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  1. 24301
    por Zhao, Weijie
    Publicado 2020
    “…In the past two decades, scientists have been able to use engineered living systems to produce many kinds of products from bioplastics to drugs, to construct a minimal bacterium with a fully synthetic genome and to store huge amount of information within a cell. …”
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    A forum on synthetic biology: meet the great challenges with new technology
  2. 24302
    “…During the past years, many scientists have discovered that certain molecules or biomarkers participating in this EMT process are able to predict the severity of the cancer and this is helping clinicians to manage treatments. …”
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    Prognostic Factors Involved in the Epithelial–Mesenchymal Transition Process in Colorectal Cancer Have a Preponderant Role in Oxidative Stress: A Systematic Review and Meta-Analysis
  3. 24303
    “…INTRODUCTION: Many scientists were engaged in the problems of studying the runoff formation conditions from the water-intake basins area and studying the operation of rainwater drainage systems and its calculations. …”
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    Mathematical model for the duration of runoff formation determined from the road surface
  4. 24304
    “…Methods: Expert reference group meetings informed the development of Actissist and design of subsequent trials, which included individuals with lived experience of psychosis, clinicians, academics, computer scientists and software engineers. Person-centered stakeholder involvement was promoted using focus groups and qualitative interviews prior to the development of the app, which informed version one of Actissist. …”
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    Developing a Theory-Informed Smartphone App for Early Psychosis: Learning Points From a Multidisciplinary Collaboration
  5. 24305
    “…Interestingly, goose fatty liver can reach 8–10 times the weight of normal liver with no overt pathological symptoms, suggesting that there are some protective mechanisms. Scientists have indicated that gut microbiota participate in the formation of non-alcoholic fatty liver disease in human and mammalian animals. …”
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    GC-TOF-MS-Based Metabolomics Analyses of Liver and Intestinal Contents in the Overfed vs. Normally-Fed Geese
  6. 24306
    “…SIMPLE SUMMARY: Mice is the most used species in the biomedical research laboratory setting. Scientists are constantly striving to find new tools to assess their welfare, in order to ameliorate husbandry conditions, leading to a better life and scientific data. …”
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    Quantification of Hair Corticosterone, DHEA and Testosterone as a Potential Tool for Welfare Assessment in Male Laboratory Mice
  7. 24307
    “…This cause prompted scientists to investigate alternative new molecules against bacterial strains. …”
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    Component Composition and Antimicrobial Activity of CO(2) Extract of Portulaca oleracea, Growing in the Territory of Kazakhstan
  8. 24308
    “…Given the widespread use of kratom and the extensive media attention it is receiving, it is important for physicians, scientists and policy makers to be knowledgeable about the subject. …”
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    Kratom policy: The challenge of balancing therapeutic potential with public safety
  9. 24309
    “…Due to this facet selectivity, crystalline structures with very specific geometries can be grown in one, two, or three dimensions; controlled oriented attachment suddenly becomes a tool for material scientists to grow architectures that cannot be reached by any other means. …”
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    Oriented Attachment: From Natural Crystal Growth to a Materials Engineering Tool
  10. 24310
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    A validated photonumeric scale for infraorbital dark circles and its application in evaluating the efficacy of a cosmetic treatment product in a split‐face randomized clinical trial
  11. 24311
    “…In turn, the tool itself was also refined through an iterative consultation process between experts (both ethicists and scientists) and stakeholders. ABSTRACT: Assisted reproductive technologies (ARTs) can make a difference in biodiversity conservation. …”
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    An Ethical Assessment Tool (ETHAS) to Evaluate the Application of Assisted Reproductive Technologies in Mammals’ Conservation: The Case of the Northern White Rhinoceros (Ceratotherium simum cottoni)
  12. 24312
    “…ABSTRACT: The tumor-specific targeting of chemotherapeutic agents for specific necrosis of cancer cells without affecting the normal cells poses a great challenge for researchers and scientists. Though extensive research has been carried out to investigate chemotherapy-based targeted drug delivery, the identification of the most promising strategy capable of bypassing non-specific cytotoxicity is still a major concern. …”
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    Recent Advancements in Stimuli Responsive Drug Delivery Platforms for Active and Passive Cancer Targeting
  13. 24313
    “…BACKGROUND: Madagascar is famous for its extremely rich biodiversity; the island harbors predominantly endemic and threatened communities meriting special attention from biodiversity scientists. Continuing ongoing efforts to inventory the Malagasy ant fauna, we revise the species currently placed in the myrmicine genus Aphaenogaster Mayr. …”
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    Taxonomic revision of the Malagasy Aphaenogaster swammerdami group (Hymenoptera: Formicidae)
  14. 24314
    “…How species will respond to ongoing and future climate change is one of the most important questions facing biodiversity scientists today. The fossil record provides unparalleled insight into past ecological and evolutionary responses to climate change, but the resource remains virtually untapped for many organisms. …”
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    Divergent morphological responses to millennia of climate change in two species of bats from Hall’s Cave, Texas, USA
  15. 24315
    “…This metabolism prevents toxic buildup of the insecticide, which would otherwise be lethal to the mosquitoes. Scientists have identified a variety of changes to mosquito genes that are responsible for insecticide degradation and excretion. …”
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    From Global to Local—New Insights into Features of Pyrethroid Detoxification in Vector Mosquitoes
  16. 24316
    “…However, to date, the role of excipients in these formulations on skin delivery of actives has received little attention from scientists in the field. Monitoring skin absorption of both drug and vehicle may provide insights into the mechanism by which excipients promote permeation and may facilitate the design of effective and safer products. …”
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    In Vitro–In Vivo Correlation in Dermal Delivery: The Role of Excipients
  17. 24317
    “…SIMPLE SUMMARY: The increasing prevalence of worldwide obesity and growing awareness of its negative consequences are forcing scientists to take a new view of nutrition and search for new diets. …”
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    The Long-Term Effects of High-Fat and High-Protein Diets on the Metabolic and Endocrine Activity of Adipocytes in Rats
  18. 24318
    “…Honourable Prime Minister inspired, motivated and appreciated the strides made by Indian Scientists for nation building, especially the role of CSIR-NPL and impact of metrology for self-reliant India. …”
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    75th Foundation Day of CSIR-National Physical Laboratory: Celebration of Achievements in Metrology for National Growth
  19. 24319
    “…While this observation has generally not impacted clinical imaging in individuals with SCD, it has led to resistance for some sickle cell studies within the engineering community among some imaging scientists as this early observation has never been rigorously shown to be unconcerning. …”
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    Safety of 3 Tesla Magnetic Resonance Imaging in Patients with Sickle Cell Disease
  20. 24320
    “…It seems warranted with more active involvement of scientists and independent organisations without conflicts of interest in the guideline development process.…”
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    EMA and FDA psychiatric drug trial guidelines: assessment of guideline development and trial design recommendations
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