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1901“…Test cells were either (a) continuously cultured in the presence of pulverized uranium-containing rock emitting 38 Bq/m(3) radon, or (b) exposed five days a week, to a 1:10,000 dilution of either tobacco or cannabis smoke from one cigarette. …”
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1902“…Knockdown of CCM3, FAM40A or FAM40B in endothelial cells by RNAi causes an increase in stress fibers and a reduction in loop formation in an in vitro angiogenesis assay, which can be reverted by inhibiting the Rho-regulated ROCK kinases. FAM40B depletion also increases endothelial permeability. …”
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1903por Yuan, Jing, Chen, Lin, Xiao, Jingshu, Qi, Xue-Kang, Zhang, Ji, Li, Xu, Wang, Zifeng, Lian, Yi-Fan, Xiang, Tong, Zhang, Yuchen, Chen, Ming-Yuan, Bei, Jin-Xin, Zeng, Yi-Xin, Feng, Lin“…SHROOM2 is a key mediator of RhoA–ROCK pathway that regulates cell motility and actin cytoskeleton organization. …”
Publicado 2019
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1904por Si, Wenwen, Ye, Shanyu, Ren, Zhenxing, Liu, Xin, Wu, Zimei, Li, Yi, Zhou, Jianhong, Zhang, Saixia, Li, Yiwei, Deng, Rudong, Chen, Dongfeng“…In addition, ROCK2 silencing markedly inhibited the effect of miR-335 on SG formation and apoptosis levels. …”
Publicado 2019
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1905por Jung, Myung-Hwa, Chico, Verónica, Ciordia, Sergio, Mena, Maria Carmen, Jung, Sung-Ju, Ortega-Villaizan, Maria Del Mar“…Rock bream iridovirus (RBIV) causes severe mass mortality in Korean rock bream (Oplegnathus fasciatus) populations. …”
Publicado 2019
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1906por Wang, Yi-Chun, Chen, Qiong, Luo, Jun-Ming, Nie, Jing, Meng, Qing-He, Shuai, Wei, Xie, Han, Xia, Jia-Mei, Wang, Hui“…The goals of this study were to investigate the role of the Notch1/PDGFRβ/ROCK1 signaling pathway in the pathogenesis of pulmonary fibrosis and to explore the possibility of treating fibrosis by targeting Notch1. …”
Publicado 2019
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1907por Stępień, Agnieszka Ewa, Gorzelany, Józef, Matłok, Natalia, Lech, Krzysztof, Figiel, Adam“…This study aimed to investigate the changes in the total polyphenolic content and antioxidant properties after subjecting Pink Rock Rose (Cistus creticus) leaves to three different drying procedures, including convection drying (CD) at 40, 50 and 60 °C; vacuum-microwave drying (VMD) at 240 W microwave power; and combined drying consisting of convective pre-drying at 50 °C followed by vacuum-microwave finish drying at 240 W microwave power (CPD-VMFD). …”
Publicado 2019
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1908por Jin, Xiang, Ye, Liping, Lin, Minhua, Gu, Binbin, Wang, Jun, He, Yequn, Li, Weilin“…Furthermore, CCHE1 overexpression led to upregulated ROCK1 in human pancreatic adenocarcinoma cell lines, whereas no significant effects of ROCK1 overexpression upon CCHE1 expression were identified. …”
Publicado 2019
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1909“…MicroRNA-466 overexpression significantly suppressed ROCK2 expression in HCC cells, whereas ROCK2 overexpression did not significantly affect microRNA-466 expression. …”
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1910“…Its actions likely include inhibition of ROCK-dependent Ca(2+) sensitisation and voltage-gated Ca(2+) channels. …”
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1911
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1912por Ji, Zheng, Meng, Qi-An, Wan, Chuan-Biao, Zhu, De-Feng, Ge, Wen-Chun, Zhang, Yan-Long, Yang, Hao, Dong, Yu, Jing, Yan“…The volcanic rocks consist of dacites, rhyolites and rhyolitic tuffs. …”
Publicado 2019
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1913por Zucchini, Cinzia, Manara, Maria Cristina, Cristalli, Camilla, Carrabotta, Marianna, Greco, Sara, Pinca, Rosa Simona, Ferrari, Cristina, Landuzzi, Lorena, Pasello, Michela, Lollini, Pier-Luigi, Gambarotti, Marco, Donati, Davide Maria, Scotlandi, Katia“…METHODS: The effects of ROCK2 depletion on metastasis were studied in NOD Scid gamma (NSG) mice injected with U-2OS cells in which ROCK2 expression had been stably silenced. …”
Publicado 2019
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1914
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1915“…A cross-sectional study was conducted to evaluate dust exposure risk at two Pt mine waste rock crusher plants (Facility A and B) in Limpopo, South Africa. …”
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1916por Porter, Lauren, Minaisah, Rose-Marie, Ahmed, Sultan, Ali, Seema, Norton, Rosemary, Zhang, Qiuping, Ferraro, Elisa, Molenaar, Chris, Holt, Mark, Cox, Susan, Fountain, Samuel, Shanahan, Catherine, Warren, Derek“…Inhibition of actomyosin activity, using the rho-associated, coiled-coil-containing protein kinase1/2 (ROCK1/2) inhibitor Y27632 or blebbistatin, reduced SUN2 mobility in the nuclear envelope and decreased the association between SUN2 and lamin A, confirming that SUN2 dynamics and interactions are influenced by actomyosin activity. …”
Publicado 2020
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1917por Hu, Jinjiao, Zhang, Hongwei, Li, Jie, Jiang, Xiuxing, Zhang, Yanhao, Wu, Qin, Shen, liwen, Shi, Jingshan, Gao, Ning“…A mechanistic study revealed that ROCK1 activation plays an important role in the arnidiol-mediated Drp1 and cofilin dephosphorylation and mitochondrial translocation, mitochondrial fission, and apoptosis. …”
Publicado 2020
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1918“…Moreover, in bladder cancer cells, EGFR-AS1 overexpression mediated the upregulation of ROCK2, while microRNA (miR)-381 mediated the downregulation of ROCK2. …”
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1919
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1920“…Furthermore, higher levels of ROCK1 and ROCK2 induced injury of endothelial cells and many inflammatory diseases of the eyes. …”
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