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  1. 2161
    “…Cellular senescence leads to the depletion of myogenic progenitors and decreased regenerative capacity. …”
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    Reversine ameliorates hallmarks of cellular senescence in human skeletal myoblasts via reactivation of autophagy
  2. 2162
    “…METHODS: We performed a senescence-associated β-galactosidase staining assay to confirm cellular senescence in human dermal fibroblasts (HDFs). …”
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    Ginsenoside Rb2 suppresses cellular senescence of human dermal fibroblasts by inducing autophagy
  3. 2163
    por Liu, Hai, Li, Yufei, Peng, Ting, Xue, Shaowu
    Publicado 2023
    “…Whether the membrane potential of plasma membrane could report senescence signal of plant tissues and cells is unclear. …”
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    Transmembrane potential, an indicator in situ reporting cellular senescence and stress response in plant tissues
  4. 2164
    “…This trade‐off between organismal mortality components would be mediated, at the cellular scale, by the accumulation of senescent cells. In this framework, damaged cells can either undergo apoptosis or enter senescence. …”
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    Modeling of senescent cell dynamics predicts a late‐life decrease in cancer incidence
  5. 2165
    “…Aging induces pathological alterations in organs, which promotes systemic senescence associated with age-related disease. Recently, it has become evident that senescence at the cellular level, cellular senescence, is a cause of chronic diseases through production of various secretory factors including proinflammatory cytokines, chemokines, and matrix metalloproteinases (MMPs), which is referred to the senescence-associated secretory phenotype (SASP). …”
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    Cellular senescence with SASP in periodontal ligament cells triggers inflammation in aging periodontal tissue
  6. 2166
    “…Molecular biomarkers for senescence were also quantified with FTO depletion in murine myotubes. …”
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    Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease
  7. 2167
    “…BACKGROUND: Due to their inherent role in cell function, long non‐coding ribonucleic acids (lncRNAs) mediate changes in the microenvironment, and thereby participate in the development of cellular senescence. AIMS: This study aimed to identify cellular senescence‐related lncRNAs that could predict the prognosis of liver cancer. …”
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    Cellular senescence‐related long noncoding ribonucleic acids: Predicting prognosis in hepatocellular carcinoma
  8. 2168
    “…Survival probability decreased with body size in both sexes, indicating a senescence pattern typical of long‐lived species or in populations with a low extrinsic mortality. …”
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    Life span, growth, senescence and island syndrome: Accounting for imperfect detection and continuous growth
  9. 2169
    “…The increased presence of senescent cells in different neurological diseases suggests the contribution of senescence in the pathophysiology of neurodegenerative disorders. …”
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    Microglia senescence is related to neuropathic pain–associated comorbidities in the spared nerve injury model
  10. 2170
    “…Nano plastics (NPs) have been a significant threat to human health and are known to cause premature endothelial senescence. Endothelial senescence is considered one of the primary risk factors contributing to numerous cardiovascular disorders. …”
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    SGLT2 inhibition ameliorates nano plastics-induced premature endothelial senescence and dysfunction
  11. 2171
    “…Senescent cells are characterized by their senescence-associated secretory phenotype that overproduces inflammatory and catabolic factors that hamper normal tissue homeostasis. …”
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    Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities
  12. 2172
    “…Twenty-six-week-old male, senescence-accelerated mouse resistant (SAMR) mice received the AIN-93G basal diet, while twenty-six-week-old male, senescence-accelerated mouse prone 8 (SAMP8) mice received the AIN-93G basal diet or a 2% TE powder-supplemented diet for ten weeks. …”
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    Effects of Turmeric Extract on Age-Related Skeletal Muscle Atrophy in Senescence-Accelerated Mice
  13. 2173
    “…Cellular senescence describes a state of permanent proliferative arrest in cells. …”
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    Defective NCOA4-dependent ferroptosis in senescent fibroblasts retards diabetic wound healing
  14. 2174
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    Cell senescence, loss of splicing, and lipid metabolism in TDP-43-related neurodegenerative processes
  15. 2175
    “…This study aimed to develop and validate a senescence-related signature for predicting the prognosis of breast cancer patients. …”
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    A senescence-related signature for predicting the prognosis of breast cancer: A bioinformatics analysis
  16. 2176
    “…SIMPLE SUMMARY: Melanoma is a dreadful type of skin cancer with a poor response to therapy. Senescent cells have been found to accumulate with age and may contribute to the occurrence and development of melanoma. …”
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    The Cross Talk between Cellular Senescence and Melanoma: From Molecular Pathogenesis to Target Therapies
  17. 2177
    “…One of the factors contributing to aging is telomere shortening, causing alterations in the protein protective complex named shelterin and replicative senescence. Here, we address the question of the link between this telomere shortening and the transcriptional changes occurring in senescent cells. …”
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    Senescence‐associated transcriptional derepression in subtelomeres is determined in a chromosome‐end‐specific manner
  18. 2178
    “…TGF-β induces senescence in embryonic tissues. Whether TGF-β in the hypoxic tumor microenvironment (TME) induces senescence in cancer and how the ensuing senescence-associated secretory phenotype (SASP) remodels the cellular TME to influence immune checkpoint inhibitor (ICI) responses are unknown. …”
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    TGF-β in the microenvironment induces a physiologically occurring immune-suppressive senescent state
  19. 2179
    “…Meanwhile, cellular senescence, one of the hallmarks of cancer, and its related prognostic genes signature can provide critical information for clinical decision-making. …”
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    Cellular senescence-related gene signature as a valuable predictor of prognosis in hepatocellular carcinoma
  20. 2180
    “…A machine learning algorithm-based prognostic signature was developed from six senescence-related genes including SERPINE1, FEN1, PDGFRB, SNCG, TCF3, and APOC3. …”
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    Senescence-related genes define prognosis, immune contexture, and pharmacological response in gastric cancer
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