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  1. 1641
    “…Design Age stratified time series analysis of daily mortality with Poisson regression models adjusted for the effects of temperature, humidity, day of week, respiratory epidemics, and secular mortality trends, applied to an intervention and control community. …”
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    Evaluation of interventions to reduce air pollution from biomass smoke on mortality in Launceston, Australia: retrospective analysis of daily mortality, 1994-2007
  2. 1642
    “…CONCLUSIONS: De-tabooing dying control is an assumed secular process starting with open awareness contexts of dying half a century ago, and continuing with the growth of the palliative care movement and later euthanasia and PAS legislation.…”
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    De-tabooing dying control - a grounded theory study
  3. 1643
    “…The objective of our study was to determine secular trends in the prevalence of central obesity (WC ≥ 90 cm for men and ≥ 80 cm for women) among Chinese adults with normal BMI from 1993 to 2009 and to examine the impact of performance of combined BMI and WC on the prevalence of obesity in Chinese adults. …”
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    Increasing trends in central obesity among Chinese adults with normal body mass index, 1993–2009
  4. 1644
    “…INTRODUCTION: The objective of this study was to clarify secular changes in the prevalence and cumulative incidence of vertebral fractures (VFx) among the general inhabitants of Miyama, a rural Japanese community. …”
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    Cumulative incidence and changes in the prevalence of vertebral fractures in a rural Japanese community: a 10-year follow-up of the Miyama cohort
  5. 1645
    “…Before-after studies ignore underlying secular trends and may overestimate the impact of interventions. …”
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    Impact of STROBE Statement Publication on Quality of Observational Study Reporting: Interrupted Time Series versus Before-After Analysis
  6. 1646
    “…The specific aims were to describe secular trends in oral health status regarding number of remaining teeth and also to describe differences in socio-economic status, among 38- and 50-year-old women, over a 36-year period. …”
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    Trends in tooth loss in relation to socio-economic status among Swedish women, aged 38 and 50 years: repeated cross-sectional surveys 1968-2004
  7. 1647
    “…The directional distribution method with two standard deviations of ellipse was applied to measure the size and the movement of the epidemic. RESULTS: The secular trend showed that the number of severe EV cases peaked in 2008, and the number of mild EV cases was significantly correlated with that of severe ones occurring in the same week [r = 0.553, p < 0.01]. …”
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    Spatio-temporal analysis on enterovirus cases through integrated surveillance in Taiwan
  8. 1648
    “…We estimated the prevalence of AD drugs before, during and after pregnancy, and secular trends across the study period (1999–2009), using linear regression. …”
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    Anti-diabetic drug utilization of pregnant diabetic women in us managed care
  9. 1649
    “…Our specific aims were to (i) estimate the recent secular trends, (ii) assess the disease burden, and (iii) define the demographics and comorbid conditions of AP in hospitalized children within the United States. …”
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    Epidemiology of Acute Pancreatitis in Hospitalized Children in the United States from 2000–2009
  10. 1650
    “…This increased in-facility births from 30%in 2005 to 73% in 2012 however, decline in maternal mortality follows a secular trend. Dysfunctional referral services can contribute to poor programme impact on outcomes. …”
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    Quality of Obstetric Referral Services in India's JSY Cash Transfer Programme for Institutional Births: A Study from Madhya Pradesh Province
  11. 1651
    “…A systematic assessment of recent evidence is warranted in light of secular changes in epidemiology, pathogens, and the uncertainties around the incidence and risk factors of community-onset sepsis. …”
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    Community-onset sepsis and its public health burden: protocol of a systematic review
  12. 1652
    “…In light of the interrelation between motor and cognitive development and the predictive value of the former for the latter, the secular decline observed in motor coordination ability as early as preschool urges identification of interventions that may jointly impact motor and cognitive efficiency. …”
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    Deliberate Play and Preparation Jointly Benefit Motor and Cognitive Development: Mediated and Moderated Effects
  13. 1653
    “…A negative binominal regression model that included the effect of time was used to calculate rates and rate ratios (RRs) and 95% confidence intervals (CIs) for RV-AGE and overall AGE between periods, after adjusting for age, seasonality and secular trends. Analyses were conducted for all ages combined and age stratified. …”
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    Population-Level Impact of Ontario’s Infant Rotavirus Immunization Program: Evidence of Direct and Indirect Effects
  14. 1654
    “…Nondifferential impacts on stunting were likely due to rapid positive secular trends in Bangladesh. Accelerating linear growth further could require accompanying interventions. …”
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    Combining Intensive Counseling by Frontline Workers with a Nationwide Mass Media Campaign Has Large Differential Impacts on Complementary Feeding Practices but Not on Child Growth: Results of a Cluster-Randomized Program Evaluation in Bangladesh(1)(2)(3)
  15. 1655
    “…Additional TB notifications were calculated by comparing numbers of cases notified during the intervention with those notified before the intervention, then adjusting for secular trends in notification. RESULTS: We screened 2,022,127 people for TB symptoms during the intervention, tested 59,838 with smear microscopy and detected 5,046 people with smear-positive TB. …”
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    An Evaluation of Passive and Active Approaches to Improve Tuberculosis Notifications in Afghanistan
  16. 1656
    “…We additionally defined growth faltering as fall in Z score between 3 months and 21 months of age. FINDINGS: We noted secular improvements in all postnatal growth parameters (except weight-for-length), accompanied by declines over time in seasonal variability. …”
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    Growth faltering in rural Gambian children after four decades of interventions: a retrospective cohort study
  17. 1657
    “…BACKGROUND: Circadian disruption caused by exposure to light at night (LAN) has been proposed as a risk factor for breast cancer and a reason for secular increases in incidence. Studies to date have largely been ecological or case-control in design and findings have been mixed. …”
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    Domestic light at night and breast cancer risk: a prospective analysis of 105 000 UK women in the Generations Study
  18. 1658
    “…CONCLUSIONS: There was continuing evolution in carried NVTs six years after PCV13 introduction which, in addition to being vaccine-driven, could also reflect natural secular changes in certain NVTs. This poses challenges in predicting future trends in IPD. …”
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    Pneumococcal carriage in children and their household contacts six years after introduction of the 13-valent pneumococcal conjugate vaccine in England
  19. 1659
    “…BACKGROUND: Elevated serum uric acid (sUA) concentrations are common in the general population and are associated with chronic metabolic conditions and adverse clinical outcomes. We evaluated secular trends in the burden of hyperuricaemia from 2006–2014 within the Irish health system. …”
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    Temporal trends in hyperuricaemia in the Irish health system from 2006-2014: A cohort study
  20. 1660
    Publicado 2018
    “…BACKGROUND: Change in the prevalence of raised blood pressure could be due to both shifts in the entire distribution of blood pressure (representing the combined effects of public health interventions and secular trends) and changes in its high-blood-pressure tail (representing successful clinical interventions to control blood pressure in the hypertensive population). …”
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    Contributions of mean and shape of blood pressure distribution to worldwide trends and variations in raised blood pressure: a pooled analysis of 1018 population-based measurement studies with 88.6 million participants
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