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Agronomía
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2621por Lei, Jinghui, Jiang, Xiaoyu, Li, Wei, Ren, Jie, Wang, Datao, Ji, Zhejun, Wu, Zeming, Cheng, Fang, Cai, Yusheng, Yu, Zheng-Rong, Belmonte, Juan Carlos Izpisua, Li, Chunyi, Liu, Guang-Hui, Zhang, Weiqi, Qu, Jing, Wang, SiEnlace del recurso
Publicado 2021
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2622“…The presence of specific cytokines in the tumor microenvironment has been shown to induce senescence in tumor cells. Subsequently, tumor cells acquire a senescence-associated secretory phenotype that strongly modulates anti-tumor responses. …”
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2623por Tedeschi, Valentina, Paldino, Giorgia, Kunkl, Martina, Paroli, Marino, Sorrentino, Rosa, Tuosto, Loretta, Fiorillo, Maria Teresa“…Moreover, the persistent stimulation by several antigens throughout life favors the switching of CD8(+) T cells towards a senescent phenotype contributing to a low-grade inflammation that is a major component of several ageing-related diseases. …”
Publicado 2022
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2624por Bresson, Justine, Doll, Jasmin, Vasseur, François, Stahl, Mark, von Roepenack-Lahaye, Edda, Kilian, Joachim, Stadelhofer, Bettina, Kremer, James M., Kolb, Dagmar, Wenkel, Stephan, Zentgraf, Ulrike“…The recent finding of the genetic interaction of WRKY53, a key senescence-related gene with REVOLUTA, a master regulator of early leaf patterning, raises the question of how early and late developmental events are connected. …”
Publicado 2022
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2625por Zhang, Zhenlei, Huang, Yizhen, Xu, Nizhen, Wang, Jianle, Yao, Teng, Xu, Yining, Qiao, Di, Gao, Jun, Shen, Shuying, Ma, Jianjun“…Polo-like kinase 1 (PLK1) plays numerous roles in the cell cycle, including in cell proliferation and senescence. To investigate the involvement of PLK1 in IVDD, we used patient tissues and an animal model of IVDD. …”
Publicado 2022
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2626“…Several processes during leaf senescence require coordinated regulation by senescence regulatory genes. …”
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2627por Liang, Chuqian, Ke, Qiong, Liu, Zunpeng, Ren, Jie, Zhang, Weiqi, Hu, Jianli, Wang, Zehua, Chen, Hong, Xia, Kai, Lai, Xingqiang, Wang, Qiaoran, Yang, Kuan, Li, Wei, Wu, Zeming, Wang, Chao, Yan, Haoteng, Jiang, Xiaoyu, Ji, Zhejun, Ma, Miyang, Long, Xiao, Wang, Si, Wang, Huating, Sun, Hao, Belmonte, Juan Carlos Izpisua, Qu, Jing, Xiang, Andy Peng, Liu, Guang-Hui“…Unexpectedly, this phenotype was mainly attributed to a transcription-independent role of BMAL1 in stabilizing heterochromatin and thus preventing activation of the LINE1-cGAS-STING pathway. In senescent primate MPCs, we observed decreased capacity of BMAL1 to bind to LINE1 and synergistic activation of LINE1 expression. …”
Publicado 2022
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2628“…Although the involvement of cellular senescence, a critical component of aging, was suggested in studies of DM1 patient-derived cells, the detailed mechanism of cellular senescence caused by CUG(exp) RNA remains unelucidated. …”
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2629por Suda, Masayoshi, Shimizu, Ippei, Katsuumi, Goro, Hsiao, Chieh Lun, Yoshida, Yohko, Matsumoto, Naomi, Yoshida, Yutaka, Katayama, Akihiro, Wada, Jun, Seki, Masahide, Suzuki, Yutaka, Okuda, Shujiro, Ozaki, Kazuyuki, Nakanishi-Matsui, Mayumi, Minamino, Tohru“…Accumulation of senescent cells in various tissues has been reported to have a pathological role in age-associated diseases. …”
Publicado 2022
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2630“…Leaf senescence is a developmentally programmed cell death process that is influenced by a variety of endogenous signals and environmental factors. …”
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2631“…As anticipated, markers of cellular senescence were elevated in old isochronically-paired mice relative to young controls. …”
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2632por DeSalvio, Aaron J., Adak, Alper, Murray, Seth C., Wilde, Scott C., Isakeit, Thomas“…Current methods in measuring maize (Zea mays L.) southern rust (Puccinia polyspora Underw.) and subsequent crop senescence require expert observation and are resource-intensive and prone to subjectivity. …”
Publicado 2022
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2633“…GSEA indicated that the RAGE‐related differential genes were mainly enriched in senescence‐related pathways. Besides, the RAGE expression was significantly associated with senescence‐related genes. …”
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2634“…In forage crops, age-dependent and stress-induced senescence reduces forage yield and quality. Therefore, delaying leaf senescence may be a way to improve forage yield and quality as well as plant resilience to stresses. …”
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2635por Pedroza-Diaz, Johanna, Arroyave-Ospina, Johanna C., Serna Salas, Sandra, Moshage, Han“…These conditions lead to the activation of different cellular response mechanisms, including senescence. Cellular senescence constitutes an important response to injury in the liver. …”
Publicado 2022
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2636por Nir, Dana, Ribarski-Chorev, Ivana, Shimoni, Chen, Strauss, Carmit, Frank, Jan, Schlesinger, Sharon“…We conclude that while elevated temperatures directly cause mitochondrial damage, senescence is induced by elevated ROS levels. We suggest that heat shock alters cell and tissue homeostasis by several independent mechanisms; however, reducing tissue senescence will reduce damage and provide a pathway to overcome physiological challenges in animals.…”
Publicado 2022
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2637por Wang, Fanhua, Sun, Zhibin, Zhu, Min, Zhang, Qikun, Sun, Yufei, Sun, Wei, Wu, Chunxia, Li, Tongtong, Zhao, Yiwu, Ma, Changle, Zhang, Hui, Zhao, Yanxiu, Wang, Zenglan“…The SD ecotype has dark green leaves, short and flat leaves, and more conspicuous taproots, and the XJ ecotype had greater biomass and showed clear signs of senescence or leaf shedding with age. After 2-DE separation and ESI-MS/MS identification, between 25 and 28 differentially expressed protein spots were identified in shoots and roots, respectively. …”
Publicado 2022
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2638por Ji, Xiaotong, Wang, Meiling, Xu, Zhuangzhuang, Wang, Kai, Sun, Daoyang, Niu, Lixin“…It is well established that endogenous hormones regulate the senescence process, but their molecular mechanism in flower senescence remains unclear. …”
Publicado 2022
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2639por Rhinn, Muriel, Zapata-Bodalo, Irene, Klein, Annabelle, Plassat, Jean-Luc, Knauer-Meyer, Tania, Keyes, William M.“…Together, these findings demonstrate that misregulated senescence in NE cells can contribute to developmental defects.…”
Publicado 2022
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2640por Maschler, Julia, Keller, Jenna, Bialic-Murphy, Lalasia, Zohner, Constantin M., Crowther, Thomas W.“…According to the carbon sink limitation hypothesis, senescence is regulated by the interplay between plant carbon source and sink dynamics, so that senescence occurs later upon low carbon inputs (source) and earlier upon low carbon demand (sink). …”
Publicado 2022
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