
    “…CONCLUSIONS: We showed that simvastatin inhibits TGF-β1-induced myofibroblast differentiation (expression of α-SMA) and collagen production in NPDFs and Rho/Rock and TGF-β/Smad signaling is involved as an underlying mechanism. …”
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    153 Effect of Simvastatin on Transforming Growth Factor BETA-1-Induced Myofibroblast Differentiation and Collagen Production in Nasal Polyp-Derived Fibroblasts
  12. 7012
    “…The goal of this study was to characterize the Cro1 strain 780032I that was isolated in cell culture from a rock rattlesnake (Crotalus lepidus) in the original outbreak. …”
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    Genetic characterization of a reptilian calicivirus (Cro1)
  13. 7013
    “…Transdifferentiation or reprogramming toward insulin-secreting β-cells was enhanced, however, when using unpassaged cells in combination with inhibition of EMT by inclusion of Rho-associated kinase (ROCK) and transforming growth factor-β1 inhibitors. …”
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    Suppression of Epithelial-to-Mesenchymal Transitioning Enhances Ex Vivo Reprogramming of Human Exocrine Pancreatic Tissue Toward Functional Insulin-Producing β-Like Cells
  14. 7014
    “…Salmonella enterica serovar Typhimurium definitive type 2 (DT2) is host restricted to Columba livia (rock or feral pigeon) but is also closely related to S. …”
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    Genome and Transcriptome Adaptation Accompanying Emergence of the Definitive Type 2 Host-Restricted Salmonella enterica Serovar Typhimurium Pathovar
  15. 7015
    “…Grand skinks occur on scattered rock-outcrops surrounded by indigenous tussock (bunch) and pasture grasslands therefore implying a metapopulation structure. …”
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    Matrix Matters: Differences of Grand Skink Metapopulation Parameters in Native Tussock Grasslands and Exotic Pasture Grasslands
  16. 7016
    “…Rho-assiciated kinase (ROCK) inhibitor Y-27632, a small molecule which enhanced keratinocyte proliferation, significantly interfered with the lentiviral transduction into cultured human keratinocytes. …”
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    Efficient expansion of human keratinocyte stem/progenitor cells carrying a transgene with lentiviral vector
  17. 7017
    “…Based on nine years of observation (2001–2009) inside and outside a well managed MPA, we assessed the potential of conservation and management actions to modify patterns of spatial and/or temporal variability of Posidonia oceanica meadows, the lower midlittoral and the shallow infralittoral rock assemblages. Significant differences in both temporal variations and spatial patterns were observed between protected and unprotected locations. …”
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    Protection Enhances Community and Habitat Stability: Evidence from a Mediterranean Marine Protected Area
  18. 7018
    “…Three pilots including the under-investigation region’s soil planted by Vetiver plant, the region’s intact soil pilot and the artificial composition of the region’s soil including the natural region’s soil, sand, and rock stone are used. The leachate, having passed its initial treatment, passed through the soil and to the pilot. …”
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    Attenuation of municipal landfill leachate through land treatment
  19. 7019
    “…After LPS stimulation, although total RhoA and p120-bound RhoA were unchanged, RhoA activity was increased. Y27632, a ROCK inhibitor, could partially inhibit nuclear translocation of p65. …”
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    p120 Modulates LPS-Induced NF-κB Activation Partially through RhoA in Bronchial Epithelial Cells
  20. 7020
    “…Recent studies in microVSM unraveled a crucial role of Rap1A-Rho-ROCK-F-actin pathways in receptor translocation, and identified protein-protein interaction of α(2C)-ARs with the actin binding protein filamin-2 as an essential step in the process. …”
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    In Silico Modeling of Human α(2C)-Adrenoreceptor Interaction with Filamin-2
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