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2841“…Schistosoma japonicum is an infectious blood-dwelling trematode with a complex lifecycle that causes the tropical disease schistosomiasis. In this study, we analyzed the transcriptome of Schistosoma japonicum to discover alternative splicing events in this parasite, by applying RNA-seq to cDNA library of adults and schistosomula. …”
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2842por Figueiredo, Barbara C., Da'dara, Akram A., Oliveira, Sergio C., Skelly, Patrick J.“…Schistosoma mansoni is a blood fluke parasite that causes schistosomiasis, a debilitating disease of global public health importance. …”
Publicado 2015
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2843por Kittur, Nupur, Castleman, Jennifer D., Campbell, Carl H., King, Charles H., Colley, Daniel G.“…More studies directly comparing the two assays in low-prevalence areas are essential to inform decision-making by national schistosomiasis control programs.…”
Publicado 2016
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2844“…Predisposing factors include bladder exstrophy, schistosomiasis, and other causes of chronic bladder irritation. …”
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2845por Cai, Pengfei, Liu, Shuai, Piao, Xianyu, Hou, Nan, Gobert, Geoffrey N., McManus, Donald P., Chen, Qijun“…Schistosomiasis is a chronic and debilitating disease caused by blood flukes (digenetic trematodes) of the genus Schistosoma. …”
Publicado 2016
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2846por Zhu, Lihui, Liu, Juntao, Dao, Jinwei, Lu, Ke, Li, Hao, Gu, Huiming, Liu, Jinming, Feng, Xingang, Cheng, Guofeng“…Overall, our findings demonstrate that S. japonicum EVs could be implicated in the pathogenesis of schistosomiasis via a mechanism involving the transfer of their cargo miRNAs to hosts. …”
Publicado 2016
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2847por Lu, Zhigang, Sessler, Florian, Holroyd, Nancy, Hahnel, Steffen, Quack, Thomas, Berriman, Matthew, Grevelding, Christoph G.“…One representative example is the trematode Schistosoma, which causes schistosomiasis, an infectious disease, whose pathology is associated with egg production. …”
Publicado 2016
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2848por Wangchuk, Phurpa, Giacomin, Paul R., Pearson, Mark S., Smout, Michael J., Loukas, Alex“…Schistosomiasis and trichuriasis are two of the most common neglected tropical diseases (NTD) that affect almost a billion people worldwide. …”
Publicado 2016
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2849por Wang, Xing-Quan, Wang, Feng-Peng, Chen, Wei, Huang, Jun, Bazaka, Kateryna, Ostrikov, Kostya (Ken)“…Schistosoma japonicum is a widespread human and animal parasite that causes intestinal and hepatosplenic schistosomiasis linked to colon, liver and bladder cancers, and anemia. …”
Publicado 2016
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2850“…In an attempt to reduce this burden, the Department of Health of the province of KwaZulu-Natal (KZN) established in 1998 a programme for helminth control that aimed at regularly treating primary school children for schistosomiasis and intestinal helminths. This article describes the baseline situation and the effect of treatment on geohelminth infection in a rural part of the province. …”
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2851“…Fibrosis generally results from chronic hepatic injury caused by various factors, mainly viral infection, schistosomiasis, and alcoholism; however, the exact pathological mechanisms are still unknown. …”
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2852por Wang, Weisi, Li, Qiang, Wei, Yufen, Xue, Jian, Sun, Xiao, Yu, Yang, Chen, Zhuo, Li, Shizhu, Duan, Liping“…Malaria and schistosomiasis are two of the most socioeconomically devastating parasitic diseases in tropical and subtropical countries. …”
Publicado 2017
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2853por Wang, Qi, Chou, Xin, Guan, Fei, Fang, Zhengming, Lu, Shengjun, Lei, Jiahui, Li, Yonglong, Liu, Wenqi“…Our findings identify a novel pro-fibrogenic role of hepatocytes in schistosomiasis-induced liver fibrosis that is dependent on Wnt signalling, which may serve as a potential target for ameliorating hepatic fibrosis caused by helminths.…”
Publicado 2017
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2854por Matos-Rocha, Thiago José, de Lima, Maria do Carmo Alves, da Silva, Anekécia Lauro, de Oliveira, Jamerson Ferreira, Gouveia, Allana Lemos Andrade, da Silva, Vinícius Barros Ribeiro, de Almeida, Antônio Sérgio Alves, Brayner, Fábio André, Cardoso, Pablo Ramon Gualberto, Pitta-Galdino, Marina da Rocha, Pitta, Ivan da Rocha, Rêgo, Moacyr Jesus Barreto de Melo, Alves, Luiz Carlos, Pitta, Maira Galdino da Rocha“…INTRODUCTION: Schistosomiasis is an infectious parasitic disease caused by trematodes of the genus Schistosoma, which threatens at least 258 million people worldwide and its control is dependent on a single drug, praziquantel. …”
Publicado 2017
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2855“…Another example is injections of praziquantel for treatment and cure of schistosomiasis in Central and Northern Africa, with a focus in Egypt that has spread hepatitis C virus. …”
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2856“…OBJECTIVE: To investigate the incidence of insulin resistance (IR) and diabetes in patients with chronic hepatic schistosomiasis japonica (HSJ) and portosystemic shunts (PSS). …”
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2857por Munisi, David Z., Buza, Joram, Mpolya, Emmanuel A., Angelo, Teckla, Kinung'hi, Safari M.“…Administering more than one treatment may increase Praziquantel cure and egg reduction rates, thereby hastening achievement of schistosomiasis transmission control. A total of 431 S. mansoni-infected schoolchildren were randomized to receive either a single or repeated 40 mg/kg Praziquantel dose. …”
Publicado 2017
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2858por Abe, Eniola Michael, Guan, Wei, Guo, Yun-Hai, Kassegne, Kokouvi, Qin, Zhi-Qiang, Xu, Jing, Chen, Jun-Hu, Ekpo, Uwem Friday, Li, Shi-Zhu, Zhou, Xiao-Nong“…Also, we identify the gaps and areas where there is need for urgent intervention to facilitate effective integrated control of schistosomiasis and other snail-borne trematode infections. …”
Publicado 2018
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2859por Vasconcelos, Elton J R, Mesel, Vinícius C, daSilva, Lucas F, Pires, David S, Lavezzo, Guilherme M, Pereira, Adriana S A, Amaral, Murilo S, Verjovski-Almeida, Sergio“…Little is known about the functionality of lncRNAs in evolutionarily ancient non-model metazoan organisms, like Schistosoma mansoni, the parasite that causes schistosomiasis, one of the most prevalent infectious-parasitic diseases worldwide. …”
Publicado 2018
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2860por You, Hong, Harvie, Marina, Du, Xiaofeng, Rivera, Vanessa, Zhang, Ping, McManus, Donald P.“…There is a pressing need to develop vaccines for schistosomiasis given the current heavy dependency on praziquantel as the only available drug for treatment. …”
Publicado 2018
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