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3201por Egesa, Moses, Lubyayi, Lawrence, Jones, Frances M., van Diepen, Angela, Chalmers, Iain W., Tukahebwa, Edridah M., Bagaya, Bernard S., Hokke, Cornelis H., Hoffmann, Karl F., Dunne, David W., Elliott, Alison M., Yazdanbakhsh, Maria, Wilson, Shona, Cose, Stephen“…Schistosoma mansoni‐infected individuals were recruited from a schistosomiasis endemic area in Uganda (n = 372), treated with 40 mg/kg praziquantel (PZQ) and followed up at five weeks and at one year post‐treatment. …”
Publicado 2018
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3202por Haggag, Ayat A., Casacuberta Partal, Miriam, Rabiee, Amal, Abd Elaziz, Khaled M., Campbell, Carl H., Colley, Daniel G., Ramzy, Reda M. R.“…We conclude that CCA trace and 1+ readings, in Kato–Katz S. mansoni egg-negative children in this area with very low levels of intestinal schistosomiasis, are not consistently altered or rendered consistently negative following repeated PZQ treatments and are therefore likely to represent false-positive readings. …”
Publicado 2019
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3203por Panic, Gordana, Barda, Beatrice, Kovač, Jana, Coulibaly, Jean T., Keiser, Jennifer“…BACKGROUND: Urinary schistosomiasis, caused by Schistosoma haematobium, remains a significant public health problem worldwide, despite years of efforts to control it. …”
Publicado 2019
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3204por Mutuku, Martin W., Laidemitt, Martina R., Beechler, Brianna R., Mwangi, Ibrahim N., Otiato, Fredrick O., Agola, Eric L., Ochanda, Horace, Kamel, Bishoy, Mkoji, Gerald M., Steinauer, Michelle L., Loker, Eric S.“…This argues for an integrated, basin-wide plan for schistosomiasis control to counteract rapid reinfections facilitated by large snail populations and movements of infected people around the lake.…”
Publicado 2019
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3205por Wharton-Smith, Alexandra, Rassi, Christian, Batisso, Esey, Ortu, Giuseppina, King, Rebecca, Endriyas, Misganu, Counihan, Helen, Hamade, Prudence, Getachew, Dawit“…This study, part of broader implementation research in Ethiopia, applied a gender lens to health seeking for five NTDs: lymphatic filariasis, podoconiosis, schistosomiasis, soil-transmitted helminth infection and trachoma. …”
Publicado 2019
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3206por Buddenborg, Sarah K., Kamel, Bishoy, Bu, Lijing, Zhang, Si-Ming, Mkoji, Gerald M., Loker, Eric S.“…BACKGROUND: Schistosomiasis is one of the world’s most common NTDs. …”
Publicado 2019
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3207por Brunner, Julia S., Vulliard, Loan, Hofmann, Melanie, Kieler, Markus, Lercher, Alexander, Vogel, Andrea, Russier, Marion, Brüggenthies, Johanna B., Kerndl, Martina, Saferding, Victoria, Niederreiter, Birgit, Junza, Alexandra, Frauenstein, Annika, Scholtysek, Carina, Mikami, Yohei, Klavins, Kristaps, Krönke, Gerhard, Bergthaler, Andreas, O’Shea, John J., Weichhart, Thomas, Meissner, Felix, Smolen, Josef S., Cheng, Paul, Yanes, Oscar, Menche, Jörg, Murray, Peter J., Sharif, Omar, Blüml, Stephan, Schabbauer, Gernot“…Multinucleated giant cells (MGCs) are implicated in many diseases including schistosomiasis, sarcoidosis and arthritis. MGC generation is energy intensive to enforce membrane fusion and cytoplasmic expansion. …”
Publicado 2020
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3208por Kamdem, Severin Donald, Kuemkon, Erve Martial, Kamguia, Leonel Meyo, Tchanana, Gladys K., Konhawa, Francis, Nche, Frungwa, Oumarou, Alim, Hamza, Mamadou, Essomba, René Ghislain, Kengne, Michel, Ondigui, Bienvenu Etogo, Assoumou, Marie Claire Okomo, Brombacher, Frank, Nono, Justin Komguep“…A cross-sectional study was conducted in a S. mansoni endemic area in rural Cameroon. 1002 Participants were screened and 234 of them, free from all common liver-affecting diseases in the area (schistosomiasis, malaria, hepatitis B and C) and with no ultrasonographic signs of liver disease were selected and their liver parameters measured by ultrasonography. …”
Publicado 2020
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3209por Guler, Reto, Mpotje, Thabo, Ozturk, Mumin, Nono, Justin K., Parihar, Suraj P., Chia, Julius Ebua, Abdel Aziz, Nada, Hlaka, Lerato, Kumar, Santosh, Roy, Sugata, Penn-Nicholson, Adam, Hanekom, Willem A., Zak, Daniel E., Scriba, Thomas J., Suzuki, Harukazu, Brombacher, Frank“…In striking contrast, Type 2-controlled schistosomiasis exacerbates during infected Batf2(−/−) mice with increased intestinal fibro-granulomatous inflammation, pro-fibrotic immune cells, and elevated cytokine production leading to wasting disease and early death. …”
