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Historia
24
Sal
12
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401por Manson, Megan Elizabeth, Adam, Safwaan, Steimer, Anna-Elisabeth Minder, Abdullah, Noor Rafhati Adyani, Higham, Claire Emily, Meredith, Suzanne, White, Anne, Cottrell, Elizabeth Claire, Monaghan, Phillip, Keevil, Brian George, Trainer, Peter James“…Introduction: Salivary glucocorticoids (cortisol [SalF], cortisone [SalE]) are collected non-invasively, unaffected by variation in cortisol binding globulin (CBG) and an established tool in the investigation of Cushing’s syndrome (CS). …”
Publicado 2020
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402“…In addition, SalB obviously decreased the level of Aβ. SalB elevated the protein expression of ADAM10, while downregulated BACE1 and PS1. …”
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403por Gautam, Chiteri, Srivastava, Devyani, Kociok-Köhn, Gabriele, Gosavi, Suresh W., Sharma, Vinod K., Chauhan, Ratna, Late, Dattatray J., Kumar, Abhinav, Muddassir, Mohd.“…Two Schiff base complexes of copper(ii) and cobalt(iii) having the formulae [CuL(2)] (Cu-Sal) and [CoL(3)] (Co-Sal) (HL = 2-(((2-hydroxyethyl)imino)methyl)phenol) have been synthesized and characterized microanalytically, spectroscopically and in the case of Cu-Sal using single crystal X-ray diffraction technique. …”
Publicado 2023
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404por Degen, David, Feng, Yu, Zhang, Yu, Ebright, Katherine Y, Ebright, Yon W, Gigliotti, Matthew, Vahedian-Movahed, Hanif, Mandal, Sukhendu, Talaue, Meliza, Connell, Nancy, Arnold, Eddy, Fenical, William, Ebright, Richard H“…We report that bacterial RNA polymerase (RNAP) is the functional cellular target of the depsipeptide antibiotic salinamide A (Sal), and we report that Sal inhibits RNAP through a novel binding site and mechanism. …”
Publicado 2014
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405“…Results showed that Sal alleviated MPTP-induced motor deficits in pole test. …”
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406por Chen, Kai, Guan, Yiqing, Wu, Shaoyu, Quan, Dongling, Yang, Danni, Wu, Huanxian, LV, Lin, Zhang, Guohua“…ETHNOPHARMACOLOGICAL RELEVANCE: Salvianolic acid D (Sal D) is a natural substance extracted from Radix Salviae that performs a cardiovascular benefit. …”
Publicado 2022
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407por Wang, Qin, Liu, Fangcen, Wang, Lifeng, Xie, Chen, Wu, Puyuan, Du, Shiyao, Zhou, Shujuan, Sun, Zhichen, Liu, Qin, Yu, Lixia, Liu, Baorui, Li, Rutian“…These systems can be used to reduce the side effects of Sal and improve clinical benefit. METHODS: Sal-loaded polyethylene glycol-peptide-polycaprolactone nanoparticles (Sal NPs) were fabricated under mild and non-toxic conditions. …”
Publicado 2020
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408“…Six groups were formed: Sham-Sed treated with saline (Sal) or Ros (Sham-Sed-Sal; Sham-Sed-Ros), Ovx-Sed treated with Sal or Ros (Ovx-Sed-Sal; Ovx-Sed-Ros), Ovx trained treated with Sal or Ros (Ovx-Tr-Sal; Ovx-Tr-Ros). …”
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409por Phua, Su Yin, Pornsiriwong, Wannarat, Chan, Kai Xun, Estavillo, Gonzalo M., Pogson, Barry J.“…Dexamethasone (dex)‐inducible silencing of SAL1 via hpRNAi [pOpOff:SAL1hpRNAi] yielded reduction in SAL1 transcript and protein levels, yet failed to significantly induce PAP accumulation. …”
Publicado 2018
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410“…Exosomal SphK1 promotes hepatic stellate cells (HSC) migration. Salidroside (Sal) inhibits liver fibrosis, but its mechanism is yet to be elucidated. …”
