“…Therefore, curcumin as a ROCK signalling inhibitor has the potential to prevent atherogenesis via multiple ways.…”
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“…S oft rock and sand were combined using the ratio (v/v) of 0:1 (CK), 1:5 (S1), 1:2 (S2), and 1:1 (S3). …”
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“…The rho-associated coiled-coil–containing protein kinase-2 (ROCK2) signaling pathway regulates the Th17/regulatory T cells balance and controls profibrotic pathways. …”
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“…Here, for the first time, we carry out an integrated study combining in situ analysis of zircon U–Th–Pb and Hf–O isotopes, and trace element compositions of zircons from the volcanic rocks from the southernmost part of the OT. We found that the young (< 100 ka) zircons in these volcanic rocks have old (108 Ma to 2.7 Ga) inherited cores, which were captured as the magma ascended through the rifting continental crust. …”
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“…Pre-existing cracks and associated filling materials cause the significant heterogeneity of natural rocks and rock masses. The induced heterogeneity changes the rock properties. …”
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“…We report here an amplicon sequencing characterization of rocks collected from Joshua Tree National Park (JTNP), USA.…”
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“…The La-Th-Sc, Th-Sc-Zr/10 and La/Th-Hf data of the silt- and sandstones of the lower Zhoutian Formation show that its provenance was mainly a mixture of felsic upper crust sediments and older sedimentary rocks.…”
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“…The present work investigated the differences in the composition and internal microstructure of four types gypsum rock—fiber gypsum, transparent gypsum, alabaster, and ordinary gypsum by X-ray fluorescence spectrometry, X-ray diffraction, scanning electron microscope and Brazilian split test, and analyzed its effects on the tensile strength and fracture characteristics of gypsum rock. …”
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“…This novel framework, which can reveal the control mechanism of brittle rock heterogeneity on continuous-discontinuous trans-scale fracture process and microscopic rock behaviour, provides an effective technology and numerical analysis method for characterizing rock meso-structure. …”
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“…Problems concerning the influence of the geometric parameters of an undercutting anchor on the range of the failure zone of rock medium during the pulling out of the anchor constitute one of the aspects that arouse the interest of authors due to attempts to use undercutting anchors in the process of rock lump separation. …”
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“…Ten male rock climbers (Rock Climbing Group, RCG = 10) and ten physically active men (Control Group, CG = 10) performed, on three separate occasions, a familiarization session with procedures adopted during MBboard-1RM testing and two experimental trials (i.e., test and retest) to determine the construct validity and reliability of the MBboard during unilateral seated cable row exercise. …”
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“…Here, we examine how self-selected speed in the Svalbard rock ptarmigan is affected by snow supportiveness and subsequent footprint depth measured using thin-blade penetrometry and 3D photogrammetry, respectively. …”
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“…Proper mechanical model selection is critical in tunnel support design and stability analysis, especially to reflect the creep and strain-softening behavior of soft rock. We present a coupled nonlinear Burgers strain-softening (NBSS) model and numerical calculation method to investigate the coupled effects of creep and strain-softening of soft rock tunnels. …”
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“…Digital rock is an emerging area of rock physics, which involves scanning reservoir rocks using X-ray micro computed tomography (XCT) scanners and using it for various petrophysical computations and evaluations. …”
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“…Remarkably, TAGLN, encoding an actin cross-linking/gelling protein, was identified as a potent mechanosensitive gene that could form a regulation loop with Src activation reacting to environmental stiffness, thus mediating stiffness-regulated OC progression through regulating RhoA/ROCK pathway. CONCLUSIONS: These data demonstrate that targeting extra-cellular matrix (ECM) stiffness could probably hamper OC progression, and of note, targeting TAGLN might provide promising clinical therapeutic value for OC therapy. …”
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“…Paralytic shellfish toxins (PST) are found in the hepatopancreas of Southern Rock Lobster Jasus edwardsii from the east coast of Tasmania in association with blooms of the toxic dinoflagellate Alexandrium catenella. …”
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“…Whereas we confirmed the presence of these genes in known nitrogen-fixing and/or rock weathering organisms (e.g., Nostoc, Burkholderia), in this study, we also detected organisms that, even if often found in soil and proglacial systems, have never been related to nitrogen-fixing or rock weathering processes before (e.g., Fimbriiglobus, Streptomyces). …”
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“…Based on the notched borehole and timing sequence control (TSC) fracture blasting method, this paper studies the effects of different borehole shapes on the degree of damage of the surrounding rock and profile flatness of the rock anchor beams and the effects of different filled joint characteristics on the blasting crack propagation rules. …”
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“…But these inferences derive from only a few elements, none of which define rock type. We thus present the first estimates of rock types on exoplanets that once orbited polluted white dwarfs—stars whose atmospheric compositions record the infall of formerly orbiting planetary objects—examining cases where Mg, Si, Ca and Fe are measured with precision. …”
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