“…Climate change may alter the geographical distribution of schistosomiasis by affecting the suitability of freshwater bodies for hosting parasite and snail populations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The freshwater snail Oncomelania hupensis is the only intermediate host of Schistosoma japonicum, which causes schistosomiasis. This disease is endemic in the Far East, especially in mainland China. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Schistosomiasis is a common debilitating human parasitic disease in (sub)tropical areas, however, schistosome infections can also protect against a variety of inflammatory diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The skin provides an important first line of defence and immunological barrier to invasive pathogens, but immune responses must also be regulated to maintain barrier function and ensure tolerance of skin surface commensal organisms. In schistosomiasis-endemic regions, populations can experience repeated percutaneous exposure to schistosome larvae, however little is known about how repeated exposure to pathogens affects immune regulation in the skin. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The reproductive development and maturation of female schistosomes are crucial since their released eggs are responsible for the host immunopathology and transmission of schistosomiasis. However, little is known about the nutrients required by female Schistosoma japonicum during its sexual maturation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The pathophysiology of female genital schistosomiasis (FGS) is only partially understood. This study aims to describe the histopathological findings, polymerase chain reaction (PCR) results, and gynecological manifestations of FGS in women with different intensities of Schistosoma haematobium infection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Schistosomiasis is a major public health problem in Kenya as well as in many other tropical countries and is considered one of the most prevalent diseases in the rural population. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: About 49% of cases and 52% of controls had S. mansoni infection prior to HIV seroconversion (or at the time of a similar study visit, for controls): odds ratio, adjusting for ethnicity, religion, marital status, education, occupation, frequency of alcohol consumption in previous 3 months, number of sexual partners while drunk, duration of stay in the community, and history of schistosomiasis treatment in the past 2 years was 1.23 (95% CI 0.3–5.7) P = 0.79. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Schistosomiasis japonica remains a major public health problem in China. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Further work defining the role of these schistosomula EVs and the function/stability of intra- and extra-vesicular sncRNA components presents tremendous opportunities for developing novel schistosomiasis diagnostics or interventions.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In view of the call by the World Health Organization (WHO) for elimination of schistosomiasis as a public health problem by 2025, use of molluscicides in snail control to supplement chemotherapy–based control efforts is likely to increase in the coming years. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We identified epitopic-like regions in 206 parasite proteins and present the first example of a plant protein (BetV1) that is the commonest allergen in pollen in a worm, and confirming it as the target of IgE in schistosomiasis infected humans. The identification of significant similarity, inclusive of the epitopic regions, between allergens and helminth proteins against which IgE is an observed marker of protective immunity explains the ‘off-target’ effects of the IgE-mediated immune system in allergy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The purpose of this study was to characterize Schistosoma japonicum vesicle-associated membrane protein 2 (SjVAMP2) and to investigate its potential as a candidate vaccine against schistosomiasis. METHODOLOGY/PRINCIPAL FINDINGS: The sequence of SjVAMP2 was analyzed, cloned, expressed and characterized. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Schistosomiasis is a kind of parasitic zoonoses which causes serious damage to public health and social development. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Chagas disease was the most common cause of death (58 928 deaths; 76.7%), followed by schistosomiasis (6319 deaths; 8.2%) and leishmaniasis (3466 deaths; 4.5%). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Schistosomiasis is one of the most common human parasitic diseases whose socioeconomic impact is only surpassed by malaria. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We studied the extent to which the disease burden from nine NTDs (lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths, trachoma, Chagas disease, human African trypanosomiasis, leprosy, visceral leishmaniasis) was concentrated in the poorest countries in 1990 and 2010, and how this would change by 2020 in case the WHO targets are met. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Schistosomiasis is a tropical parasitic disease afflicting ~200 million people worldwide and current therapy depends on a single drug (praziquantel) which exhibits several non-optimal features. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These findings gave the reasonable reasons for World Health Organization to produce (R)-PZQ as a replacement for rac-PZQ for the treatment of schistosomiasis.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Schistosoma mansoni, one of the causative agents of human schistosomiasis, has a unique antioxidant network that is key to parasite survival and a valuable chemotherapeutic target. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso