“…S1P bound to albumin increased PAI-1 expression through the S1P receptor 2-Rho/ROCK-NFκB pathway. Conclusion: S1P bound to albumin, but not to apoM, induces PAI-1 expression in adipocytes, indicating that S1P can exert different properties on the pathogenesis of vascular diseases, depending on its vehicle.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We then investigate the typicality of our results in China’s Changqing oilfield, which is one major centre of tight gas production and where the rock samples for experiments are obtained. It is estimated that a non-negligible portion of 18% tight sandstone samples in this area will probably display viscoelasticity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Mabuyid skinks of the genus Trachylepis are the dominant, fully limbed skinks in Sub-Saharan Africa, and nearly all species have the same generalized body plan. Although a few rock crevice-dwelling species possess slight body depression, extreme dorsoventral depression is observed only in Trachylepis laevis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We hypothesized that enhanced mechanical activity of CAFs, as regulated by the Rho/ROCK pathway, contributes to increased blood vessel growth. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Western blotting and qRT-PCR analysis in NMDA-treated mRGCs and murine retinal tissues revealed that NgR silencing resulted in downregulation of RhoA signaling (RhoA and ROCK2). Western blotting showed that levels of activated Bax and cleaved caspase 3 were decreased, while Bcl-2 and pro-caspase 3 were increased in NMDA-treated mRGCs and murine retinal tissues, which corroborated the decreased apoptosis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: Seventeen context-relevant factors were identified and 10 themes emerged, these being ‘the cold weather ritual’, ‘digestive system conditioning’, ‘the curse of the night owl’, ‘the strings attached to sponsorship’, ‘my coach—my rock’, ‘mood maintenance’, ‘the asynchronous training rhythm’, ‘psychological slavery’, ‘the legacy of the asphalt tattoo’ and ‘the tension of family and friends’. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the spring of 2015, 44 women employed full-time at Slippery Rock University participated in this study. Participants were predominantly Caucasian (95%), middle-aged (48 ± 10 years), and had an average BMI of 30.5 ± 8.2. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Seismic signals generated by different cultural activities, including rock concerts, fireworks or football games, can be detected and discriminated from its seismic properties. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It has been proposed that the subaerial phases of Cretaceous oceanic plateau formation spurred the global environmental deterioration, yet this view is supported by patchy fossil and/or rock evidence for uplifting of the plateau summits above the sea level. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These cacti are allopatric and grow in xeric habitats along BAF, including isolated granite and gneiss rock outcrops (Inselbergs), sand dune vegetation (Restinga forest), and the rocky shore of an oceanic archipelago (islands of Fernando de Noronha). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here we explored the genetic mechanism underlying the expression of discrete mating strategies in the rock-paper-scissors (RPS) game. Heterozygotes carry the genetic information for two different strategies, yet little attention has been devoted to the mechanisms underpinning heterozygote phenotype and its consequences for allele frequency dynamics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To better constrain the Lhasa-Qiangtang collision, a combined palaeomagnetic and geochronological study of the far western Lhasa terrane was conducted on the Duoai Formation lava flows (~113–116 Ma), as well as on the Early Cretaceous Jiega Formation limestone. Following detailed rock magnetic, petrographical, and palaeomagnetic experiments, characteristic remanent magnetisation directions were successfully isolated from most samples using principal component analysis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This process, in turn, recruited PDZ-RhoGEF to the junctions, leading to the RhoA/ROCK/LIM kinase/cofilin-dependent stabilization of the junctions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Furthermore, inhibition of Rho-associated kinase (ROCK) recovered collective cell migration in Tpm2.1-silenced cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It occurs as nanoscale lamellae and has a topotaxial relationship with the host ringwoodite (γ-phase of Mg(2)SiO(4)). Olivine in the host rock entrapped in a shock-induced melt vein initially transformed into polycrystalline ringwoodite through a nucleation and growth mechanism. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Current limitations to primary cell expansion led us to test whether airway epithelial cells derived from healthy children and those with asthma and cystic fibrosis (CF), co-cultured with an irradiated fibroblast feeder cell in F-medium containing 10 µM ROCK inhibitor could maintain their lineage during expansion and whether this is influenced by underlying disease status. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Hydrogen produced during water-rock serpentinization reactions can drive the synthesis of organic compounds both biotically and abiotically. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Plate tectonics and associated subduction are unique to the Earth. Studies of Archean rocks show significant changes in composition and structural style around 3.0 to 2.5 Ga that are related to changing tectonic regime, possibly associated with the onset of subduction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We here report on an experiment where two types of biochar, produced from olive husks at 450 °C or from forest waste at 850 ° C were mixed with volcanic rock or peat, and tested for retention capacity of phenanthrene and six heavy metals in a column experiment with unsaturated gravimetric water flow lasting for 3 weeks. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Multi functional research surveys of the T/S Fukae Maru in this caldera, including multi-beam echosounder mapping, remotely operated vehicle observation, multi-channel seismic reflection survey, and rock sampling by dredging and diving, provided lines of evidence for creation of a giant rhyolite lava dome (~32 km(3)) after the caldera collapse. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso