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  1. 8561
    “…The expression levels of these candidate genes as well as ACTB and GAPDH were further analyzed by reverse transcription quantitative real-time PCR in PC12 cells differentiated with a variety of stimuli including NGF, GDNF, Forskolin, KCl and ROCK inhibitor, Y27632. The performances of these candidate genes as stable reference genes were evaluated with two independent statistical approaches, geNorm and NormFinder. …”
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    Normalization with genes encoding ribosomal proteins but not GAPDH provides an accurate quantification of gene expressions in neuronal differentiation of PC12 cells
  2. 8562
    “…CONCLUSIONS: The results indicated that statins suppressed the Rho/Rho-associated coiled-coil-containing protein kinase (ROCK) pathways, thereby inhibiting B16BL6 cell migration, invasion, adhesion, and metastasis. …”
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    Reduction of lung metastasis, cell invasion, and adhesion in mouse melanoma by statin-induced blockade of the Rho/Rho-associated coiled-coil-containing protein kinase pathway
  3. 8563
    “…RESULTS: Anopheles arabiensis utilized a spectrum of man-made and natural aquatic habitats, most of which were concentrated primarily in the rock pools located in ravines and river fringes, and also in the large littoral marshes and within the irrigated agricultural zones. …”
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    Spatial and temporal distribution patterns of Anopheles arabiensis breeding sites in La Reunion Island - multi-year trend analysis of historical records from 1996-2009
  4. 8564
    “…Furthermore, we discovered that this regulation is dependent on RhoA/Rock1 activation. Enhanced phospho-Akt suppression when GSI is combined with rapamycin suggests that targeting both pathways will lead to a greater efficacy in the treatment of patients with pancreas cancer.…”
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    Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation
  5. 8565
    “…Geophysical (gamma ray activity, rock magnetism), geochemical (organic carbon, sulphur) and sedimentological observations were combined with palaeontological information (mainly ostracods). …”
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    Biotic and abiotic response to palaeoenvironmental changes at Lake Pannons' western margin (Central Europe, Late Miocene)
  6. 8566
    por LaBonte, James R.
    Publicado 2011
    “…It has been found in highly degraded heavy industrial sites, agricultural fields, city parks, gardens, second growth woodlands, mature conifer forests, montane rock gardens, and otherwise pristine stands of old growth noble fir, with elevations ranging from essentially sea level to 1,249 meters. …”
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    Nebria brevicollis (Fabricius, 1792) in North America, benign or malign? (Coleoptera, Carabidae, Nebriini)
  7. 8567
    “…The G-proteins Gα(12/13) and Gα(i) were identified as key mediators of LPA signalling via stimulation of RhoA and Rho kinases ROCK1 and 2, activating Rac1, while inhibition of adenylate cyclase and accumulation of cAMP may be secondary. …”
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    Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models
  8. 8568
    por Kurita, Jun, Nakajima, Kazuhiro
    Publicado 2012
    “…Following the identification of RSIV, markedly similar viruses such as infectious spleen and kidney necrosis virus (ISKNV), dwarf gourami iridovirus (DGIV), turbot reddish body iridovirus (TRBIV), Taiwan grouper iridovirus (TGIV), and rock bream iridovirus (RBIV) were isolated in East and Southeast Asia. …”
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    Megalocytiviruses
  9. 8569
    “…Bears were darted in anthill, soil, or uprooted tree dens on eleven occasions, but two bears in rock dens fled and were darted outside the den. We used medetomidine at 0.02–0.06 mg/kg and zolazepam-tiletamine at 0.9–2.8 mg/kg for anesthesia. …”
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    Capture, Anesthesia, and Disturbance of Free-Ranging Brown Bears (Ursus arctos) during Hibernation
  10. 8570
    “…Nearly the same gene module was identified in prophages of B. thuringiensis serovar monterrey BGSC 4AJ1 and B. cereus Rock4-2. These findings suggest that MZTP02 can be shuttled between genomes of other bacteriophages and prophages, leading to the formation of chimeric genomes. …”
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    Novel Bacteriophages Containing a Genome of Another Bacteriophage within Their Genomes
  11. 8571
    “…Methylated DNA immunoprecipitation-sequencing (MeDIP-seq) was used to investigate the genome-wide DNA methylation pattern in high and low tails of Recessive White Rock (WRR(h); WRR(l)) and that of Xinhua Chickens (XH(h); XH(l)) at 7 weeks of age. …”
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    Comparison of the Genome-Wide DNA Methylation Profiles between Fast-Growing and Slow-Growing Broilers
  12. 8572
    “…Encounters of colonies with neighbors of a different morphotype or species reveal relationships of dominance, cooperation, or submission; multiple interactions can be summarized in "rock – paper – scissors" network of interrelationships. …”
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    Developmental plasticity of bacterial colonies and consortia in germ-free and gnotobiotic settings
  13. 8573
    “…Here we investigate the first and the second prerequisite in allopatric chromatically differentiated lineages of the rock-dwelling cichlid Tropheus spp. from southern Lake Tanganyika (Central Africa). …”
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    Contrasting parasite communities among allopatric colour morphs of the Lake Tanganyika cichlid Tropheus
  14. 8574
    “…Nine novel functional miRNAs (hsa-miR-129, -136, -145, -155, -181b, -342-5p, -342-3p, -376a/b) in GBM cell lines were validated for their importance in glioma cell growth, and similar effects for six target genes (ROCK1, RHOA, MET, CSF1R, EIF2AK1, FGF7) of these miRNAs were shown functionally. …”
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    Functional Profiling of Precursor MicroRNAs Identifies MicroRNAs Essential for Glioma Proliferation
  15. 8575
    “…Inactivation of DLC1 results in hyper-activated Rho/ROCK signaling and is implicated in actin cytoskeleton reorganization to promote cancer metastasis. …”
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    EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers
  16. 8576
    por Kampen, Helge, Werner, Doreen
    Publicado 2014
    “…The Asian bush or rock pool mosquito Aedes japonicus japonicus is one of the most expansive culicid species of the world. …”
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    Out of the bush: the Asian bush mosquito Aedes japonicus japonicus (Theobald, 1901) (Diptera, Culicidae) becomes invasive
  17. 8577
    “…We use as a case study the Australian southern rock lobster Jasus edwardsii fishery, which is challenged by a number of climate change drivers such as impacts on recruitment and growth due to changes in large-scale and local oceanographic features. …”
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    A Quantitative Metric to Identify Critical Elements within Seafood Supply Networks
  18. 8578
    “…The over-expression of miRNA-122 also caused cytoskeleton disruption, RhoA/Rock pathway inactivation, enhanced cell adhesion, and suppression of migration and invasion of Sk-hep-1 and Bel-7402 cells, whereas, these effects could be reversed through miR-122 inhibition. …”
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    MicroRNA-122 Triggers Mesenchymal-Epithelial Transition and Suppresses Hepatocellular Carcinoma Cell Motility and Invasion by Targeting RhoA
  19. 8579
    “…Gaber) at UTHSC until 2007 and by Nephropath(TM) (Little Rock, AR, USA) thereafter. Staining for the mesangial deposits was considered negative when intensity was trace or less, and positive at greater intensity. …”
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    Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathy
  20. 8580
    “…It grows mostly in the rock crevices on slopes. Juice from the rhizome of CA has been used to treat peptic ulcer. …”
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    Evaluation of in vitro and in vivo Biological Activities of Cheilanthes albomarginata Clarke
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