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  1. 2481
    Materias: “…Special Feature: An Integrative View of Senescence in Nature…”
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    Why leveraging sex differences in immune trade‐offs may illuminate the evolution of senescence
  2. 2482
    “…Long-term culture of primary cells is characterized by functional and secretory changes, which ultimately result in replicative senescence. It is largely unclear how the metabolome of cells changes during replicative senescence and if such changes are consistent across different cell types. …”
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    Senescence-Associated Metabolomic Phenotype in Primary and iPSC-Derived Mesenchymal Stromal Cells
  3. 2483
    “…We also compared these senescence markers to previously analysed markers of inflammation for the same purpose. …”
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    Senescence and Inflammatory Markers for Predicting Clinical Progression in Parkinson’s Disease: The ICICLE-PD Study
  4. 2484
    “…Replicative senescent HDFs were assessed with senescence-associated β-galactosidase staining and the expression of senescence-related markers. …”
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    Extracellular Vesicles Derived from Senescent Fibroblasts Attenuate the Dermal Effect on Keratinocyte Differentiation
  5. 2485
    “…Homocysteine (Hcy) accelerates neuronal senescence and induces age-related neurodegenerative diseases. …”
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    Hydrogen Sulfide Inhibits Homocysteine-Induced Neuronal Senescence by Up-Regulation of SIRT1
  6. 2486
    “…The study was aimed at evaluation of the role of secondary oxidative stress in the stress-induced premature senescence (SIPS) of human fibroblasts induced by H(2)O(2). …”
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    Effect of antioxidants on the H(2)O(2)-induced premature senescence of human fibroblasts
  7. 2487
    “…Collectively, these results demonstrate that senescent cells contribute to changes in plasma EVs with age and suggest a new mechanism by which senescent cells can affect cellular functions throughout the body.…”
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    Cellular senescence contributes to age‐dependent changes in circulating extracellular vesicle cargo and function
  8. 2488
    “…The link between tendon stem/progenitor cells (TSPCs) senescence and tendon aging has been well recognized. …”
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    AQP1 modulates tendon stem/progenitor cells senescence during tendon aging
  9. 2489
    “…Strawberry shelf life is limited, and little is known about the postharvest regulation of senescence in different fruit tissues. Strawberry is classified as a non-climacteric fruit, yet it is known that ethylene affects strawberry ripening. …”
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    Continuous Exposure to Ethylene Differentially Affects Senescence in Receptacle and Achene Tissues in Strawberry Fruit
  10. 2490
    “…Of those, FAHD1 has recently been described as a regulator of mitochondrial function and senescence, in the context of mitochondrial dysfunction associated senescence (MiDAS). …”
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    Regulation of cellular senescence by eukaryotic members of the FAH superfamily – A role in calcium homeostasis?
  11. 2491
    “…Here, we demonstrate that RAP1 is required to protect telomeres in replicative senescent human cells. Downregulation of RAP1 in these cells, but not in young or dividing pre‐senescent cells, leads to telomere uncapping and fusions. …”
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    Human RAP1 specifically protects telomeres of senescent cells from DNA damage
  12. 2492
    “…Cellular senescence plays a role in the onset of age-related pathologies and in the loss of tissue homeostasis. …”
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    Unravelling Cellular Mechanisms of Stem Cell Senescence: An Aid from Natural Bioactive Molecules
  13. 2493
    “…This study identifies chronic IH as a trigger of senescence-like phenotype in preadipocytes. Together, our data suggest that OSA may be considered as a senescence-related disorder.…”
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    Chronic Intermittent Hypoxia Triggers a Senescence-like Phenotype in Human White Preadipocytes
  14. 2494
    “…BACKGROUND AND AIMS: Endothelial senescence is an important risk factor leading to atherosclerosis. …”
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    Quercetin Attenuates Atherosclerosis via Modulating Oxidized LDL-Induced Endothelial Cellular Senescence
  15. 2495
    “…This study aimed to determine the effect of ginger in the prevention of cellular senescence and promotion of muscle regeneration. METHODS: Myoblast cells were cultured into young and senescent state before treated with different concentrations of ginger standardised extracts containing different concentrations of 6-gingerol and 6-shogaol. …”
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    Zingiber Officinale Roscoe Prevents Cellular Senescence of Myoblasts in Culture and Promotes Muscle Regeneration
  16. 2496
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    Targeting T-cell senescence and cytokine storm with rapamycin to prevent severe progression in COVID-19
  17. 2497
    “…Cellular senescence, induced by genotoxic or replication stress, is accompanied by defects in nuclear morphology and nuclear membrane-heterochromatin disruption. …”
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    Spatiotemporal Mislocalization of Nuclear Membrane-Associated Proteins in γ-Irradiation-Induced Senescent Cells
  18. 2498
    “…Senotherapy targeting for senescent cells is designed to attenuate age-related dysfunction. …”
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    The CD153 vaccine is a senotherapeutic option for preventing the accumulation of senescent T cells in mice
  19. 2499
    “…These findings suggest that E2 precipitates a form of mitochondrial damage that leads to cell senescence and autophagy in breast cancer cells.…”
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    Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells
  20. 2500
    “…In the meantime, Illumina RNA-Seq technology was used to evaluate the effect of TA treatment on strawberry fruit senescence. The results showed that 9338 differentially expressed genes (DEGs) were obtained, including 4520 up-regulated DEGs and 4818 down-regulated DEGs. …”
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    Triacontanol Promotes the Fruit Development and Retards Fruit Senescence in Strawberry: A Transcriptome Analysis
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