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8741por Abudula, Maidinaimu, Fan, Xiaodan, Zhang, Jing, Li, Jiajie, Zhou, Xiaoming, Chen, Yichen“…In ectopic stromal cells, ERa receptors stimulated the RhoA/Rock-2/MSN pathway. We discovered that downregulating exosomal moesin reduced NSC migration (about 3-fold change) and MMP9 expression (about 2-fold change). …”
Publicado 2022
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8742por Feng, Xue-Feng, Lei, Jian-Feng, Li, Man-Zhong, Zhan, Yu, Yang, Le, Lu, Yun, Li, Ming-Cong, Zhuang, Yu-Ming, Wang, Lei, Zhao, Hui“…Notably, TMP upregulated GAP-43 and SYN and enhanced axonal guidance cues such as Netrin-1/DCC and Slit-2/Robo-1 but downregulated intrinsic growth-inhibitory signals NogoA/NgR/RhoA/ROCK-2. Taken together, our data indicated that TMP facilitated poststroke axonal remodeling and motor functional recovery. …”
Publicado 2022
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8743por Dose, Wesley M., Temprano, Israel, Allen, Jennifer P., Björklund, Erik, O’Keefe, Christopher A., Li, Weiqun, Mehdi, B. Layla, Weatherup, Robert S., De Volder, Michael F. L., Grey, Clare P.“…Higher lattice oxygen release with EC-containing electrolytes is coupled with higher cathode interfacial impedance, a thicker oxygen-deficient rock-salt surface reconstruction layer, more electrolyte solvent and salt breakdown, and higher amounts of transition metal dissolution. …”
Publicado 2022
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8744por Bell, Emma, Lamminmäki, Tiina, Alneberg, Johannes, Qian, Chen, Xiong, Weili, Hettich, Robert L., Frutschi, Manon, Bernier-Latmani, Rizlan“…Zerovalent sulfur in the groundwater may derive from abiotic rock interactions, or from a non-obligate syntrophy with Methanoperedens, potentially linking methane and sulfur cycles in Olkiluoto groundwater. …”
Publicado 2022
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8745“…The proposed method based on Bayesian theory can better use the detection information to recognize and understand the rock and soil in advance; hence, the evaluation results are more reliable and consistent with the actual engineering state.…”
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8746por Ghanchi, Faruque, Bourne, Rupert, Downes, Susan M., Gale, Richard, Rennie, Christina, Tapply, Ian, Sivaprasad, Sobha“…This review delivers an overview of anti-VEGF agents with longer durations of action, DARPins, bispecific anti-VEGF/Ang2 therapies, anti-PDGF and anti-integrin therapy, Rho-kinase inhibitors, the Port Delivery System, steroids, gene therapy for retina and uveitis, and for glaucoma, ROCK inhibitors, implants and plugs, and SLT laser and MIGS. …”
Publicado 2022
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8747por Pandit, P., Saini, Atul, Chidambaram, Sabarathinam, Kumar, Vinod, Panda, Banjarani, Ramanathan, A. L., Sahu, Netrananda, Singh, A. K., Mehra, Rohit“…Speciation results suggested that dissolution of primary U mineral, carnotite [K(2)(UO(2))(2)(VO(4))(2)·3H(2)O] governs the enrichment. Water–rock interaction and evaporation are found the major hydrogeochemical processes controlling U mineralization. …”
Publicado 2022
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8748por Karátson, Dávid, Biró, Tamás, Portnyagin, Maxim, Kiss, Balázs, Paquette, Jean-Louis, Cseri, Zoltán, Hencz, Mátyás, Németh, Károly, Lahitte, Pierre, Márton, Emő, Kordos, László, Józsa, Sándor, Hably, Lilla, Müller, Samuel, Szarvas, Imre“…However, unlike the seemingly similar AD 79 Vesuvius eruption that buried Pompeii by hot pyroclastic density currents, the presence of fallen but uncharred tree trunks, branches, and intact leaves in the basal pyroclastic deposits at Ipolytarnóc as well as rock paleomagnetic properties indicate a low-temperature pyroclastic event, that superbly preserved the coastal habitat, including unique fossil tracks.…”
Publicado 2022
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8749por Hu, Xiaoyi, Wang, Qian, Zhao, Hui, Wu, Wenhui, Zhao, Qinhua, Jiang, Rong, Liu, Jinming, Wang, Lan, Yuan, Ping“…The abnormal expression of RhoA, ROCK2, Rac1 and c‐Jun in the lungs of MCT‐PH rats was inhibited by E(2) and miR‐21‐5p antagonist. …”
Publicado 2022
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8750“…Finally, we used the large-sized physical simulation device for tight oil WIHP that can bear high temperature and high pressure and a nuclear magnetic resonance instrument to conduct experiments of five cycles of constant pressure WIHP (CWIHP) with WIPs of 25, 32.5, and 40 MPa and step-by-step pressure rising WIHP (SWIHP) (the WIP was 25, 30, 33, 37, and 40 MPa in order) and obtained the liquid production law and mechanism of tight volcanic rock (TVR) under CWIHP and SWIHP. The result shows that under the CWIHP mode, the RF of TVR has a good power-law-positive correlation with the WIP. …”
