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8581por Li, Tian-Fu, Wu, Qiu-Yue, Zhang, Cui, Li, Wei-Wei, Zhou, Qing, Jiang, Wei-Jun, Cui, Ying-Xia, Xia, Xin-Yi, Shi, Yi-Chao“…No mutation was detected in the coding region and exon/intron boundaries of the RSPO1, DAX1, SOX9, SOX3, SOX10, ROCK1, and DMRT genes, and no copy number variation in the whole genome sequence was found. …”
Publicado 2014
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8582por Duggirala, Aparna, Kimura, Tomomi E., Sala-Newby, Graciela B., Johnson, Jason L., Wu, Yih-Jer, Newby, Andrew C., Bond, Mark“…Inhibiting RhoA activity, which regulates actin-polymerisation, by cAMP-elevation or pharmacologically with C3-transferase, or inhibiting its downstream kinase, ROCK, with Y27632, significantly inhibited CCN1 expression. …”
Publicado 2015
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8583por Weinheimer, Isabel, Jiu, Yaming, Rajamäki, Minna-Liisa, Matilainen, Olli, Kallijärvi, Jukka, Cuellar, Wilmer J., Lu, Rui, Saarma, Mart, Holmberg, Carina I., Jäntti, Jussi, Valkonen, Jari P. T.“…Certain RNA and DNA viruses that infect plants, insects, fish or poikilothermic animals encode Class 1 RNaseIII endoribonuclease-like proteins. dsRNA-specific endoribonuclease activity of the RNaseIII of rock bream iridovirus infecting fish and Sweet potato chlorotic stunt crinivirus (SPCSV) infecting plants has been shown. …”
Publicado 2015
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8584“…RhoA associated kinase (ROCK) activity was also profoundly enhanced (P < 0.05). …”
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8585“…Also , to find out diagnostic value of fluorescence imaging (VELscope® system , LED Dental Inc., White Rock, B.C.) and salivary protoporphyrin IX (PX) in oral precancerous and cancerous lesions. …”
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8586“…Shrub cover was positively related to both mammal abundance and richness, and availability of rock crevices, ground vegetation cover and spatial extent of ≥4 years unburnt habitat were all positively associated with at least some of the mammal species modelled. …”
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8587“…CONCLUSIONS: The phylogenetic and population structures are intrinsically associated with stable rock surfaces and landscape rearrangements, such as the establishment of drainage basins located to the northern and southern distribution ranges. …”
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8588por Proctor, B P, Mitchell, T M, Hirth, G, Goldsby, D, Zorzi, F, Platt, J D, Di Toro, G“…To investigate differences in the frictional behavior between initially bare rock surfaces of serpentinite and powdered serpentinite (“gouge”) at subseismic to seismic slip rates, we conducted single-velocity step and multiple-velocity step friction experiments on an antigorite-rich and lizardite-rich serpentinite at slip rates (V) from 0.003 m/s to 6.5 m/s, sliding displacements up to 1.6 m, and normal stresses (σ(n)) up to 22 MPa for gouge and 97 MPa for bare surfaces. …”
Publicado 2014
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8589por Ouyang, Hongjia, He, Xiaomei, Li, Guihuan, Xu, Haiping, Jia, Xinzheng, Nie, Qinghua, Zhang, Xiquan“…To investigate the function of miRNAs in chicken growth, breast muscle tissues of the two-tail samples (highest and lowest body weight) from Recessive White Rock (WRR) and Xinghua Chickens (XH) were performed on high throughput small RNA deep sequencing. …”
Publicado 2015
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8590“…The Asian shore crab, Hemigrapsus sanguineus, and small individuals of the green crab, Carcinus maenas, were observed only in the treatments of rocks and mesh bag plus rocks. Most green crabs were small (<6 mm in carapace width) whereas H. sanguineus occurred in a wide range of sizes. …”
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8591“…We found 32 bird species, all native with the exception of House Sparrow and Rock Pigeon. The most common species were House Sparrow and Chilean Swallow. …”
