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3281por Ngwa, Ambe Fabrice, Tanyi Bobga, Pride, Nsongmayi, Ekwi Damian, Yememe Yememe, Gedeon Schadrack, Ngong Nyeme, Judith, Isah, Mohamed, Ashu, Ebai Christabel, Ebai, Calvin Bisong“…BACKGROUND: Schistosomiasis remains a major public health concern in sub-Saharan Africa. …”
Publicado 2023
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3282por Mitalo, Nancy S., Waiganjo, Naomi N., Mokua Mose, John, Bosire, David O., Oula, James O., Orina Isaac, Alfred, Nyabuga Nyariki, James“…INTRODUCTION: Human African trypanosomiasis (HAT) and schistosomiasis are neglected parasitic diseases found in the African continent. …”
Publicado 2023
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3283por Carlos Gaspar, Juan, Moeller, Tyler, Buchta, Jessica, Nieto, Monica, Espinoza, Nereyda, Castillo, Rosa, Nunez, Rosa“…These primates have also been used to study leishmaniasis, schistosomiasis, tuberculosis and various types of enteric infections. …”
Publicado 2023
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3284por Waisberg, Michael, Lobo, Francisco P, Cerqueira, Gustavo C, Passos, Liana KJ, Carvalho, Omar S, Franco, Glória R, El-Sayed, Najib M“…BACKGROUND: The parasitic trematode Schistosoma mansoni is one of the major causative agents of Schistosomiasis, a disease that affects approximately 200 million people, mostly in developing countries. …”
Publicado 2007
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3285por Venancio, Thiago M, DeMarco, Ricardo, Almeida, Giulliana T, Oliveira, Katia C, Setubal, João C, Verjovski-Almeida, Sergio“…BACKGROUND: Schistosoma mansoni is a blood helminth parasite that causes schistosomiasis, a disease that affects 200 million people in the world. …”
Publicado 2007
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3286“…Schistosomes, parasitic platyhelminths that cause schistosomiasis, express two β subunit subtypes: a structurally conventional β subunit and a variant β subunit with unusual functional properties. …”
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3287por Xue, Xiangyang, Sun, Jun, Zhang, Qingfeng, Wang, Zhangxun, Huang, Yufu, Pan, Weiqing“…BACKGROUND: Schistosomiasis japonica remains a major public health problem in China. …”
Publicado 2008
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3288por Gatlin, Michael R., Black, Carla L., Mwinzi, Pauline N., Secor, W. Evan, Karanja, Diana M., Colley, Daniel G.“…BACKGROUND: The immunologic findings that most consistently correlate with resistance in human schistosomiasis are high levels of IgE and low levels of IgG4. …”
Publicado 2009
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3289por Quack, Thomas, Knobloch, Jürgen, Beckmann, Svenja, Vicogne, Jérome, Dissous, Colette, Grevelding, Christoph G.“…BACKGROUND: Schistosomiasis (bilharzia) is a parasitic disease of worldwide significance affecting human and animals. …”
Publicado 2009
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3290por Berriman, Matthew, Haas, Brian J., LoVerde, Philip T., Wilson, R. Alan, Dillon, Gary P., Cerqueira, Gustavo C., Mashiyama, Susan T., Al-Lazikani, Bissan, Andrade, Luiza F., Ashton, Peter D., Aslett, Martin A., Bartholomeu, Daniella C., Blandin, Gaelle, Caffrey, Conor R., Coghlan, Avril, Coulson, Richard, Day, Tim A., Delcher, Art, DeMarco, Ricardo, Djikeng, Appoliniare, Eyre, Tina, Gamble, John A., Ghedin, Elodie, Gu, Yong, Hertz-Fowler, Christiane, Hirai, Hirohisha, Hirai, Yuriko, Houston, Robin, Ivens, Alasdair, Johnston, David A., Lacerda, Daniela, Macedo, Camila D., McVeigh, Paul, Ning, Zemin, Oliveira, Guilherme, Overington, John P., Parkhill, Julian, Pertea, Mihaela, Pierce, Raymond J., Protasio, Anna V., Quail, Michael A., Rajandream, Marie-Adèle, Rogers, Jane, Sajid, Mohammed, Salzberg, Steven L., Stanke, Mario, Tivey, Adrian R., White, Owen, Williams, David L., Wortman, Jennifer, Wu, Wenjie, Zamanian, Mostafa, Zerlotini, Adhemar, Fraser-Liggett, Claire M., Barrell, Barclay G., El-Sayed, Najib M.“…Schistosoma mansoni is responsible for the neglected tropical disease schistosomiasis that affects 210 million people in 76 countries. …”
Publicado 2009