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8751“…To overcome the limitation of the " limited outlook " of water-conducting fracture zone investigation, the spatial development characteristics of roof fissures in coal seam mining were determined by on-site " the underground - ground" combined microseismic monitoring and follow-up monitoring, and the development of overlying rock fracture under the large depth of burial was concluded. …”
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8752Assessing the Clinical Robustness of Digital Health Startups: Cross-sectional Observational Analysis“…METHODS: A cross-sectional observational analysis was conducted using company data from the Rock Health Digital Health Venture Funding Database, the US Food and Drug Administration, and the US National Library of Medicine. …”
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8753“…Phosphorus (P) is one of the most limiting macronutrients for agricultural productivity. Given that phosphate rock is a finite resource, coupled with the increasing difficulty in its extraction and geopolitical fragility in supply, it is anticipated that both economic and environmental costs of P fertilizer will greatly increase. …”
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8754por Wang, Di, Li, Quan, Pan, Chun-Shui, Yan, Li, Sun, Kai, Wang, Xiao-Yi, Anwaier, Gulinigaer, Liao, Qian-Zan, Xie, Ting-Ting, Fan, Jing-Yu, Huo, Xin-Mei, Wang, Yuan, Han, Jing-Yan“…Quantitative proteomics discovered that the effect of YPF implicated the Siah2-ubiquitin-proteasomal pathway, Gng12-PAK1-MLCK, and RhoA/ROCK, which was further confirmed by Western blot. …”
Publicado 2022
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8755por Vereide, Vegard, Andersen, Vidar, Hermans, Espen, Kalland, Jarle, Saeterbakken, Atle Hole, Stien, Nicolay“…Seventy-eight male climbers were recruited and divided into groups based on the International Rock Climbing Research Association (IRCRA) numerical (1–32) grading system (intermediate (10–17) group (IG; n = 28)), advanced (18–23) group (AG; n = 30) and elite (24–27) group (EG; n = 20). …”
Publicado 2022
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8756por Adnan, Muhammad, Fahad, Shah, Saleem, Muhammad Hamzah, Ali, Baber, Mussart, Maria, Ullah, Rafi, Amanullah Jr, Arif, Muhammad, Ahmad, Manzoor, Shah, Wajid Ali, Romman, Muhammad, Wahid, Fazli, Wang, Depeng, Saud, Shah, Liu, Ke, Harrison, Matthew Tom, Wu, Chao, Danish, Subhan, Datta, Rahul, Muresan, Crina Carmen, Marc, Romina Alina“…Therefore, we performed pot experiment to study the role of PSB in nullifying antagonistic effects of liming (4.78, 10, 15 and 20%) on P availability from poultry manure (PM), farm yard manure (FYM), single super phosphate (SSP) and rock phosphate (RP) in alkaline soils. PSB inoculation improved wheat growth, P availability and stimulated soil acidification over control regardless of P sources and lime levels. …”
Publicado 2022
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8757por Wilmeth, Dylan T., Myers, Kimberly D., Lalonde, Stefan V., Mänd, Kaarel, Konhauser, Kurt O., Grandin, Prisca, van Zuilen, Mark A.“…Patterns of silica precipitation in El Tatio microbial communities show that the preservation potential of silicifying mats in the rock record is strongly dependent on aqueous silica concentrations.…”
Publicado 2021
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8758por Blanco-Vargas, Andrea, Chacón-Buitrago, María A., Quintero-Duque, María C., Poutou-Piñales, Raúl A., Díaz-Ariza, Lucía A., Devia-Castillo, Carlos A., Castillo-Carvajal, Laura C., Toledo-Aranda, Daniel, da Conceição de Matos, Christiano, Olaya-González, Wilmar, Ramos-Monroy, Oswaldo, Pedroza-Rodríguez, Aura M.“…The results indicated that BC(500) is suitable as organic support or solid matrix to maintain the viability of PSB able to solubilise P from phosphate rock (PR). The biofertilizer (BC(500)/PSB) allows increasing germination, seedling growth, nutrient assimilation, and growth of Allium cepa L., because PSB immobilised on BC(500) promoted nutrient mobilisation, particularly P, during cultivation of Allium cepa L., at pots scale. …”
Publicado 2022
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8759“…This research, although needing further study, suggests that industrial minerals could be a new, safe (“found in toothpaste”) and persistent (“it’s rock”) alternative to chemical pesticides to control ticks. …”
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8760“…We approached these issues by developing a novel style-based deep generative adversarial network (GAN) model, PetroGAN, to create the first realistic synthetic petrographic datasets across different rock types. PetroGAN adopts the architecture of StyleGAN2 with adaptive discriminator augmentation (ADA) to allow robust replication of statistical and esthetical characteristics and improve the internal variance of petrographic data. …”
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