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2961por Pinto-Almeida, António, Mendes, Tiago, Armada, Ana, Belo, Silvana, Carrilho, Emanuel, Viveiros, Miguel, Afonso, Ana“…BACKGROUND: Schistosomiasis is a neglected disease caused by a trematode of the genus Schistosoma that is second only to malaria in public health significance in Africa, South America, and Asia. …”
Publicado 2015
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2962“…Schistosomiasis, caused by parasitic flatworms of the genus Schistosoma, is a neglected tropical disease affecting hundreds of millions globally. …”
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2963por Everts, Bart, Tussiwand, Roxane, Dreesen, Leentje, Fairfax, Keke C., Huang, Stanley Ching-Cheng, Smith, Amber M., O’Neill, Christina M., Lam, Wing Y., Edelson, Brian T., Urban, Joseph F., Murphy, Kenneth M., Pearce, Edward J.“…However, liver fibrosis, an IL-13–mediated pathological consequence of wound healing in chronic schistosomiasis, was exacerbated in Batf3(−/−) mice infected with Schistosoma mansoni. …”
Publicado 2016
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2964por Bhaumik, Soumyadeep, Karimkhani, Chante, Czaja, Christopher A., Williams, Hywel C., Rani, Monica, Nasser, Mona, Boyers, Lindsay N., Dmitruk, Sergei, Dellavalle, Robert P.“…Yellow fever, echinococcus, onchocerciasis, and schistosomiasis representation was well-aligned with DALY. …”
Publicado 2015
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2965por Cavaca, Aline Guio, Emerich, Tatiana Breder, Vasconcellos-Silva, Paulo Roberto, dos Santos-Neto, Edson Theodoro, Oliveira, Adauto Emmerich“…PRINCIPAL FINDINGS: Quantitatively, the DNMs identified diseases associated with poverty, including tuberculosis, leprosy, schistosomiasis, leishmaniasis, and trachoma. Apart from these, diseases with outbreaks in the period evaluated, including whooping cough and meningitis, some cancers, respiratory diseases, ischaemic heart disease, and stroke, were also seldom addressed by the media. …”
Publicado 2016
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2966“…BACKGROUND: Schistosomiasis is an important helminth infection of humans. …”
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2967“…Although this immunotolerogenic environment is favorable in the setting of organ transplantation, it is detrimental in chronic infectious liver diseases like hepatitis B or C, malaria, schistosomiasis or tumorigenesis, leading to pathogen persistence and weak anti-tumor effects. …”
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2968por Barda, Beatrice, Coulibaly, Jean T., Puchkov, Maxim, Huwyler, Jörg, Hattendorf, Jan, Keiser, Jennifer“…BACKGROUND: Schistosomiasis affects millions of people, yet treatment options are limited. …”
Publicado 2016
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2969“…BACKGROUND: Schistosoma species are responsible for the disease schistosomiasis, a highly prevalent helminthic disease that requires a freshwater snail as intermediate host. …”
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2970por Kandeel, Amr, Genedy, Mohamad, El‐Refai, Samir, Funk, Anna L., Fontanet, Arnaud, Talaat, Maha“…An estimated 29% reduction in HCV RNA prevalence has been seen since 2008, which is largely attributable to the ageing of the group infected 40–50 years ago during the mass schistosomiasis treatment campaigns. Prevention efforts may have also contributed to this decline, with an estimated 75% (95% CI 6–45) decrease in HCV incidence in the 0–19 year age groups over the past 20 years. …”
Publicado 2016
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2971por Chua, Ming Jang, Arnold, Megan S.J., Xu, Weijun, Lancelot, Julien, Lamotte, Suzanne, Späth, Gerald F., Prina, Eric, Pierce, Raymond J., Fairlie, David P., Skinner-Adams, Tina S., Andrews, Katherine T.“…Malaria, schistosomiasis and leishmaniases are among the most prevalent tropical parasitic diseases and each requires new innovative treatments. …”
