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  1. 1701
    “…In this study, we aimed to report the prevalence of NWCO in the general Chinese adults and its secular trend from 1993 to 2011. The comorbid cardiometabolic risk of NWCO was also explored. …”
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    Temporal trends in normal weight central obesity and its associations with cardiometabolic risk among Chinese adults
  2. 1702
    “…Multivariable logistic and linear mixed effects regression analysis were used, accounting for secular trends, within hospital correlation and over time correlation, and adjusting for a maternal comorbidity index, hospital annual birth volume, and level of care. …”
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    Effect of implementation of the MORE(OB) program on adverse maternal and neonatal birth outcomes in Ontario, Canada: a retrospective cohort study
  3. 1703
    “…We adjusted for inflation rate, age, gender and secular and seasonal trends. RESULTS: Cost of smoking did not increase above the rate of inflation. …”
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    Smokers’ strategies across social grades to minimise the cost of smoking in a period with annual tax increases: evidence from a national survey in England
  4. 1704
    “…METHODS: People with JME were identified from a large database of individuals with epilepsy, which includes detailed retrospective information on AED use. We assessed secular changes in AED use and calculated rates of response (12‐month seizure freedom) and adverse drug reactions (ADRs) for the five most common AEDs. …”
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    Comparative effectiveness of antiepileptic drugs in juvenile myoclonic epilepsy
  5. 1705
    “…CONCLUSION: Across these primary stroke care centres in Australia, a secular trend towards shorter door-to-needle times across both intervention and control hospitals was evident, however the TIPS (Thrombolysis ImPlementation in Stroke) intervention showed no overall effect on door-to-needle times in the randomised comparison. …”
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    Door-to-needle time for thrombolysis: a secondary analysis of the TIPS cluster randomised controlled trial
  6. 1706
    “…OBJECTIVES: To describe the prevalence of general (body mass index (BMI) ≥30 kg/m(2)) and abdominal (waist circumference women >88 cm, men >102 cm) obesity in Tromsø 7 (2015–2016), and the secular change from Tromsø 6 (2007–2008). Furthermore, to study longitudinal changes in body weight and waist circumference from Tromsø 6 to Tromsø 7. …”
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    Prevalence of general and abdominal obesity in 2015–2016 and 8-year longitudinal weight and waist circumference changes in adults and elderly: the Tromsø Study
  7. 1707
    “…We aimed to analyze the secular trends in the incidence and distribution of candidemia in ICUs over 12-years using data from the Korean National Healthcare-Associated Infections Surveillance System (KONIS). …”
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    Trends in the Epidemiology of Candidemia in Intensive Care Units From 2006 to 2017: Results From the Korean National Healthcare-Associated Infections Surveillance System
  8. 1708
    “…OBJECTIVES: Using routinely collected hospital data, this study explored secular trends over time in breast feeding initiation in a large Australian sample. …”
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    Relationship between obesity and lower rates of breast feeding initiation in regional Victoria, Australia: an 8-year retrospective panel study
  9. 1709
    “…Before the intervention, both settings showed secular trends toward smaller-quantity prescriptions. …”
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    Effect of an Electronic Health Record “Nudge” on Opioid Prescribing and Electronic Health Record Keystrokes in Ambulatory Care
  10. 1710
    “…Over the years of the study, only among the Ethiopian immigrants were there large fluctuations in suicide rates: a decrease (1992–2001), followed by an increase (2001–2006), and then a progressive decrease (from 2006). The secular changes differed greatly according to age. …”
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    Suicide rates and risk factors for suicide among Israeli immigrants from Ethiopia (1985–2017)
  11. 1711
    “…BACKGROUND: Most studies on secular trends in body mass index (BMI) are cross-sectional and the few longitudinal studies have typically only investigated changes over time in mean BMI trajectories. …”
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    Changes over time in latent patterns of childhood-to-adulthood BMI development in Great Britain: evidence from three cohorts born in 1946, 1958, and 1970
  12. 1712
    “…Difference‐in‐differences analyses controlled for secular trends with stratification by estimated risk and adjustment for risk factors, ED physician and facility. …”
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    Graded Coronary Risk Stratification for Emergency Department Patients With Chest Pain: A Controlled Cohort Study
  13. 1713
    “…BACKGROUND: Given that recent studies report negative secular declines in physical fitness, associations between fitness and cognition in childhood are strongly discussed. …”
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    Associations between measures of physical fitness and cognitive performance in preschool children
  14. 1714
    “…CONCLUSIONS: VHA’s Whole Health national pilot program was associated with greater reductions in prescribed opioid doses compared to secular trends associated with conventional care, especially when Veterans were connected with complementary and integrative health therapies. …”
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    Effectiveness of a whole health model of care emphasizing complementary and integrative health on reducing opioid use among patients with chronic pain
  15. 1715
    “…Event study and difference-in-difference models allowed us to separate the impact of the pandemic, experienced by the pandemic cohort only, from secular and seasonal changes experienced by all cohorts. …”
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    The COVID-19 pandemic’s impact on mental health care use among Norwegian students in higher education: a nation-wide register-based pre-post cohort study
  16. 1716
    “…This study is designed to assess the epidemiological patterns of hand OA from 1990 to 2019 and analyze its secular trends based on sex, age, and socio-demographic index (SDI) at global, regional, and national levels. …”
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    Epidemiological trends of hand osteoarthritis from 1990 to 2019: Estimates from the 2019 Global Burden of Disease study
  17. 1717
    “…CONCLUSION: The virtual approach developed in the present study that mixes two major facial coloured phenotypes seems at the crossroad of both genetic backgrounds and the secular desire of a modified appearance. Nonetheless, this methodology could afford, at the individual level in total confidentiality, a great help to subjects exposed to some facial skin disorders or afflictions.…”
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    Virtual approach of the aesthetical fit between hair colours and skin tones in women of different ethnical origin backgrounds
  18. 1718
    “…We quantified representation changes at each point as the ratio of representation in the later stage to earlier stage (representation ratio [RR]). We assessed secular trends in the representation ratio through univariate linear regression. …”
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    The leaky pipeline of diverse race and ethnicity representation in academic science and technology training in the United States, 2003–2019
  19. 1719
    “…BACKGROUND: While the United Kingdom National Health Service aimed to reduce social inequalities in the provision of joint replacement, it is unclear whether these gaps have reduced. We describe secular trends in the provision of primary hip and knee replacement surgery between social deprivation groups. …”
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    Inequalities in provision of hip and knee replacement surgery for osteoarthritis by age, sex, and social deprivation in England between 2007–2017: A population-based cohort study of the National Joint Registry
  20. 1720
    “…The aim of the study was to analyze the secular trend of hypertension prevalence in the PURE Poland cohort study over 9 years of observation and to analyze factors associated with controlled HT. …”
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    Sociodemographic and behavioral factors associated with controlled hypertension after 9 years of observation of a PURE Poland cohort study
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