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3181por Viana, Mafalda, Faust, Christina L., Haydon, Daniel T., Webster, Joanne P., Lamberton, Poppy H. L.“…Drug resistance traits are often associated with life‐history costs in the absence of treatment. Schistosomiasis control programmes rely on mass drug administration to reduce human morbidity and mortality. …”
Publicado 2017
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3182por Zhang, Si-Ming, Bu, Lijing, Laidemitt, Martina R., Lu, Lijun, Mutuku, Martin W., Mkoji, Gerald M., Loker, Eric S.“…Biomphalaria snails are obligate vectors of the blood fluke Schistosoma mansoni, a major etiologic agent of human intestinal schistosomiasis. Our data show that mitogenomes from African and Neotropical Biomphalaria are highly conserved. …”
Publicado 2018
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3183por Wang, Weisi, Mao, Qiang, Yao, Junmin, Yang, Weijia, Zhang, Qiming, Lu, Wencheng, Deng, Zhuohui, Duan, Liping“…Using molluscicides to control snail populations is an important strategy to interrupt schistosomiasis transmission and to prevent the spread of the invasive species. …”
Publicado 2018
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3184“…BACKGROUND: The development of new treatments against schistosomiasis is imperative but lacks commercial interest. …”
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3185por Bais, Swarna, Berry, Corbett T., Liu, Xiaohong, Ruthel, Gordon, Freedman, Bruce D., Greenberg, Robert M.“…Parasitic flatworms of the genus Schistosoma cause schistosomiasis, a neglected tropical disease estimated to affect over 200 million people worldwide. …”
Publicado 2018
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3186por Roquis, David, Taudt, Aaron, Geyer, Kathrin K., Padalino, Gilda, Hoffmann, Karl F., Holroyd, Nancy, Berriman, Matt, Aliaga, Benoît, Chaparro, Cristian, Grunau, Christoph, Augusto, Ronaldo de Carvalho“…Hence, components of the histone methylation (and demethylation) machinery may provide suitable Schistosomiasis control targets.…”
Publicado 2018
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3187por Yang, Ya, Cheng, Wanting, Wu, Xiaoying, Huang, Shaoyu, Deng, Zhuohui, Zeng, Xin, Yuan, Dongjuan, Yang, Yu, Wu, Zhongdao, Chen, Yue, Zhou, Yibiao, Jiang, Qingwu“…BACKGROUND: Schistosomiasis is a snail-borne parasitic disease and is endemic in many tropical and subtropical countries. …”
Publicado 2018
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3188por Woode, Maame Esi, Khan, Jahangir A. M., Thomson, Rachael, Niessen, Louis Wilhelmus“…The COUNTDOWN multicountry studies focus on scaled-up implementation of integrated control strategies against four diseases: lymphatic filariasis, onchocerciasis, schistosomiasis and soil-transmitted helminthiasis. The objective of the COUNTDOWN economic study is to assess the multicountry implementation of control interventions in terms of equity, impact and efficiency. …”
Publicado 2018
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3189por Amara, Rokaya O, Ramadan, Alyaa A, El-Moslemany, Riham M, Eissa, Maha M, El-Azzouni, Mervat Z, El-Khordagui, Labiba K“…In this study, the effect of LNCs on the PD activity and pharmacokinetics of praziquantel (PZQ), the mainstay of schistosomiasis chemotherapy, was investigated. MATERIALS AND METHODS: The composition of LNCs was modified to increase PZQ payload and to enhance membrane permeability. …”
Publicado 2018
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3190por Alhusaini, Ahlam, Fadda, Laila, Hassan, Iman, Ali, Hanaa M., Alsaadan, Njood, Aldowsari, Nouf, Aldosari, Azizah, Alharbi, Bshayer“…BACKGROUND: Copper is an essential element that is used widely in agriculture as fungicides and insecticides; for example, it is used to control schistosomiasis and as an antiseptic and germicide. Copper sulfate (CuSO(4)) induces multiorgan dysfunction through the stimulation of reactive oxygen species and oxidative stress. …”
Publicado 2018
