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  1. 1121
    “…The contraction was dependent on ROCK1 activity as the ROCK inhibitor Y27632 dose-dependently blocked contraction in fibroblasts from COPD patients. …”
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    Enhanced ROCK1 dependent contractility in fibroblast from chronic obstructive pulmonary disease patients
  2. 1122
    “…The aim of this study was to investigate the role of the Rho/Rho associated coiled coil-forming protein kinase (Rock) signaling pathway in the pathogenesis of ischemic myocardial fibrosis (MF) in rats. …”
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    The role of the Rho/Rock signaling pathway in the pathogenesis of acute ischemic myocardial fibrosis in rat models
  3. 1123
    “…The pharmacological blockade of ROCK, a key signaling component for myelin-associated growth inhibitors, reduced axonal U-turns and potentiated AAV2.Stat3-ca-induced regeneration. …”
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    Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve
  4. 1124
    “…In this study, we describe the bacterial diversity of the rock-water interface in Lake Tawani(P) using culture-independent Bacterial Tag Encoded FLX Amplicon Pyrosequencing (bTEFAP), clone library construction, and culture-based analysis targeting the eubacterial 16S rRNA gene. …”
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    Bacterial diversity of the rock-water interface in an East Antarctic freshwater ecosystem, Lake Tawani(P)(†)
  5. 1125
    “…Most salt rock has interbed of mudstone in China. Owing to the enormous difference of mechanical properties between the mudstone interbed and salt rock, the stress-strain and creep behaviors of salt rock are significantly influenced by neighboring mudstone interbed. …”
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    Numerical Simulation on Open Wellbore Shrinkage and Casing Equivalent Stress in Bedded Salt Rock Stratum
  6. 1126
    por Zhao, Zi-Fu, Dai, Li-Qun, Zheng, Yong-Fei
    Publicado 2013
    “…Findings of coesite and microdiamond in metamorphic rocks of supracrustal protolith led to the recognition of continental subduction to mantle depths. …”
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    Postcollisional mafic igneous rocks record crust-mantle interaction during continental deep subduction
  7. 1127
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    Airway management in cervical spine ankylosing spondylitis: Between a rock and a hard place
  8. 1128
    “…OBJECTIVES: The RhoA/ROCK pathway contributes to diabetic cardiomyopathy in part by promoting the sustained activation of PKCβ2 but the details of their interaction are unclear. …”
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    Complex Regulation of PKCβ2 and PDK-1/AKT by ROCK2 in Diabetic Heart
  9. 1129
    “…The current study sought to delineate the possible involvement of the RhoA/ROCK pathway in leptin-mediated cytoskeleton reorganization in nucleus pulposus cells. …”
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    Leptin Activates RhoA/ROCK Pathway to Induce Cytoskeleton Remodeling in Nucleus Pulposus Cells
  10. 1130
    “…However, the effect of ROCK in Rb is largely unknown. METHODS: ROCK-1 and ROCK-2 mRNA expression in Y79 cell lines were examined by RT-PCR. …”
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    The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells
  11. 1131
    “…Knockdown of ROCK1 and ROCK2 revealed their additive roles in centrosome integrity. …”
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    Multimodal Effects of Small Molecule ROCK and LIMK Inhibitors on Mitosis, and Their Implication as Anti-Leukemia Agents
  12. 1132
    “…The Rho/ROCK/LIMK pathway is central for the mediation of repulsive environmental signals in the central nervous system. …”
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    ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS
  13. 1133
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    Predator-Prey Interactions between Shell-Boring Beetle Larvae and Rock-Dwelling Land Snails
  14. 1134
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    Possible involvement of rho kinase 1 (rock 1) in cecal ligation and puncture-induced sepsis
  15. 1135
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    Microsatellite loci for Orthophytum ophiuroides (Bromelioideae, Bromeliaceae) species adapted to neotropical rock outcrops(1)
  16. 1136
    “…Indeed, an enhanced activation of RhoA and ROCK has been reported in the spinal cord of an SMA mouse model. …”
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    ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targets
  17. 1137
    “…Herein, we demonstrate an alternative strategy that avoids disruption of cell–cell junctions and instead activates Ras homologue gene family A (RhoA)–Rho-associated protein kinase (ROCK)–canonical bone morphogenic protein signaling to reprogram adult human corneal endothelial cells to neural crest–like progenitors via activation of the miR302b-Oct4-Sox2-Nanog network. …”
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    Activation of RhoA-ROCK-BMP signaling reprograms adult human corneal endothelial cells
  18. 1138
    “…Live bacteria and archaea have been isolated from several rock salt deposits of up to hundreds of millions of years of age from all around the world. …”
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    Halophilic Archaea Cultivated from Surface Sterilized Middle-Late Eocene Rock Salt Are Polyploid
  19. 1139
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    ROCK Inhibitor Is Not Required for Embryoid Body Formation from Singularized Human Embryonic Stem Cells
  20. 1140
    “…Inhibitors of Rho kinase (ROCK) cause stellation of cultured 2D astrocytes, increased L-glutamate transport, augmented G-actin, and elevated expression of BDNF and anti-oxidant genes. …”
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    Transcriptomic analysis and 3D bioengineering of astrocytes indicate ROCK inhibition produces cytotrophic astrogliosis
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