Publicado 2016
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2972por Saathoff, Elmar, Olsen, Annette, Magnussen, Pascal, Kvalsvig, Jane D, Becker, Wilhelm, Appleton, Chris C“…BACKGROUND: Schistosomiasis is one of the major health problems in tropical and sub-tropical countries, with school age children usually being the most affected group. …”
Publicado 2004
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2973por Tekwu, Emmanuel Mouafo, Bosompem, Kwabena Mante, Anyan, William Kofi, Appiah-Opong, Regina, Owusu, Kofi Baffour-Awuah, Tettey, Mabel Deladem, Kissi, Felicia Amanfo, Appiah, Alfred Ampomah, Penlap Beng, Veronique, Nyarko, Alexander Kwadwo“…Schistosomiasis is a Neglected Tropical Diseases which can be prevented with mass deworming chemotherapy. …”
Publicado 2017
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2974“…BACKGROUND: Praziquantel has been cited as the only drug for treating schistosomiasis. However, concerns over drug resistance have encouraged the search for novel drug leads. …”
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2975por Wright, Brandon J., Bickham-Wright, Utibe, Yoshino, Timothy P., Jackson, Meyer B.“…The human blood fluke Schistosoma mansoni causes intestinal schistosomiasis, a widespread neglected tropical disease. …”
Publicado 2017
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2976por Cevallos, William, Calvopiña, Manuel, Nipáz, Victoria, Vicente-Santiago, Belén, López-Albán, Julio, Fernández-Soto, Pedro, Guevara, Ángel, Muro, Antonio“…Some cross reactivity was detected against Paragonimus mexicanus, Fasciola hepatica, Schistosomiasis, Taenia solium, Strongyloides stercoralis, Mansonella spp., and Vampirolepis nana. …”
Publicado 2017
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2977por Xu, Tianhua, Chen, Jinling, Zhu, Dandan, Chen, Liuting, Wang, Jianxin, Sun, Xiaolei, Hu, Bin, Duan, Yinong“…Schistosomiasis is characterized by egg deposition, granulomatous inflammatory reaction and then subsequent hepatic fibrosis formation. …”
Publicado 2017
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2978por Koslowski, Nicole, Sombetzki, Martina, Loebermann, Micha, Engelmann, Robby, Grabow, Niels, Österreicher, Christoph H., Trauner, Michael, Mueller-Hilke, Brigitte, Reisinger, Emil C.“…The best long-term strategy to control schistosomiasis may be to develop an immunization. Therefore, we designed a two-step Schistosoma mansoni infection model to study the immune-stimulating effect of a primary infection with either male or female cercariae, measured on the basis of TH1/TH2-response, granuloma size and hepatic fibrosis after a secondary bisexual S. mansoni challenge. …”
Publicado 2017
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2979por Kumar, Rahul, Mickael, Claudia, Kassa, Biruk, Gebreab, Liya, Robinson, Jeffrey C., Koyanagi, Daniel E., Sanders, Linda, Barthel, Lea, Meadows, Christina, Fox, Daniel, Irwin, David, Li, Min, McKeon, B. Alexandre, Riddle, Suzette, Dale Brown, R., Morgan, Leslie E., Evans, Christopher M., Hernandez-Saavedra, Daniel, Bandeira, Angela, Maloney, James P., Bull, Todd M., Janssen, William J., Stenmark, Kurt R., Tuder, Rubin M., Graham, Brian B.“…Pulmonary arterial hypertension (PAH) is an obstructive disease of the precapillary pulmonary arteries. Schistosomiasis-associated PAH shares altered vascular TGF-β signalling with idiopathic, heritable and autoimmune-associated etiologies; moreover, TGF-β blockade can prevent experimental pulmonary hypertension (PH) in pre-clinical models. …”
Publicado 2017
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2980por Elom, Juliana Eze, Odikamnoro, Oliver O., Nnachi, Agwu Ulu, Ikeh, Ifeanyi, Nkwuda, John O.“…BACKGROUND: Schistosomiasis, a chronic, debilitating and neglected tropical and sub-tropical water-borne ailment, is highly endemic in Nigeria, especially among primary school children in rural communities. …”
Publicado 2017
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