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3191por van Grootveld, Rebecca, van Dam, Govert J., de Dood, Claudia, de Vries, Jutte J. C., Visser, Leo G., Corstjens, Paul L. A. M., van Lieshout, Lisette“…Schistosomiasis is a parasitic disease affecting over 250 million people in the tropics. …”
Publicado 2018
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3192“…BACKGROUND: Schistosomiasis is one of the most harmful parasitic diseases worldwide, praziquantel being the only drug in widespread use to treat it. …”
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3193por Alves, Clarice Carvalho, Araujo, Neusa, Bernardes, Wilma Patrícia de Oliveira Santos, Mendes, Mariana Moreira, Oliveira, Sergio Costa, Fonseca, Cristina Toscano“…The helminth Schistosoma mansoni is one of main causes of human schistosomiasis, a health and economic concern in some of the world's poorest countries. …”
Publicado 2018
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3194por El-Khadragy, Manal F., Al-Olayan, Ebtesam M., Elmallah, Mohammed I. Y., Alharbi, Afra M., Yehia, Hany M., Abdel Moneim, Ahmed E.“…BACKGROUND: Considerable morbidity, mortality, and economic loss result from schistosomiasis infection. Deposition of Schistosoma eggs in the hepatic portal vein is considered as the main causative agent for the development of liver fibrosis and subsequent liver cirrhosis. …”
Publicado 2019
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3195por Araujo Navas, Andrea L., Osei, Frank, Leonardo, Lydia R., Soares Magalhães, Ricardo J., Stein, Alfred“…Uncertainties in spatial modeling studies of schistosomiasis (SCH) are relevant for the reliable identification of at-risk populations. …”
Publicado 2019
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3196por Frahm, Sören, Anisuzzaman, Anisuzzaman, Prodjinotho, Ulrich Fabien, Vejzagić, Nermina, Verschoor, Admar, Prazeres da Costa, Clarissa“…BACKGROUND: The arsenal in anthelminthic treatment against schistosomiasis is limited and relies almost exclusively on a single drug, praziquantel (PZQ). …”
Publicado 2019
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3197por Ribeiro, Alane Andrelino, Lupatini, Evandro de Oliveira, dos Santos, Diana Graziele“…Drugs were donated for the treatment of HIV/Aids, malaria, leishmaniasis, diabetes, cholera, schistosomiasis, tuberculosis, influenza, opportunistic diseases, immunizations, nutrition support, and health conditions associated with natural disasters. …”
Publicado 2018
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3198por Haggag, Ayat A., Rabiee, Amal, Abd Elaziz, Khaled M., Campbell, Carl H., Colley, Daniel G., Ramzy, Reda M. R.“…We conclude that in areas with extremely low prevalence S. mansoni egg–negative and CCA-Trace or 1+ children are unlikely to pose substantial risks to continued transmission of schistosomiasis. In this setting, POC-CCA Trace or 1+ readings are likely to be false positives or perhaps represent low-level single-sex schistosome infections.…”
Publicado 2019
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3199por Portet, Anaïs, Pinaud, Silvain, Chaparro, Cristian, Galinier, Richard, Dheilly, Nolwenn M., Portela, Julien, Charriere, Guillaume M., Allienne, Jean-François, Duval, David, Gourbal, Benjamin“…Understanding the mechanisms allowing parasites to adapt rapidly and efficiently to new hosts is critical to control disease emergence and risks of Schistosomiasis outbreaks.…”
Publicado 2019
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3200por Egesa, Moses, Lubyayi, Lawrence, Tukahebwa, Edridah M., Bagaya, Bernard S., Chalmers, Iain W., Wilson, Shona, Hokke, Cornelis H., Hoffmann, Karl F., Dunne, David W., Yazdanbakhsh, Maria, Labuda, Lucja A., Cose, Stephen“…Testing more schistosomula antigens using this approach could provide immune‐epidemiology identifiers necessary for prioritizing next generation schistosomiasis vaccine candidates.…”
Publicado 2018
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