“…ROCK is associated with cancer progression, and ROCK protein expression is elevated in several types of cancer. …”
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“…For centuries, rocking has been used to promote sleep in babies or toddlers. …”
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“…More specifically, based on autoethnography and interviews with elite climbers in Norway, we explore to what extent risk-taking is built into the value system of climbing, and to what degree risk-taking leads to peer-recognition and credibility within rock climbing communities. We find that there is a clear connection between risk-taking and recognition in the value system of climbing. …”
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“…Here, we first predicted in silico and later confirmed in vitro that UPF 1069, a known bioactive poly(ADP-ribose) polymerase-1/2 (PARP1/2) molecule, and hydroxyfasudil, a known bioactive Rho-associated protein kinase-1/2 (ROCK1/2) molecule, have low-micromolar cross-affinity for ROCK1/2 and PARP1/2, respectively. …”
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“…We investigated the interaction of silica nanostructured particles and sandstone rock using various experimental approaches, such as fluid compatibility, batch sorption and single-phase core-floods. …”
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“…The largest observed rock movement involved >60 rocks on December 20, 2013 and some instrumented rocks moved up to 224 m between December 2013 and January 2014 in multiple move events. …”
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“…Exogenous expression of ROCK1 or ROCK2 in 143B-miR-144 cells partially restored miR-144-inhibited cell proliferation and invasion. …”
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“…Rock damage is one of the key factors in the design and model choice of mining machinery. …”
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“…When the rock content is more than 30%, the streaming potential coupling coefficient decreases with the increases in rock content. …”
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“…The mechanical properties of the broken rock were clearly affected by the original rock strength of the roof. …”
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“…This article deals with the problem of predicting the brittle fracture of rocks and similar materials, which can also include frozen sandy soils. …”
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“…It is very necessary to study the mechanism of rock burst, which is related to the safe construction of many geotechnical projects. …”
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“…The development of deep geotechnical engineering is restricted by the complex geological conditions of deep rock masses and the unknown creep mechanism of rock in water-rich environments. …”
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“…Here, we used immortalized microglial (IMG) cells and primary microglia (PMg) to understand the roles of the GTPase Ras homolog gene family member A (RhoA) and its downstream targets Rho-associated coiled-coil-containing protein kinases 1 and 2 (ROCK1 and ROCK2) in neuroinflammation. We used a pan-kinase inhibitor (Y27632) and a ROCK1- and ROCK2-specific inhibitor (RKI1447) to mitigate a lipopolysaccharide (LPS) challenge. …”
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“…To overcome this problem, this study aims to extract a new rock fragmentation index (RFI) that can reflect RC from real-time rock fragmentation data of the TBM. …”
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“…According to the geological characteristics of Xinjiang Ili mine in western area of China, a physical model of interstratified strata composed of soft rock and hard coal seam was established. Selecting the tunnel position, deformation modulus, and strength parameters of each layer as influencing factors, the sensitivity coefficient of roadway deformation to each parameter was firstly analyzed based on a Mohr-Columb strain softening model and nonlinear elastic-plastic finite element analysis. …”
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“…In rocks or rock-like materials, the constituents, e.g. quartz, calcite and biotite, as well as the microdefects have considerably different mechanical properties that make such materials heterogeneous at different degrees. …”
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“…Fluid injection into rocks is increasingly used for energy extraction and for fluid wastes disposal, and can trigger/induce small- to medium-scale seismicity. …”
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