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  1. 1641
    “…Knocking down ROCK1 expression using a ROCK1-specific siRNA also significantly abrogated AT-101-mediated apoptosis. …”
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    RhoA/ROCK/PTEN signaling is involved in AT-101-mediated apoptosis in human leukemia cells in vitro and in vivo
  2. 1642
    Publicado 2014
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    Correction: Downregulation of ROCK2 through Nanocomplex Sensitizes the Cytotoxic Effect of Temozolomide in U251 Glioma Cells
  3. 1643
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    Properties of Halococcus salifodinae, an Isolate from Permian Rock Salt Deposits, Compared with Halococci from Surface Waters
  4. 1644
    “…The main factors of the developmental environment of marine source rocks in continental margin basins have their specificality. …”
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    Palaeoenvironment and Its Control on the Formation of Miocene Marine Source Rocks in the Qiongdongnan Basin, Northern South China Sea
  5. 1645
    “…RESULTS: The mTOR, ZEB1 and ROCK1 mainly expressed in alveolar epithelial cells of UIP lungs. …”
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    Clinical significance of mTOR, ZEB1, ROCK1 expression in lung tissues of pulmonary fibrosis patients
  6. 1646
    “…Determination of the relationships between groups of quantities describing pore space of rock formation was presented as the basis for permeability prediction and for relationships extrapolation into interesting areas.…”
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    Rock Reservoir Properties from the Comprehensive Interpretation of Nuclear Magnetic Resonance and Mercury Injection Porosimetry Laboratory Results
  7. 1647
    “…The present study aims to characterize the fatty acid derivatives from the Sydney rock oyster Saccostrea glomerata and its pharmacological activities. …”
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    Studies on the antimicrobial potential and structural characterization of fatty acids extracted from Sydney rock oyster Saccostrea glomerata
  8. 1648
    “…Most of the glial growth inhibiting factors converge onto the Rho/ROCK signaling pathway in neurons. Although conditions in the injured nervous system are clearly different from those during neurite outgrowth in vitro, here we use a chemical approach to manipulate Rho/ROCK signalling with small-molecule agents to encourage neurite outgrowth in cell culture. …”
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    Enhanced Neurite Outgrowth of Human Model (NT2) Neurons by Small-Molecule Inhibitors of Rho/ROCK Signaling
  9. 1649
    “…Cryptosporidium, a parasitic protozoan genus comprising host-adapted and host-specific species, was used as an indicator of parasite movement between populations of a threatened marsupial, the brush-tailed rock-wallaby (Petrogale penicillata). PCR screening of faecal samples (n = 324) from seven wallaby populations across New South Wales, identified Cryptosporidium in 7.1% of samples. …”
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    Diversity of Cryptosporidium in brush-tailed rock-wallabies (Petrogale penicillata) managed within a species recovery programme
  10. 1650
    “…Although LPA in this concentration did not induce transcriptional activity of β-catenin, it promoted the activation of Rho and STAT-3. Moreover, ROCK and STAT-3 inhibitors prevented LPA-induced proliferation, but ROCK inhibition did not prevent STAT-3 activation. …”
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    LPA Induces Colon Cancer Cell Proliferation through a Cooperation between the ROCK and STAT-3 Pathways
  11. 1651
    “…Importantly, we found that, in BMSCs, inhibition of ROCK significantly inhibits MCP-1-induced chemotactic migration, in contrast to previous reports in other systems. …”
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    ROCK activity and the Gβγ complex mediate chemotactic migration of mouse bone marrow-derived stromal cells
  12. 1652
    “…FMNL2 could activate Rho/ROCK pathway, and required ROCK to promote CRC cell invasion. …”
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    Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer
  13. 1653
    “…The GTPases belonging to the Rho family control the actin cytoskeleton rearrangements needed for particle internalization during phagocytosis. ROCK and mDia1 are downstream effectors of RhoA, a GTPase involved in that process. …”
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    Coxiella burnetii Phagocytosis Is Regulated by GTPases of the Rho Family and the RhoA Effectors mDia1 and ROCK
  14. 1654
    “…Although Fasudil inhibited both ROCK I and ROCK II, FSD-C10 more selectively suppressed ROCK II, but not ROCK I, which may be related to vasodilation insensitivity and animal mortality. …”
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    FSD-C10: A more promising novel ROCK inhibitor than Fasudil for treatment of CNS autoimmunity
  15. 1655
    “…Ripasudil hydrochloride hydrate (K-115), a specific Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor, was the first ophthalmic solution developed for the treatment of glaucoma and ocular hypertension in Japan. …”
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    Effects of K-115 (Ripasudil), a novel ROCK inhibitor, on trabecular meshwork and Schlemm’s canal endothelial cells
  16. 1656
    “…In this study, we investigated the potential role of Fyn/ROCK signaling and its interactions with paxillin. …”
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    Fyn Mediates High Glucose-Induced Actin Cytoskeleton Reorganization of Podocytes via Promoting ROCK Activation In Vitro
  17. 1657
    “…The Pyrenean rock ptarmigan (Lagopus muta pyrenaica) is the southernmost subspecies of the species in Europe and is considered threatened as a consequence of changes in landscape, human pressure, climate change, and low genetic diversity. …”
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    Influence of Snowmelt Timing on the Diet Quality of Pyrenean Rock Ptarmigan (Lagopus muta pyrenaica): Implications for Reproductive Success
  18. 1658
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    Stuck between a rock and a hard place: the work situation for nurses as leaders in municipal health care
  19. 1659
    “…Lingunite nanocrystals and amorphous plagioclase (maskelynite) are identified at the contacts between augite and labradorite wedge-shaped interfaces in the doleritic rocks of the Lockne impact structure in Sweden. The occurrence of lingunite suggests that the local pressure was above 19 GPa and the local temperature overwhelmed 1000 °C. …”
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    Lingunite-a high-pressure plagioclase polymorph at mineral interfaces in doleritic rock of the Lockne impact structure (Sweden)
  20. 1660
    “…A luciferase reporter assay demonstrated that miR-126 targets Rho associated coiled-coil containing protein kinase 1 (ROCK1) by directly binding the 3′-untranslated region. …”
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    MicroRNA-126 inhibits tumor cell invasion and metastasis by downregulating ROCK1 in renal cell carcinoma
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