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  1. 8181
    por Wang, Yicun, Wang, Keyong, Konare, Yassa
    Publicado 2018
    “…Oxygen and hydrogen isotopic data (δD = −74.9‰~−77‰, δ(18)O = 9.6‰~12‰, V-SMOW) suggest that the mineralizing fluids were composed of mixed magmatic and metamorphic water, N(2)-rich inclusions (δ(15)N = −0.5‰ to 1.4‰) indicate fluid-rock interaction with metamorphic rocks. The N(2)-rich fluid was closely associated with scheelite precipitation. …”
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    N(2)-rich fluid in the vein-type Yangjingou scheelite deposit, Yanbian, NE China
  2. 8182
    “…Iron is a common pollutant in waters near coal and hard rock mine disturbances. The current 1000 µg/L total recoverable chronic criterion for iron (Fe) for protection of aquatic life in the United States was developed using very limited data in 1976 and has not been revised since. …”
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    Chronic Toxicity of Ferric Iron for North American Aquatic Organisms: Derivation of a Chronic Water Quality Criterion Using Single Species and Mesocosm Data
  3. 8183
    “…He had noticed a small skin abrasion on the right ankle after slipping on a rock during a jungle trip on Seram Island. Back in the Netherlands, a painful ulcer developed at the same body location, and despite treatment with flucloxacillin, his complaints worsened. …”
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    Haemophilus ducreyi cutaneous ulcer contracted at Seram Island, Indonesia, presented in the Netherlands
  4. 8184
    “…Kindia is a subshrub that appears restricted to bare, vertical rock faces of sandstone. Fruit dispersal and pollination by bats is postulated. …”
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    Kindia (Pavetteae, Rubiaceae), a new cliff-dwelling genus with chemically profiled colleter exudate from Mt Gangan, Republic of Guinea
  5. 8185
    “…Furthermore, disaggregation of multicellular EOC spheroids, a behavior associated with dissemination and metastasis, is enhanced by matrix stiffness through a mechanotransduction pathway involving ROCK, actomyosin contractility, and FAK. Finally, this pattern of mechanosensitivity is maintained in highly metastatic SKOV3ip.1 cells. …”
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    The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation
  6. 8186
    “…MTEC were isolated and expanded using the ROCK inhibitor Y-27632 in presence or absence of the γ-secretase inhibitor DAPT, a Notch pathway inhibitor. …”
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    A novel method for expansion and differentiation of mouse tracheal epithelial cells in culture
  7. 8187
    “…Furthermore, miR-222-5p inhibited SMC differentiation by targeting and down-regulating ROCK2 and αSMA. In conclusion, MSC differentiation into SMCs is regulated by miR-503 and miR-222-5p and yields functional SMCs for use in vascular grafts.…”
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    Smooth muscle cells differentiated from mesenchymal stem cells are regulated by microRNAs and suitable for vascular tissue grafts
  8. 8188
    “…Mechanistically, α-synuclein bound to CD11b and subsequently activated Rho signaling pathway. α-Synuclein induced activation of RhoA and downstream ROCK but not Rac1 in a CD11b-dependent manner. Moreover, siRNA-mediated knockdown of RhoA impeded NOX2 activation in response to α-synuclein. …”
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    Integrin CD11b mediates α-synuclein-induced activation of NADPH oxidase through a Rho-dependent pathway
  9. 8189
    “…Physical (substrate type, pool height, subtidal distance and rock coverage), biological (sessile animal coverage) and chemical (salinity) parameters act as the driving forces influencing fish spatial occupancy. …”
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    Endemic fish species structuring oceanic intertidal reef assemblages
  10. 8190
    “…Pharmacological inhibition experiments subsequently revealed that, similar to E‐cadherin‐mutant ILC, anoikis resistance induced by α‐catenin loss was dependent on Rho/Rock‐dependent actomyosin contractility. Finally, using a transplantation‐based conditional mouse model, we demonstrate that inducible inactivation of α‐catenin instigates acquisition of lobular features and invasive behavior. …”
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    αE‐catenin is a candidate tumor suppressor for the development of E‐cadherin‐expressing lobular‐type breast cancer
  11. 8191
    “…Some features include elevation, soil depth, rock volume, precipitation, and vegetation coverage, suggesting that physical, climatic, and biotic landscape features have played a strong evolutionary role restricting gene flow between populations. …”
