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Mostrando 401 - 420 Resultados de 16,559 Para Buscar '"senescal"', tiempo de consulta: 0.44s Limitar resultados
  1. 401
    “…Senescent cells are present in premalignant lesions and sites of tissue damage and accumulate in tissues with age. …”
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    Quantitative identification of senescent cells in aging and disease
  2. 402
    “…Cell senescence is increasingly recognized as a major contributor to the loss of health and fitness associated with aging. …”
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    Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
  3. 403
    por Park, Sang Chul
    Publicado 2017
    “…For the same reason, varying apoptotic stress factors cannot stimulate the apoptotic pathway in senescent cells. Thus, the operation of a functional nuclear barrier in an aging-dependent manner has been investigated. …”
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    Survive or thrive: tradeoff strategy for cellular senescence
  4. 404
    por Deschênes, Mathieu, Chabot, Benoit
    Publicado 2017
    “…Here we review recent progress documenting how defects in the machinery that performs intron removal and controls splice site selection contribute to cellular senescence and organismal aging. We discuss the functional association linking p53, IGF‐1, SIRT1, and ING‐1 splice variants with senescence and aging, and review a selection of splicing defects occurring in accelerated aging (progeria), vascular aging, and Alzheimer's disease. …”
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    The emerging role of alternative splicing in senescence and aging
  5. 405
    “…Senescence affect different traits of plants, such as the ripening of fruit, number, quality and timing of seed maturation. …”
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    The Role of the S40 Gene Family in Leaf Senescence
  6. 406
    por McHugh, Domhnall, Gil, Jesús
    Publicado 2018
    “…However, senescence has also been implicated as a major cause of age-related disease. …”
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    Senescence and aging: Causes, consequences, and therapeutic avenues
  7. 407
    “…The cytoplasmic chromatin-cGAS-STING pathway promotes the senescence-associated secretory phenotype (SASP) in primary human cells and in mice. …”
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    Cytoplasmic chromatin triggers inflammation in senescence and cancer
  8. 408
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    Cellular Senescence and Inflammaging in Age-Related Diseases
  9. 409
    “…Although senescence has historically been considered a protective mechanism against tumourigenesis, the activities of senescent cells are increasingly being associated with age-related diseases, including cancer. …”
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    Paracrine roles of cellular senescence in promoting tumourigenesis
  10. 410
    “…The senescence-associated secretory phenotype (SASP) is a major trait of senescent cells, but the molecular regulators of SASP factor secretion are poorly understood. …”
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    SCAMP4 enhances the senescent cell secretome
  11. 411
    “…It indicated that morin was effective in delaying banana senescence.…”
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    Morin as a Preservative for Delaying Senescence of Banana
  12. 412
    “…One of the hallmarks of aging is cellular senescence. The elimination of senescent cells with senolytics has very recently been shown to delay age-related dysfunction in animal models for other neurological diseases. …”
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    Targeting senescence to delay progression of multiple sclerosis
  13. 413
    “…Cytokinins modulate a number of important developmental processes, including the last phase of leaf development, known as senescence, which is associated with chlorophyll breakdown, photosynthetic apparatus disintegration and oxidative damage. …”
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    Role of Cytokinins in Senescence, Antioxidant Defence and Photosynthesis
  14. 414
    “…To date, dozens of stress‐induced cellular senescence phenotypes have been reported. These cellular senescence states may differ substantially from each other, as well as from replicative senescence through the presence of specific senescence features. …”
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    Small molecule compounds that induce cellular senescence
  15. 415
    “…Cellular senescence is a state of permanent cell cycle arrest activated in response to damaging stimuli. …”
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    Identification of stable senescence‐associated reference genes
  16. 416
    “…Senescent cells that accumulate in multiple tissues with age are thought to increase pathological phenotypes. …”
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    GRSF1 is an age-related regulator of senescence
  17. 417
    por Wagner, Wolfgang
    Publicado 2019
    “…Replicative senescence of cells in vitro is often considered as counterpart for aging of the organism in vivo. …”
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    The Link Between Epigenetic Clocks for Aging and Senescence
  18. 418
    por Mastri, Michalis, Ebos, John M. L.
    Publicado 2019
    “…Cancer treatments can induce a form of senescence that halts cellular division while allowing continued secretion of tumor-promoting proteins. …”
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    Tumor growth fueled by spurious senescence phenotypes
  19. 419
    por Puvvula, Pavan Kumar
    Publicado 2019
    “…This review focuses on the current findings of the lncRNAs and their dysregulated signaling pathways in senescence. Different functional mechanisms of lncRNAs and their downstream signaling pathways are integrated to provide a bird’s-eye view of lncRNA networks in senescence. …”
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    LncRNAs Regulatory Networks in Cellular Senescence
  20. 420
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    The STATus of STAT3 in Lung Cell Senescence?
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