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8592por Tschegg, Cornelius, Bizimis, Michael, Schneider, David, Akinin, Vyacheslav V., Ntaflos, Theodoros“…We present mineral and bulk rock geochemical data as well as Sr–Nd–Pb–Hf isotopes of the alkaline suite of rocks combined with new precise K–Ar and (40)Ar/(39)Ar dating, and discuss an integrated tectono-magmatic model for the Chersky belt. …”
Publicado 2011
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8593por Miettinen, Hanna, Kietäväinen, Riikka, Sohlberg, Elina, Numminen, Mikko, Ahonen, Lasse, Itävaara, Merja“…Pyhäsalmi mine in central Finland provides an excellent opportunity to study microbial and geochemical processes in a deep subsurface crystalline rock environment through near-vertical drill holes that reach to a depth of more than two kilometers below the surface. …”
Publicado 2015
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8594por Akhtar, Saghir, Chandrasekhar, Bindu, Attur, Sreeja, Dhaunsi, Gursev S., Yousif, Mariam H. M., Benter, Ibrahim F.“…Ang-(1–7) or AG825 treatment inhibited diabetes-induced phosphorylation of ErbB2 receptor at tyrosine residues Y1221/22, Y1248, Y877, as well as downstream signaling via ERK1/2, p38 MAPK, ROCK, eNOS and IkB-α in the mesenteric vascular bed. …”
Publicado 2015
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8595por Zheng, Yu-Liang, Sun, Yang-Peng, Zhang, Hong, Liu, Wen-Jing, Jiang, Rui, Li, Wen-Yu, Zheng, You-Hua, Zhang, Zhi-Guang“…The dissociated cells were then plated into Matrigel-coated culture plate with alpha minimum essential medium supplemented with 10% fetal bovine serum, 1× Glutamax, and the ROCK inhibitor Y-27632. Cells were then passaged in standard cell culture plates with alpha minimum essential medium supplemented with 10% fetal bovine serum and 1× Glutamax. …”
Publicado 2015
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8596por Schwickert, Alexander, Weghake, Esther, Brüggemann, Kathrin, Engbers, Annika, Brinkmann, Benjamin F., Kemper, Björn, Seggewiß, Jochen, Stock, Christian, Ebnet, Klaus, Kiesel, Ludwig, Riethmüller, Christoph, Götte, Martin“…Supported by transcriptomic Affymetrix array analysis and confirmatory investigations at the mRNA and protein level, we demonstrate that overexpression of miR-142-3p in MDA-MB-231, MDA-MB-468 and MCF-7 breast cancer cells leads to downregulation of WASL (Wiskott-Aldrich syndrome-like, protein: N-WASP), Integrin-αV, RAC1, and CFL2, molecules implicated in cytoskeletal regulation and cell motility. ROCK2, IL6ST, KLF4, PGRMC2 and ADCY9 were identified as additional targets in a subset of cell lines. …”
Publicado 2015
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8597por Fernandez, Serena, Risolino, Maurizio, Mandia, Nadia, Talotta, Francesco, Soini, Ylermi, Incoronato, Mariarosaria, Condorelli, Gerolama, Banfi, Sandro, Verde, Pasquale“…These changes correlate with the miR-340-mediated inhibition of previously validated (MET and ROCK1) and potentially novel (RHOA and CDH1) miR-340 target transcripts. …”
Publicado 2014
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8598“…Y-27632 is a specific inhibitor of Rho-associated protein kinases (ROCKs), which are downstream effectors of Rho GTPase. …”
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8599por Warrant, Eric, Frost, Barrie, Green, Ken, Mouritsen, Henrik, Dreyer, David, Adden, Andrea, Brauburger, Kristina, Heinze, Stanley“…Once in the Alps (from the end of September), Bogong moths seek out the shelter of selected and isolated high ridge-top caves and rock crevices (typically at elevations above 1800 m). …”
Publicado 2016
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8600por Jangir, Yamini, French, Sarah, Momper, Lily M., Moser, Duane P., Amend, Jan P., El-Naggar, Mohamed Y.“…Here, we report the electrochemical enrichment of microorganisms from a deep fractured-rock aquifer in Death Valley, CA, USA. In experiments performed in mesocosms containing a synthetic medium based on aquifer chemistry, four working electrodes (WEs) were poised at different redox potentials (272, 373, 472, 572 mV vs. …”
Publicado 2016
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