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  1. 2601
    “…We have employed a stable senescence bypass assay in conditionally immortalised human breast fibroblasts (CL3(EcoR)) to investigate the role of the DREAM complex and its associated components in senescence. …”
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    Simultaneous expression of MMB-FOXM1 complex components enables efficient bypass of senescence
  2. 2602
    “…BACKGROUND: Senescence represents the last stage of flower development. …”
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    Phosphoproteome analysis reveals the involvement of protein dephosphorylation in ethylene-induced corolla senescence in petunia
  3. 2603
    “…Moreover, markers of exaggerated cellular senescence have been proven to accumulate in obese individuals. …”
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    The Interplay of Vitamin D Deficiency and Cellular Senescence in The Pathogenesis of Obesity-Related Co-Morbidities
  4. 2604
    “…Both are also associated with cellular senescence. As OSA patients present with higher prevalence of age-related disorders, such as atrial hypertension or diabetes mellitus type 2, a relationship between OSA and accelerated aging is observable. …”
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    Obstructive Sleep Apnea as an Acceleration Trigger of Cellular Senescence Processes through Telomere Shortening
  5. 2605
    “…AP20187-mediated elimination of p16-dependent senescent cells prevented physiologic, cellular and molecular responses to angiotensin II and provides mechanistic evidence of cellular senescence as a driver of angiotensin II effects.…”
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    Low Dose Chronic Angiotensin II Induces Selective Senescence of Kidney Endothelial Cells
  6. 2606
    “…Our review discusses the aging immune system and highlights that senescence and aging together, play a central role in COVID-19 pathogenesis. …”
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    Role of Senescence and Aging in SARS-CoV-2 Infection and COVID-19 Disease
  7. 2607
    “…We also demonstrated that NO could delay fruit senescence mainly by stimulating antioxidant enzymes, while 1-MCP overly outperformed NO in the treatment of ‘Xiahui-8′ peach in slowing down respiration rate, inhibiting ethylene production, maintaining high firmness and reducing ROS content. …”
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    Synergy of Nitric Oxide and 1-Methylcyclopropene Treatment in Prolong Ripening and Senescence of Peach Fruit
  8. 2608
    “…For example, cellular senescence is an intrinsic aging process that has been recently associated with microbial imbalance. …”
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    Microbiome and Human Aging: Probiotic and Prebiotic Potentials in Longevity, Skin Health and Cellular Senescence
  9. 2609
    “…Since oxidative stress is a major contributing factor to cellular autophagy and senescence, our present investigation determined the impacts of carbofuran‐induced oxidative stress on cellular autophagy and senescence. …”
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    Carbofuran affects cellular autophagy and developmental senescence through the impairment of Nrf2 signalling
  10. 2610
    “…BACKGROUND: Cellular senescence is a complex stress response that impacts cellular function and organismal health. …”
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    The landscape of human tissue and cell type specific expression and co-regulation of senescence genes
  11. 2611
    “…Further research revealed that loss of CMTM6 triggered aberrant activation of DNA damage response, resulting in micronucleus formation and G2/M checkpoint arrest, finally leading to cellular senescence with robust upregulation of numerous chemokines and cytokines. …”
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    Loss of CMTM6 promotes DNA damage-induced cellular senescence and antitumor immunity
  12. 2612
    “…Patient-derived fibroblasts showed nuclear shape abnormalities and premature senescence features, which are two typical cellular phenotypes associated with laminopathies. …”
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    A Rare Mutation in LMNB2 Associated with Lipodystrophy Drives Premature Cell Senescence
  13. 2613
    “…Aging and senescence impact CD4 T helper cell (Th) subset differentiation during influenza infection. …”
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    Senescence‐induced changes in CD4 T cell differentiation can be alleviated by treatment with senolytics
  14. 2614
    “…We sought to determine the factors contributing to the composition of communities in temperate forest substrates, with culture-independent amplicon sequencing of fungal communities of pre-senescent leaf surfaces, internal tissues, leaf litter, underlying humus soil of co-occurring red maple (Acer rubrum) and shagbark hickory (Carya ovata). …”
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    Maple and hickory leaf litter fungal communities reflect pre-senescent leaf communities
  15. 2615
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    Fisetin as a Senotherapeutic Agent: Biopharmaceutical Properties and Crosstalk between Cell Senescence and Neuroprotection
  16. 2616
    “…Exposure to certain environmental toxins has been shown to be associated with cellular senescence mainly through induction of oxidative stress and impact on cellular systems. …”
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    Impact of Acrylamide on Cellular Senescence Response and Cell Cycle Distribution via an In-vitro Study
  17. 2617
    “…Thus, GSK3β appears to play a key role in podocyte senescence by modulating senescence signaling and may be an actionable senostatic target to delay kidney aging.…”
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    Age-related GSK3β overexpression drives podocyte senescence and glomerular aging
  18. 2618
    “…From the previous studies, oxidative stress has been notified as a positive inducement of IDD, which causes DNA damage and accelerates cell senescence. Polyamine oxidase (PAOX), a member of the observed 1057 DEGs, is involved in polyamine metabolism and influences the oxidative balance in cells. …”
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    Rebalance of the Polyamine Metabolism Suppresses Oxidative Stress and Delays Senescence in Nucleus Pulposus Cells
  19. 2619
    “…We show that the fibrotic program is promoted by senescent macrophages. These macrophages were enriched in the fibrotic stroma and exhibit a distinct expression profile. …”
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    Obesity-induced senescent macrophages activate a fibrotic transcriptional program in adipocyte progenitors
  20. 2620
    por Lee, Hyun Seung, Park, Heung-Woo
    Publicado 2021
    “…The role of cellular senescence in the development of asthma is not well known. …”
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    Role of mTOR in the Development of Asthma in Mice With Cigarette Smoke-Induced Cellular Senescence
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