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    Landscape limits gene flow and drives population structure in Agassiz’s desert tortoise (Gopherus agassizii)
  12. 8192
    “…Improving phosphorus (P) use efficiency to sustain optimum productivity in diverse ecosystems, based on knowledge of soil P dynamics, is also globally important in light of potential shortages of rock phosphate to manufacture P fertilizer. We investigated P chemical speciation and P cycling with solution (31)P nuclear magnetic resonance, P K-edge X-ray absorption near-edge structure spectroscopy, phosphatase activity assays, and shotgun metagenomics in soil samples from long-term agricultural fields containing four different land-use types (native and tame grasslands, annual croplands, and roadside ditches). …”
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    Long-Term Land Use Affects Phosphorus Speciation and the Composition of Phosphorus Cycling Genes in Agricultural Soils
  13. 8193
    “…Phosphogypsum stacks originating from the processing of phosphate rock contain small amounts of radionuclides, such as (226)Ra. …”
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    Fate and transport of radioactive gypsum stack water entering the Floridan aquifer due to a sinkhole collapse
  14. 8194
    “…Liquid oceans and ice caps, along with ice crusts, have long been considered defining features of the Earth, but space missions and observations have shown that they are in fact common features among many of the solar system’s outer planets and their satellites. Interactions with rock-forming materials have produced saline oceans not dissimilar in many respects to those on Earth, where mineral precipitation within frozen seawater plays a significant role in both determining global properties and regulating the environment in which a complex ecosystem of extremophiles exists. …”
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    A slow-cooling-rate in situ cell for long-duration studies of mineral precipitation in cold aqueous environments on Earth and other planetary bodies
  15. 8195
    “…The functional alterations were associated with increased iNOS and ROCK-2 activation in the distal lung.…”
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    Low dose of chlorine exposure exacerbates nasal and pulmonary allergic inflammation in mice
  16. 8196
    “…Slope failure at the terminus of Tyndall Glacier on 17 October 2015 sent 180 million tons of rock into Taan Fiord, Alaska. The resulting tsunami reached elevations as high as 193 m, one of the highest tsunami runups ever documented worldwide. …”
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    The 2015 landslide and tsunami in Taan Fiord, Alaska
  17. 8197
    “…Calcite, ubiquitous in most geological environments, may contain supercritical CO(2) trapped under the form of fluid inclusions that may move through grain boundaries affecting the rock physical properties. However, despite macroscopic evidence for this process, until recent it was not possible to characterize this process at the nano-scale due to the difficulty of such observations. …”
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    Rapid migration of CO(2)-rich micro-fluids in calcite matrices
  18. 8198
    “…Nonsynonymous mutations of 13 genes (MUC5B, TNN, SSPO, PPFIA1, PCDHGA2, ITGA8, ITGA4, DCHS1, CRNN, ROCK1, RELN, LAMC2, and AEBP1) were involved in cell adhesion, and these were only present in the aggressive group. …”
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    Cell adhesion-related gene somatic mutations are enriched in aggressive papillary thyroid microcarcinomas
  19. 8199
    “…Results from western blotting indicated that berberine inhibited the expression of MMP-1, MMP-13, E-cadherin, N-cadherin, RhoA, ROCK1, SOS-1, GRB2, Ras, p-ERK1/2, p-c-Jun, p-FAK, p-AKT, NF-κB, and uPA after 24 h of treatment, but increased the PKC and PI3K in A375.S2 cells. …”
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    Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro
  20. 8200
    “…The identified samples included commercially important pelagic (anchovy, bonito, dolphinfish) and demersal (hake, smooth-hound, Peruvian rock seabass, croaker) fish species. Our results unveiled the marketing of protected and threatened species such as whale shark, Atlantic white marlin, smooth hammerhead (some specimens collected during closed season), shortfin mako, and pelagic thresher sharks. …”
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    A glimpse into the genetic diversity of the Peruvian seafood sector: Unveiling species substitution, mislabeling and trade of threatened species
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