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  1. 3821
    “…The net N mineralization rate was higher than control soils by 120% for the senesced litter treatments and 420% for the green litter treatments. …”
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    Nitrogen and Carbon Mineralization from Green and Senesced Leaf Litter Differ between Cycad and Angiosperm Trees
  2. 3822
    “…BACKGROUND: This study aimed to explore the clinical significance of cellular senescence in uterine corpus endometrial carcinoma (UCEC). …”
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    A prognostic model and immune regulation analysis of uterine corpus endometrial carcinoma based on cellular senescence
  3. 3823
    “…BACKGROUND: Accumulation of myofibroblasts is critical to fibrogenesis in idiopathic pulmonary fibrosis (IPF). Senescence and insufficient mitophagy in fibroblasts contribute to their differentiation into myofibroblasts, thereby promoting the development of lung fibrosis. …”
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    Bone morphogenetic protein 4 inhibits pulmonary fibrosis by modulating cellular senescence and mitophagy in lung fibroblasts
  4. 3824
    “…INTRODUCTION: Cellular senescence is a feature of aging implicated in the pathophysiology of diabetes mellitus (DM). …”
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    Circulating differentiated and senescent lymphocyte subsets and incident diabetes risk in older adults: The Cardiovascular Health Study
  5. 3825
    “…However, the accumulation of senescent cells can lead to the progression of various senescence-related disorders. …”
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    β-Galactosidase-Activatable Nile Blue-Based NIR Senoprobe for the Real-Time Detection of Cellular Senescence
  6. 3826
    “…These findings provided the experimental and bioinformatic evidence for a better understanding on the epigenetic factor of miRNAs in association with cellular senescence and spontaneous immortalization process in avian cells.…”
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    Small RNA deep sequencing revealed microRNAs’ involvement in modulating cellular senescence and immortalization state
  7. 3827
    por Takaya, Kento, Asou, Toru, Kishi, Kazuo
    Publicado 2022
    “…Cellular senescence is characterized by cell cycle arrest and the senescence-associated secretory phenotype (SASP) and can be triggered by a variety of stimuli, including deoxyribonucleic acid (DNA) damage, oxidative stress, and telomere exhaustion. …”
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    Cathepsin F is a potential marker for senescent human skin fibroblasts and keratinocytes associated with skin aging
  8. 3828
    “…Cellular senescence-related prognostic genes were identified by WGCNA, COX, and lasso regression analysis, and a cellular senescence-related risk score (CSRS) was calculated. …”
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    Prognostic model construction and validation of esophageal cancer cellular senescence-related genes and correlation with immune infiltration
  9. 3829
    “…They also expand our understanding of the mechanisms leading to senescence and suggest that cytoskeletal dysfunction is an underlying factor in biological aging.…”
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    Genomic instability caused by Arp2/3 complex inactivation results in micronucleus biogenesis and cellular senescence
  10. 3830
    “…The differences in the body compositions were calculated from their MRI images, and the pathological changes in their gastrocnemius muscle were revealed using the H&E staining. Furthermore, the senescence of skeletal muscle cells was evaluated by measuring the expression levels of senescence-related proteins by the western blotting. …”
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    5-Hydroxymethylfurfural induces mice frailty through cell senescence-associated sarcopenia caused by chronic inflammation
  11. 3831
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    Corrigendum: Declined adipogenic potential of senescent MSCs due to shift in insulin signaling and altered exosome cargo
  12. 3832
    “…The process of oncogene-induced senescence (OIS) and the conversion between OIS and malignant transformation during carcinogenesis is poorly understood. …”
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    ATOH8 binds SMAD3 to induce cellular senescence and prevent Ras-driven malignant transformation
  13. 3833
    “…Increased content of senescent cells in the brain, such as glial cells, has been reported to impact cognition both in animal models and human tissue during normal aging and in the context of neurodegenerative disease. …”
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    Age-Associated Upregulation of Glutamate Transporters and Glutamine Synthetase in Senescent Astrocytes In Vitro and in the Mouse and Human Hippocampus
  14. 3834
    “…Cellular senescence plays important roles in age-related diseases, including musculoskeletal disorders. …”
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    Molecular signatures distinguish senescent cells from inflammatory cells in aged mouse callus stromal cells
  15. 3835
    “…In recent studies, senescence has shown an essential role in tumorigenesis and tumor development, yet the extensive effects of senescence in PCa have not been systematically investigated. …”
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    Identification of a novel senescence-associated signature to predict biochemical recurrence and immune microenvironment for prostate cancer
  16. 3836
    “…In addition, transcriptome sequencing results reveal the regulatory effect of CBX4 on the cell cycle, and further western blot analysis and senescence-associated β-galactosidase staining assay indicate that CBX4 overexpression alleviates cell senescence in the presence of TNF-α. …”
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    Chromobox homolog 4 overexpression inhibits TNF-α-induced matrix catabolism and senescence by suppressing activation of NF-κB signaling pathway in nucleus pulposus cells: CBX4 overexpression inhibits TNF-α-induced matrix catabolism and senescence
  17. 3837
    “…BACKGROUND: Osteoarthritis (OA) is the most common degenerative disease in joints among elderly patients. Senescence is deeply involved in the pathogenesis of osteoarthritis. …”
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    Metformin regulates chondrocyte senescence and proliferation through microRNA-34a/SIRT1 pathway in osteoarthritis
  18. 3838
    “…The contribution of cellular senescence to the behavioral changes observed in the elderly remains elusive. …”
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    Protein phosphatase 2A activators reverse age‐related behavioral changes by targeting neural cell senescence
  19. 3839
    “…RESULTS: The results demonstrated that IR reduced murine ovarian reserves, and high doses of insulin caused granulosa cells to senesce. There was a considerable improvement in HFD-induced IR status in the metformin (Met) and GNC treatment groups. …”
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    The Gengnianchun recipe attenuates insulin resistance-induced diminished ovarian reserve through inhibiting the senescence of granulosa cells
  20. 3840
    “…We found that levels of integrin β3 and β-galactosidase (β-gal), two markers of cellular senescence, increased with age in the colonic tissue of mice with AD. …”
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    Integrin β3-Mediated Cell Senescence Associates with Gut Inflammation and Intestinal Degeneration in Models of Alzheimer’s Disease
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