Mostrando 381 - 400 Resultados de 16,559 Para Buscar '"senescal"', tiempo de consulta: 0.38s Limitar resultados
  1. 381
    “…Senescence in biofuel grasses is a critical issue because early senescence decreases potential biomass production by limiting aerial growth and development. 2-Dimensional, differential in-gel electrophoresis (2D-DIGE) followed by mass spectrometry of selected protein spots was used to evaluate differences between leaf proteomes of early (ES)- and late- senescing (LS) genotypes of Prairie cordgrass (ES/LS PCG) and switchgrass (ES/LS SG), just before and after senescence was initiated. …”
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  2. 382
    “…OBJECTIVE: To investigate the possible occurrence of early thymic failure and premature senescence of naïve and memory T-cells in patients with axial spondyloarthritis (aSpA). …”
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  3. 383
    por Yamada, Yusuke, Umehara, Mikihisa
    Publicado 2015
    “…Leaf senescence is a complicated developmental process that involves degenerative changes and nutrient recycling. …”
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  4. 384
    “…Testosterone, but not 17β‐estradiol, counteracted doxorubicin‐elicited senescence. Downregulation of telomere binding factor 2, which has been pinpointed previously as being pivotal to doxorubicin‐induced senescence, was also prevented by testosterone, as were p53 phosphorylation and accumulation. …”
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  5. 385
    por Lowe, Donna, Horvath, Steve, Raj, Kenneth
    Publicado 2016
    “…A confounding aspect of biological ageing is the nature and role of senescent cells. It is unclear whether the three major types of cellular senescence, namely replicative senescence, oncogene-induced senescence and DNA damage-induced senescence are descriptions of the same phenomenon instigated by different sources, or if each of these is distinct, and how they are associated with ageing. …”
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  6. 386
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  8. 388
    “…Cell senescence is associated with the secretion of many factors, the so-called “senescence-associated secretory phenotype”, which may alter tissue microenvironment, stimulating the organism to clean up senescent cells and replace them with newly divided ones. …”
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  9. 389
    “…SA-β-gal staining indicated that DXM increased cell senescence. Notably, DXM-induced cell senescence was exacerbated by the autophagic inhibitor 3-MA. …”
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  10. 390
  11. 391
    “…Induction of replicative senescence in cells was validated by positive senescence-associated β-galactosidase staining. …”
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  12. 392
    “…While many theories exist to explain the aging process, the production of reactive oxygen species (ROS) provides a signaling link between engagement of cellular senescence and several age-associated pathologies. Cellular senescence has evolved to restrict tumor progression but the accompanying senescence-associated secretory phenotype (SASP) promotes pathogenic pathways. …”
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  13. 393
    por Sobieszczuk-Nowicka, E.
    Publicado 2016
    “…Leaf senescence is a terminal step in plant growth and development. …”
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  14. 394
    “…Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by interstitial remodelling, leading to compromised lung function. Cellular senescence markers are detectable within IPF lung tissue and senescent cell deletion rejuvenates pulmonary health in aged mice. …”
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  15. 395
    por Ko, Aram, Han, Su Yeon, Song, Jaewhan
    Publicado 2016
    “…ARF is a key regulator of cellular senescence, an irreversible cell growth arrest that suppresses tumor cell growth. …”
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  16. 396
    “…Cellular senescence can be described as a complex stress response that leads to irreversible cell cycle arrest. …”
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  17. 397
    “…Cellular senescence is defined as an irreversible growth arrest with the acquisition of a distinctive secretome. …”
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  18. 398
    “…Conclusion: Aging from middle age to senescence increases the echocardiographic indexes of LVMI, LVPW thickness, FS and LAD. …”
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  19. 399
    por Demaria, Marco
    Publicado 2017
    “…Many genotoxic chemotherapies have debilitating side effects and induce cellular senescence in normal tissues. Senescent cells acquire a pro-inflammatory phenotype which contributes to local and systemic inflammation. …”
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  20. 400
    “…Senescence represents a mechanism to avoid undesired cell proliferation that plays a role in tumor suppression, wound healing and embryonic development. …”
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