“…BACKGROUND: In January 2021, the World Health Organization published the 2021–2030 roadmap for the control of neglected tropical diseases (NTDs). The goal for schistosomiasis is to achieve elimination as a public health problem (EPHP) and elimination of transmission (EOT) in 78 and 25 countries (by 2030), respectively. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, the differentially abundant miRNA cargo in host EVs associated with S. japonicum infection may also provide valuable clues for identifying novel biomarkers for schistosomiasis diagnosis.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: For seven NTDs, namely soil-transmitted helminths, schistosomiasis, lymphatic filariasis, onchocerciasis, trachoma, visceral leishmaniasis, and human African trypanosomiasis, we used mathematical transmission models to simulate the effect of programme interruptions on the dynamics of each of these diseases in different endemic settings. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…SchistoDB (http://schistoDB.net/) is a genomic database for the parasitic organism Schistosoma mansoni, one of the major causative agents of schistosomiasis worldwide. It currently incorporates sequences and annotation for S. mansoni in a single user-friendly database. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Elucidation of these metabolic mechanisms could lead to the development of new interventions for the control of schistosomiasis and other helminth diseases.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As a therapeutic, antimony has been mostly used for the treatment of leishmaniasis and schistosomiasis. The major toxic side-effects of antimonials as a result of therapy are cardiotoxicity (~9% of patients) and pancreatitis, which is seen commonly in HIV and visceral leishmaniasis co-infections. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…For example endostatin, an angiogenic inhibitor has been used to prevent promotion of metastasis in cancer and to reduce granulomas formation in schistosomiasis. An ECFR antagonist employed to restrain bronchial vessels proliferation in pseudomonas infection, has also been used for the treatment of lung cancer.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…SUMMARY: Schistosomiasis is a neglected disease with public health importance in tropical and subtropical regions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…While being prepared for a cystoscopy and more advanced imaging of the urinary tract, the family mentioned history of travel to a schistosomiasis endemic area prompting a more thorough ova and parasite examination of the urine. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Tuberculosis and schistosomiasis should be considered when treating women with gynecologic malignancies, especially those from abroad or who have spent time overseas. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, increasing evidence suggests that purinergic signaling contributes to Schistosomiasis morbidity, a neglected tropical disease caused by parasitic worms called schistosomes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In line with WHO analyses of NTDs, intestinal nematode infections, leishmaniasis, schistosomiasis, and lymphatic filariasis should be prioritised, as well as the burden of disease of cryptosporidiosis, which is largely underestimated. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Infection with Schistosoma parasitic flatworms ( Schistosoma haematobium, Schistosoma mansoni and Schistosoma japonicum ) causes the neglected tropical disease schistosomiasis. There is a need to identify new chemotherapies to treat these parasites, and G-protein coupled receptors (GPCRs) are a logical druggable targets to explore given they control key aspects of schistosome biology such as neuromuscular function and reproduction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Chromosome-level genome assemblies have recently been released for Schistosoma flatworm species that cause the disease schistosomiasis. These have allowed us to comprehensively predict schistosome LGICs, adding to prior annotations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…ABSTRACT: In many parts of the tropics, schistosomiasis is a major parasitic disease second only to malaria as a cause of morbidity and mortality. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The age-standardized DALY rates of most diseases were decreased, especially for soil-derived helminthiasis, schistosomiasis and food-borne trematodiases. The ARIMA prediction model showed that the disease burden of echinococcosis and cysticercosis exhibited an increasing trend, highlighting the need for further prevention and control. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Schistosomiasis, a potentially fatal chronic disease whose etiological agents are blood trematode worms of the genus Schistosoma spp., is one of the most prevalent and debilitating neglected diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Control and elimination of schistosomiasis is an arduous task, with current strategies proving inadequate to break transmission. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the single randomized controlled trial (RCT) identified, HIV-1 and schistosomiasis co-infected individuals receiving treatment for schistosomiasis had a significantly lower change in plasma HIV-1 RNA over three months (−0.001 log(10) copies/mL) compared to those receiving no treatment (+0.21 log(10) copies/mL), (p = 0.03). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSION: Construction of polyvalent subunit vaccine was capable to enhance immunogenicity and protection efficacy against schistosomiasis. There was correlation of the polarized Th1 response with reduction of liver egg burdens, supporting the immune deviation strategy for schistosomiasis japonica vaccine development.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso