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2741por Holtfreter, Martha Charlotte, Stachs, Oliver, Reichard, Maria, Loebermann, Micha, Guthoff, Rudolf Friedrich, Reisinger, Emil Christian“…Thus, CLSM may be a suitable non-invasive tool for the diagnosis of schistosomiasis in humans.…”
Publicado 2011
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2742“…Perturbing this binding is the key to eliminating Salmonella that complicate schistosomiasis.…”
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2743por Yang, Jianmei, Feng, Xingang, Fu, Zhiqiang, Yuan, Chunxiu, Hong, Yang, Shi, Yaojun, Zhang, Min, Liu, Jinming, Li, Hao, Lu, Ke, Lin, Jiaojiao“…The results of this study add to current understanding of the interplay between parasites and their natural hosts, and provide valuable information for the screening of vaccine candidates or new drug targets against schistosomiasis in the natural reservoir hosts in endemic areas.…”
Publicado 2012
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2744por Rigouin, Coraline, Nylin, Elyse, Cogswell, Alexis A., Schaumlöffel, Dirk, Dobritzsch, Dirk, Williams, David L.“…Because humans do not have PCS, this enzyme is of particular interest as a drug target for schistosomiasis.…”
Publicado 2013
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2745por Grenfell, Rafaella, Harn, Donald A., Tundup, Smanla, Da'dara, Akram, Siqueira, Liliane, Coelho, Paulo Marcos Zech“…BACKGROUND: Schistosomiasis mansoni is a debilitating and sometimes fatal disease. …”
Publicado 2013
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2746por Rujeni, Nadine, Nausch, Norman, Midzi, Nicholas, Cowan, Graeme J., Burchmore, Richard, Cavanagh, David R., Taylor, David W., Mduluza, Takafira, Mutapi, Francisca“…Urogenital schistosomiasis, due to Schistosoma haematobium, is endemic in sub-Saharan Africa. …”
Publicado 2013
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2747por Matoso, Leonardo Ferreira, Oliveira-Prado, Roberta, Abreu, Mery Natali Silva, Fujiwara, Ricardo Toshio, LoVerde, Philip T., Kloos, Helmut, Gazzinelli, Andréa, Correa-Oliveira, Rodrigo“…All patients positive for S. mansoni infection were treated. RESULTS: Schistosomiasis prevalence and the geometric mean of the egg count in 2001 were 59% and 61.05, respectively, decreasing to 26.8% and 8.78 in 2009. …”
Publicado 2013
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2748por dos Santos, Aldenir Feitosa, Fonseca, Saskya Araújo, César, Fernanda Andrade, de Azevedo Albuquerque, Mônica Camelo Pessoa, Santana, José Valfrido, Santana, Antônio Euzébio Goulart“…It is observed then the potential of this compound for the development of new therapies for the treatment of schistosomiasis.…”
Publicado 2014
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2749por Worku, Ligabaw, Damte, Demekech, Endris, Mengistu, Tesfa, Habtie, Aemero, Mulugeta“…Background. Intestinal schistosomiasis is one of the most widespread parasitic infections in tropical and subtropical countries. …”
Publicado 2014
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2750por Appleby, Laura J., Nausch, Norman, Erskine, Louise, Bourke, Claire D., Rujeni, Nadine, Midzi, Nicholas, Mduluza, Takafira, Mutapi, Francisca“…Further understanding the elements of a protective immune response in schistosomiasis may aid in efforts to develop a protective vaccine against this disease.…”
Publicado 2014
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2751por Mwangi, Ibrahim N., Sanchez, Melissa C., Mkoji, Gerald M., Agola, Lelo E., Runo, Steven M., Cupit, Pauline M., Cunningham, Charles“…Schistosomiasis is a neglected tropical disease caused by blood-dwelling flukes of the genus Schistosoma. …”
Publicado 2014
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2752por Greenberg, Robert M.“…Praziquantel (PZQ) is essentially the only drug currently available for treatment and control of schistosomiasis, a disease affecting hundreds of millions worldwide. …”
Publicado 2014
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2753por Beckmann, Svenja, Long, Thavy, Scheld, Christina, Geyer, Rudolf, Caffrey, Conor R., Grevelding, Christoph G.“…In the search for new drugs and drug targets to treat the flatworm disease schistosomiasis, protein kinases (PKs) have come under particular scrutiny because of their essential roles in developmental and physiological processes in schistosome parasites. …”
Publicado 2014
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2754por Neves, Bruno J., Braga, Rodolpho C., Bezerra, José C. B., Cravo, Pedro V. L., Andrade, Carolina H.“…Morbidity and mortality caused by schistosomiasis are serious public health problems in developing countries. …”
Publicado 2015
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2755por Nausch, Norman, Appleby, Laura J., Sparks, Alexandra M., Midzi, Nicholas, Mduluza, Takafira, Mutapi, Francisca“…CONCLUSION: This study demonstrates that ILC2s are diminished in young helminth infected children and restored by removal of the parasites by treatment, indicating a previously undescribed association between a human parasitic infection and ILC2s and suggesting a role of ILC2s before the establishment of protective acquired immunity in human schistosomiasis.…”
Publicado 2015
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2756por Habib, Mohamed R., Mohamed, Azza H., Osman, Gamalat Y., Sharaf El-Din, Ahmed T., Mossalem, Hanan S., Delgado, Nadia, Torres, Grace, Rolón-Martínez, Solymar, Miller, Mark W., Croll, Roger P.“…In addition to providing novel subjects for comparative studies of histaminegic neurons in gastropods, Biomphalaria is also the major intermediate host for the digenetic trematode parasite, which causes human schistosomiasis. The study therefore provides a foundation for understanding potential roles for histamine in interactions between the snail hosts and their trematode parasites.…”
Publicado 2015
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2757“…BACKGROUND: As plans to expand mass drug treatment campaigns to fight schistosomiasis form, worries about reliance on praziquantel as the sole available treatment motivate the investigation for novel antischistosomal compounds. …”
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2758“…INTRODUCTION: Amebiasis is the third leading cause of death after malaria and schistosomiasis. Diagnosis is based on microscopy, culture, isoenzyme analysis, and serology-based techniques. …”
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2759por MENDONÇA, Adriana Maria B., FEITOSA, Ana Paula S., VERAS, Dyana L., MATOS-ROCHA, Thiago J., CAVALCANTI, Marília G. dos Santos, BARBOSA, Constança Clara G. S., BRAYNER, Fábio A., ALVES, Luiz C.“…INTRODUCTION: Schistosomiasis is a chronic disease caused by trematode flatworms of the genus Schistosoma and its control is dependent on a single drug, praziquantel (PZQ), but concerns over PZQ resistance have renewed interest in evaluating the in vitro susceptibility of recent isolates of Schistosoma mansoni to PZQ in comparison with well-established strains in the laboratory. …”
Publicado 2016
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2760“…In schistosomiasis, egg-induced hepatic granuloma formation is a cytokine-mediated, predominantly CD4(+) Th2 immune response that can give rise to hepatic fibrosis. …”
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