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411por Pashkunova-Martic, Irena, Kukeva, Rositsa, Stoyanova, Radostina, Pantcheva, Ivayla, Dorkov, Peter, Friske, Joachim, Hejl, Michaela, Jakupec, Michael, Hohagen, Mariam, Legin, Anton, Lubitz, Werner, Keppler, Bernhard K., Helbich, Thomas H., Ivanova, Juliana“…Moreover, Sal-H, Sal-Gd(III), and Sal-Mn(II) were able to induce perturbations in the cell cycle of treated colorectal and breast human cancer cell lines (SW480 and MCF-7, respectively). …”
Publicado 2022
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412“…SAL alone did not affect AF inducibility, but SAL therapy markedly decreased Ang II-induced AF inducibility. …”
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413por Zhuang, Pengwei, Zhang, Yanjun, Cui, Guangzhi, Bian, Yuhong, Zhang, Mixia, Zhang, Jinbao, Liu, Yang, Yang, Xinpeng, Isaiah, Adejobi Oluwaniyi, Lin, Yingxue, Jiang, Yongbo“…We further demonstrated that Sal B promoted NSPCs proliferation in dose- and time-dependent manners. …”
Publicado 2012
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414por Guo, Congcong, Li, Yun, Zhang, Rui, Zhang, Yaqin, Zhao, Junyu, Yao, Jinming, Sun, Jie, Dong, Jianjun, Liao, Lin“…Methods: Twenty-eight male Wistar rats were allocated into four groups: sham-operated, uninephrectomy (unx), diabetes with uninephrectomy (DKD) and DKD treated with SAL (DKD + SAL). SAL (70 mg/kg) was gavage administered for 8 weeks. 24-h albuminuria and serum creatinine (SCr), blood urea nitrogen (BUN), renal histological changes were examined. …”
Publicado 2018
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415por Katary, Mohamed A., Abdelsayed, Rafik, Alhashim, Abdulmohsin, Abdelhasib, Mohamed, Elmarakby, Ahmed A.“…Although Sal-B or cisplatin significantly reduced the expression of the angiogenic factor vascular endothelial growth factor (VEGF) in ESC injected mice, only Sal-B reduced expression level of COX-2 in ESC injected mice. …”
Publicado 2019
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416“…In this study, we investigated the protective effects and mechanisms of Sal on DSS-induced colitis in mice. The results demonstrated Sal was a competent candidate in the treatment of ulcerative colitis (UC). …”
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417por He, Shumei, Fan, Hongyan, Sun, Bin, Yang, Meipan, Liu, Hongxu, Yang, Jianwei, Liu, Jianxin, Luo, Sizhu, Chen, Zihan, Zhou, Jing, Xia, Lu, Zhang, Shulin, Yan, Bo“…SAL treatment alone was also demonstrated to improve the survival of infected zebrafish larvae, an effect that was amplified when combining SAL treatment with isoniazid or rifampicin. …”
Publicado 2022
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418“…We observed that SalB ameliorated SAH-induced functional deficits. …”
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419por Feng, Jiao, Niu, Peiqin, Chen, Kan, Wu, Liwei, Liu, Tong, Xu, Shizan, Li, Jingjing, Li, Sainan, Wang, Wenwen, Lu, Xiya, Yu, Qiang, Liu, Ning, Xu, Ling, Wang, Fan, Dai, Weiqi, Xia, Yujing, Fan, Xiaoming, Guo, Chuanyong“…Balb/C mice were divided into five groups: Normal control (injected with normal saline), ConA (25 mg/kg), Sal (10 mg/kg) +ConA, Sal (20 mg/kg) + ConA (Sal injected 2 h prior to ConA injection) and Sal (20 mg/kg) only. …”
Publicado 2018
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420por Yoshihara, Shigemi, Tsubaki, Toshikazu, Ikeda, Masanori, Lenney, Warren, Tomiak, Richard, Hattori, Takako, Hashimoto, Kenichi, Soutome, Toru, Kato, Shihona“…At randomization, they commenced FP/SAL or FP twice daily for 8 weeks. All were then given FP/SAL only, in a 16‐week open‐label study continuation. …”
Publicado 2019
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