Publicado 2018
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3210por Mota, Ester Alves, do Patrocínio, Andressa Barban, Rodrigues, Vanderlei, da Silva, João Santana, Pereira, Vanessa Carregaro, Guerra-Sá, Renata“…Changes to the immunological background thus induce epigenetic changes in hepatic tissues and alterations in S. mansoni gene expression, which attenuate liver symptoms in the acute phase of schistosomiasis.…”
Publicado 2020
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3211“…On the other hand, complications common to both diabetes and some tropical infections might provide an opportunity for shared services—for example, for eye health (trachoma and onchocerciasis), ulcer care (leprosy), or renal support (schistosomiasis). More research about the interaction of diabetes and infections in tropical countries is needed, and the infectious disease burden in these countries is another reason to step up global efforts to improve prevention and care for diabetes.…”
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3212por Boutayeb, A.“…Low-income countries are particularly affected by lymphatic filariasis, leishmaniasis, schistosomiasis, Buruli ulcer, cholera, cysticercosis, dracunculiasis, foodborne trematode infections, hydatidosis, soil-transmitted helminthiasis (ascariasis, trichuriasis, hookworm diseases), trachoma, sleeping sickness, onchocerciasis, Chagas disease, dengue and others. …”
Publicado 2010
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3213“…Coagulation test and platelet count should be used to monitor and manage schistosomiasis-related complications.…”
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3214por Souza, Cláudia, Sanches, Rodrigo C. O., Assis, Natan R. G., Marinho, Fábio V., Mambelli, Fábio S., Morais, Suellen B., Gimenez, Enrico G. T., Guimarães, Erika S., Castro, Tiago B. R., Oliveira, Sergio C.“…Schistosomiasis is a human parasitic disease responsible for serious consequences for public health, as well as severe socioeconomic impacts in developing countries. …”
Publicado 2020
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3215por Nono, Justin Komguep, Fu, Kai, Mpotje, Thabo, Varrone, Georgianna, Aziz, Nada Abdel, Mosala, Paballo, Hlaka, Lerato, Kamdem, Severin Donald, Xu, Daigen, Spangenberg, Thomas, Brombacher, Frank“…We applied the mouse CCl(4)-driven liver fibrosis model, the mouse chronic schistosomiasis liver fibrosis model, as well as novel 2D and 3D human cell-based co-culture of human hepatocytes, KCs (Kupffer cells), LECs (Liver Endothelial Cells), HSCs (Hepatic Stellate Cells) and/or myofibroblasts to mimic in vivo fibrotic responses and dynamics. …”
Publicado 2020
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3216por Queiroz, Fábio Ribeiro, Portilho, Laysa Gomes, Jeremias, Wander de Jesus, Babá, Élio Hideo, do Amaral, Laurence Rodrigues, Silva, Luciana Maria, Coelho, Paulo Marcos Zech, Caldeira, Roberta Lima, Gomes, Matheus de Souza“…BACKGROUND: Biomphalaria glabrata snails are widely distributed in schistosomiasis endemic areas like America and Caribe, displaying high susceptibility to infection by Schistosoma mansoni. …”
Publicado 2020
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3217por Kapungu, Nyasha Nicole, Li, Xueqing, Nhachi, Charles, Masimirembwa, Collen, Thelingwani, Roslyn Stella“…Racemic praziquantel (PZQ) is the drug of choice for the treatment of schistosomiasis. R‐Praziquantel (R‐PZQ) has been shown as the therapeutic form, whereas S‐PZQ is less efficacious and responsible for the bitter taste of the tablet. …”
Publicado 2020
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3218por Cha, Seungman, Hong, Sung-Tae, Lee, Jin-Su, Jeong, Hoo Gn, Kwon, In-Sun, Saed, Abd Al Wahab, Elhag, Mousab Siddig, Ismail, Hassan Ahmed Hassan Ahmed, Amin, Mutamad, Lee, Young-Ha“…This clearly points to the importance of repeated MDA interventions in endemic areas, which will eventually contribute to schistosomiasis elimination.…”
Publicado 2020
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3219“…BACKGROUND: Schistosomiasis is caused by Schistosoma mansoni and S. haematobium in Africa. …”
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3220por Ammar, Amany Ibrahim, Afifi, Amira Fathy, Essa, Abdallah, Galal-Khallaf, Asmaa, Mokhtar, Mostafa Mohamed, Shehab-Eldeen, Somaia, Rady, Amany Ahmed“…BACKGROUND: Schistosomiasis is a tropical parasitic disease treated exclusively with praziquantel (PZQ). …”
Publicado 2020
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