“…This is particularly true for mantidflies (Neuroptera: Mantispidae), which have a scarce fossil record mostly based on rock compressions, namely isolated wings. Here, Aragomantispa lacerata gen. et sp. nov. is described from ca. 105-million-year-old San Just amber (Spain), representing the oldest and one of the few mantidflies hitherto described from amber. …”
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“…The results showed the following: (1) the suitable cover type was cobble and rock substrate, with nearby sandy land; furthermore, the suitable water depth was 0.5–1.5 m, and the suitable velocity was 0.1–0.9 m/s. (2) Using the proximity index to analyse the connectivity of suitable habitats, the range of ecological discharge determined by the WUA and connectivity was 424–1060 m/s. (3) Habitat quality was divided into three levels to detail the flow demand further. …”
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“…Meanwhile, correcting dendritic architecture by inhibiting the cytoskeletal regulatory protein ROCK remedied instrumental response updating defects in socially isolated mice. …”
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“…There is also a prevalence of chemotaxis and motility genes, indicating adaptive strategies for this nutrient-limited fluid-rock environment. These findings provide the first genomic interpretations of the Hydrothermarchaeota phylum and highlight the anoxic, hot, deep marine crustal biosphere as an important habitat for understanding the evolution of early life.…”
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“…Hepatocellular carcinoma (HCC) is one of the most malignant cancers and the treatment options for this disease are limited and generally not effective. ROCK has been reported to be highly expressed in many cancer types and its inhibitor Fasudil has shown anti-cancer potential. …”
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“…During the Holocene and the previous interglacial period (Eemian) the dust record was dominated by coarse particles consistent with rock samples from central East Greenland. From the coarse particle concentration record we infer the East Greenland ice sheet margin advanced from 113.4 ± 0.4 to 111.0 ± 0.4 ka BP during the glacial onset and retreated from 12.1 ± 0.1 to 9.0 ± 0.1 ka BP during the last deglaciation. …”
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“…It has a sawtooth-like profile where each facet reproduces the (100) surface of rock-salt NaCl, hinting on the preferred growth of the (100) surface. …”
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“…Embedded smart temperature sensors (SmartRock) and PZT (piezoelectric) sensors were used for the data acquisition of hydration temperature history and wave propagation. …”
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“…There was also no indication for MCP-induced solubilization of Ca-phosphates on a calcareous sub-soil fertilized with rock-phosphate. The results demonstrate that the combination of multiple PGPM strains with complementary properties as MCP inoculants does not necessarily translate into plant benefits in challenging environments. …”
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“…Silencing the α7-nAChR reduced the viability of HCC cells, suppressed cellular proliferation, attenuated migration and invasion, and diminished the tumor’s sphere-formation ability, with concurrent downregulation of expression levels of the TGR5, p-JAK2, p-STAT3 (Tyr705/Ser727), RhoA, ROCK1, MMP2, and MMP9 proteins. Furthermore, a positive correlation was found between α7-nAChR and JAK2 expressions (p = 0.01) in HCC specimens, as well as their membranous co-localization. …”
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“…In our attempt not only to complement but also to extend the capability beyond available models, the derived model accounts for multiple fundamental variables, such as the microstructural parameters and rock lithology of porous media. Results suggest that, there is a negative correlation between PVC and initial porosity, if all other parameters are fixed, the relationship between initial porosity and PVC is not monotonic. …”
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“…Garnet is the archetypal cubic mineral, occurring in a wide variety of rock types in Earth’s crust and upper mantle. Owing to its prevalence, durability and compositional diversity, garnet is used to investigate a broad range of geological processes. …”
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“…Magnetic resonance imaging (MRI) of the brain showed “in correspondence of the petrous rock and the mastoid…presence of flogistic tissue.” …”
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“…The dominant soil units identified are Leptosol and bare rock (19% coverage), Vertic Cambisol (14%), Regosol and Cambisol (10%), Skeletic/Leptic Cambisol and Regosol (9%), Rendzic Leptosol (7%), Calcaric/Calcic Vertisol (6%), Chromic Luvisol (6%) and Chromic/Pellic Vertisol (5%). …”
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“…Notable exceptions are massifs of fissured rock with caves and hollow spaces reaching depths of two kilometres and more. …”
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“…Furthermore, we found in MDA-MB-231 breast cancer cells that the inhibition of migration is mediated by the GPCR gastrin releasing peptide receptor (GRPR) leading to a reduced expression of migration regulating downstream targets like CDC42 and ROCK1. An in silico Kaplan Meier analysis revealed that GRK5 and GRPR overexpression reduces the distant metastasis free survival in triple-negative breast cancer (TNBC) patients. …”
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“…During the early-Late Holocene, humans took increasing advantage of robust clam populations and after 3.5 ka, began constructing clam gardens (intertidal rock-walled terraces). Environmental and cultural variables, including coarse substrate, stabilized sea surface temperature, and the presence of a clam garden wall, increased clam growth throughout the Holocene. …”
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“…In this study, we explored the effects of fasudil, a selective RhoA–Rho-associated kinase (ROCK) inhibitor, on Th17 cells and the pathogenesis of schistosomiasis. …”
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“…The greater the PC (or PC + FA) content, and more importantly the longer the curing period, the closer the axial stress level required to initiate localization to the UCS, thus emulating the failure mechanism of quasi-brittle materials such as rock and concrete. Finally, with an increase in curing time, the difference between strain values at the localized and non-localized zones became less significant in the pre-peak regime and more pronounced in the post-peak regime.…”
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“…In order to understand the influence of unloading on the mechanical properties of shale rock, triaxial unloading tests under different stress paths were conducted. …”
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