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  1. 1441
    “…Time-series data for a number of ecosystems reveal high spatio-temporal variability superimposed on secular trends traceable to nutrient over-enrichment. …”
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    Long-term trends, current status, and transitions of water quality in Chesapeake Bay
  2. 1442
    “…This case review study will examine work-related fatal injury (WRFI) to: i) determine their burden, rates and distribution; ii) identify high-risk groups, causes and circumstances; iii) analyse secular trends, and iv) examine the impact of historic occupational safety legislative reform. …”
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    Identifying opportunities to prevent work-related fatal injury in New Zealand using 40 years of coronial records: protocol for a retrospective case review study
  3. 1443
    “…We will include one Trust which has not expressed interest in the PQIP for comparison and to explore the role of secular trend in any changes in practice. We will use semi-structured interviews (up to 144 in Trusts and 12 with the project team), non-participant observations (up to 150  hours) and documentary analysis. …”
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    Qualitative process evaluation of the Perioperative Quality Improvement Programme (PQIP): study protocol
  4. 1444
    “…Difference-in-differences (DID) analysis incorporating equivalent data from the Scottish Morbidity Record was used to control for secular trends. The outcomes were 30-day and 365-day mortality, 30-day re-admission, time to operation, and acute length of stay. …”
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    Pay for performance and hip fracture outcomes: an interrupted time series and difference-in-differences analysis in England and Scotland
  5. 1445
    “…Second, we use literature-based estimates of adverse event rates, variant allele frequencies, secular death rates, and costs to construct a discrete event simulation that estimates the expected benefit of having an individual’s genetic data in the electronic health record after an indication has occurred. …”
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    A Decision-Theoretic Approach to Panel-Based, Preemptive Genotyping
  6. 1446
    “…We, therefore, evaluated the secular trends in survival improvement of leukemia patients from 1973 through 2014, using Surveillance Epidemiology and End-Result Survey Program (SEER) data. …”
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    Racial/ethnic, age and sex disparities in leukemia survival among adults in the United States during 1973-2014 period
  7. 1447
    “…However, further studies are needed to confirm whether rates of aMCI have changed in other populations, and how aMCI rates are related to secular trends in dementia risk factors.…”
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    A Birth Cohort Analysis of Amnestic Mild Cognitive Impairment Incidence in the Einstein Aging Study (EAS) Cohort
  8. 1448
    “…ELIGIBILITY CRITERIA: Studies of open population based cohorts, diabetes registries, and administrative and health insurance databases on secular trends in the incidence of total diabetes or type 2 diabetes in adults were included. …”
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    Trends in incidence of total or type 2 diabetes: systematic review
  9. 1449
    “…We seek to quantify and close the budget of secular changes in TWS over the span of the GRACE satellite mission (2003–2016). …”
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    Water Storage Trends in High Mountain Asia
  10. 1450
    “…We used multivariable mixed-effects Poisson regression modeling to estimate rate ratios (RR) with 95% confidence intervals (CIs) adjusted for potential confounders and secular trends. RESULTS: In Texas, county-years with high drilling activity had 10% increased rates of chlamydia (RR, 1.10; 95% CI, 1.04–1.17) and 15% increased rates of gonorrhea (RR, 1.15; 95% CI, 1.04–1.28), compared with county-years with no drilling. …”
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    A Multiregion Analysis of Shale Drilling Activity and Rates of Sexually Transmitted Infections in the United States
  11. 1451
    “…Thirty-four full genome sequences were downloaded from GenBank and divided into three non-mutually exclusive groups, namely, worldwide, Genogroup 2 and China, to cover different ranges of secular and spatial trends. Each dataset was then divided into different alignments by different genes for likelihood mapping and phylogenetic analysis. …”
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    Evolutionary characterization of the emerging porcine epidemic diarrhea virus worldwide and 2014 epidemic in Taiwan
  12. 1452
    “…With the mesosystem in place, CLABSI rates ranged from 0.4 to 0.7 per 1,000 central line days during the post-intervention period. Adjusting for secular trends, we observed a statistically significant decrease in the post versus pre-intervention CLABSI rate of 71%. …”
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    Reduction of Central Line-associated Bloodstream Infection Through Focus on the Mesosystem: Standardization, Data, and Accountability
  13. 1453
    “…The system is influenced by secular sociocultural practices and environmental conditions affecting product properties. …”
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    Traditional milk transformation schemes in Côte d’Ivoire and their impact on the prevalence of Streptococcus bovis complex bacteria in dairy products
  14. 1454
    “…CONCLUSION: While an influence of secular trends cannot be excluded, the COVID-19 outbreak coincided with a comparatively significant rise in initial and recurrent stroke admissions at this Ghanaian tertiary hospital. …”
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    COVID-19 and stroke: Experience in a Ghanaian healthcare system
  15. 1455
    “…These findings suggest that religious and secular networks differ in their longevity and have divergent influences on a woman's fertility. …”
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    Church attendance and alloparenting: an analysis of fertility, social support and child development among English mothers
  16. 1456
    “…Therefore, in this study, we analyzed the secular stroke status in Sichuan province to help explore the potential reasons for geographic disparity. …”
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    Comparison and Analysis of Epidemiologic Characteristics of Stroke in Sichuan Province, China
  17. 1457
    “…Cores and trenches drilled or dug in religious and secular buildings in the hilltop town of Bergamo (northern Italy) were investigated by means of micro/macrobotanical and pedochemical analysis to unravel the cultural vegetation history of the area during ca. seven centuries across the Bronze—Iron Ages. …”
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    Life on a hilltop: vegetation history, plant husbandry and pastoralism at the dawn of Bergamo-Bergomum (northern Italy, 15th to 7th century bc)
  18. 1458
    “…Although less prevalent than in our earlier study, there was no evidence of a secular decline in tobacco content during this study period. …”
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    Tobacco and tobacco branding in films most popular in the UK from 2009 to 2017
  19. 1459
    “…Interrupted time series analysis will be used to identify change in the rate of identification of AUDs beyond that observed due to secular trends or by chance. The integrated model will be finalised for future implementation and larger-scale evaluation. …”
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    Adaptation and piloting of an integrated intervention model for alcohol use disorders in primary healthcare in rural Tanzania: a study protocol
  20. 1460
    “…BACKGROUND: Limited population-based studies have investigated the secular trend of prevalence of gestational diabetes mellitus (GDM) in mainland China. …”
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    Trends in prevalence of gestational diabetes mellitus in Zhejiang Province, China, 2016–2018
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