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3291por Fitzpatrick, Jennifer M., Peak, Emily, Perally, Samirah, Chalmers, Iain W., Barrett, John, Yoshino, Timothy P., Ivens, Alasdair C., Hoffmann, Karl F.“…Towards this end, we present a combinatorial, bioinformatics-led approach, employing both statistical and network analyses of transcriptomic data, for identifying new immunoprophylactic and therapeutic lead targets to combat schistosomiasis. METHODOLOGY/PRINCIPAL FINDINGS: Utilisation of a Schistosoma mansoni oligonucleotide DNA microarray consisting of 37,632 elements enabled gene expression profiling from 15 distinct parasite lifecycle stages, spanning three unique ecological niches. …”
Publicado 2009
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3292por He, YunKun, Li, Jia, Zhuang, WenJia, Yin, Lan, Chen, ChunXia, Li, Jun, Chi, FengLi, Bai, YanShuang, Chen, Xiao-Ping“…Furthermore, the ability of schistosomiasis to negatively regulate the onset of collagen-induced arthritis is associated with a dominant as well as long-lasting Th2 response at the initiation and development of autoimmune joint and systemic inflammation.…”
Publicado 2010
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3293por Ziegelbauer, Kathrin, Steinmann, Peter, Zhou, Hui, Du, Zun-Wei, Jiang, Jin-Yong, Fürst, Thomas, Jia, Tie-Wu, Zhou, Xiao-Nong, Utzinger, Jürg“…For chronic diseases such as soil-transmitted helminthiasis and schistosomiasis, it has been suggested that a patient-based quality of life (QoL) approach should be considered for a more accurate appraisal of disability weights. …”
Publicado 2010
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3294“…It developed rapid strip diagnostic tests for locally prevalent diseases including schistosomiasis and HIV, and reported $2 million (USD) in revenue in 2009. …”
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3295por Xu, Jing, Peeling, Rosanna W., Chen, Jia-Xu, Wu, Xiao-Hua, Wu, Zhong-Dao, Wang, Shi-Ping, Feng, Ting, Chen, Shao-Hong, Li, Hao, Guo, Jia-Gang, Zhou, Xiao-Nong“…CONCLUSIONS/SIGNIFICANCE: Most evaluated tests had acceptable performance characteristics and could make an impact on the schistosomiasis control programs in P.R. China. Three tests with the highest sensitivity, specificity and greatest ease of use, were selected for further evaluation in field settings.…”
Publicado 2011
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3296por Andrade, Luiza F, Nahum, Laila A, Avelar, Lívia GA, Silva, Larissa L, Zerlotini, Adhemar, Ruiz, Jerônimo C, Oliveira, Guilherme“…BACKGROUND: Schistosomiasis remains an important parasitic disease and a major economic problem in many countries. …”
Publicado 2011
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3297“…In particular, programmes targeting lymphatic filariasis, onchocerciasis, schistosomiasis, trachoma and soil transmitted helminth infections have expanded to treat 887. 8 million people in 2009. …”
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3298por Farias, Leonardo Paiva, Rodrigues, Dunia, Cunna, Vinicius, Rofatto, Henrique Krambeck, Faquim-Mauro, Eliana L., Leite, Luciana C. C.“…CONCLUSIONS: Our results suggest that members of the SmVAL family do present allergic properties; however, this varies significantly and therefore should be considered in the design of a schistosomiasis vaccine. Additionally, the murine model of airway inflammation proved to be useful in the investigation of allergic properties of potential vaccine candidates.…”
Publicado 2012
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3299por Yang, Jianmei, Fu, Zhiqiang, Feng, Xingang, Shi, Yaojun, Yuan, Chunxiu, Liu, Jinming, Hong, Yang, Li, Hao, Lu, Ke, Lin, Jiaojiao“…The results provide valuable information for increased understanding of host-schistosome interactions, and for control of schistosomiasis.…”
Publicado 2012
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3300por Fitzsimmons, Colin M., Jones, Frances M., Stearn, Alex, Chalmers, Iain W., Hoffmann, Karl F., Wawrzyniak, Jakub, Wilson, Shona, Kabatereine, Narcis B., Dunne, David W.“…We expressed SmTAL1 (Sm22.6), SmTAL2, 3, 4, 5 and 13 as recombinant proteins and measured IgE and IgG4 in 200 infected males (7–60 years) from a schistosomiasis endemic region in Uganda. For SmTAL1 and 3 (transcribed in schistosomula through adult-worms and adult-worms, respectively) and SmTAL5 (transcribed in cercariae through adult-worms), detectable IgE responses were rare in 7–9 year olds, but increased with age. …”
Publicado 2012
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