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  1. 4241
    “…Patients with ESRD have both immune senescence and chronic inflammation that are resumed in the so-called inflammaging syndrome. …”
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    End-Stage Renal Disease-Related Accelerated Immune Senescence: Is Rejuvenation of the Immune System a Therapeutic Goal?
  2. 4242
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    Correction: Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway
  3. 4243
    “…Further research revealed senescence and apoptosis of follicular granulosa cells (GCs), accompanied by arrested follicle development and aberrant estradiol and anti‐Mullerian hormone levels. …”
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    Persistent follicular granulosa cell senescence and apoptosis induced by methotrexate leading to oocyte dysfunction and aberrant embryo development
  4. 4244
    “…Low dose radiation did not induce apoptosis, but induced senescence in irradiated cells. We next examined the expression of immediately early genes including c-Myc and K-Ras. …”
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    Involvement of c-Myc in low dose radiation-induced senescence enhanced migration and invasion of unirradiated cancer cells
  5. 4245
    “…Senescence is an important trait in maize (Zea mais L.), a key crop that provides nutrition values and a renewable source of bioenergy worldwide. …”
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    Precision Mapping of a Maize MAGIC Population Identified a Candidate Gene for the Senescence-Associated Physiological Traits
  6. 4246
    “…Targeting stress-induced senescence of ASCs with metformin may improve age-related adipose tissue dysfunction.…”
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    Metformin alleviates stress-induced cellular senescence of aging human adipose stromal cells and the ensuing adipocyte dysfunction
  7. 4247
    “…BACKGROUND: Senescent cells accumulate in tissues over time as part of the natural ageing process and the removal of senescent cells has shown promise for alleviating many different age-related diseases in mice. …”
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    Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells
  8. 4248
    “…Taken together, our data indicate that MDV-infected bursal B-cells show hallmarks of a senescence-like phenotype, leading to a prolonged B-cell survival. …”
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    Marek’s disease virus prolongs survival of primary chicken B-cells by inducing a senescence-like phenotype
  9. 4249
    “…Thus, clemastine exhibits therapeutic potential in AD via preventing senescence of OPCs.…”
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    Clemastine Ameliorates Myelin Deficits via Preventing Senescence of Oligodendrocytes Precursor Cells in Alzheimer’s Disease Model Mouse
  10. 4250
    “…BACKGROUND: Most common terrestrial animal clades exhibit senescence, suggesting strong adaptive value of this trait. …”
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    Senescence as a trade-off between successful land colonisation and longevity: critical review and analysis of a hypothesis
  11. 4251
    “…Rose plants are one of the most important horticultural crops, whose commercial value mainly depends on long-distance transportation, and wounding and ethylene are the main factors leading to their quality decline and accelerated senescence in the process. However, underlying molecular mechanisms of crosstalk between wounding and ethylene in the regulation of flower senescence remain poorly understood. …”
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    RhWRKY33 Positively Regulates Onset of Floral Senescence by Responding to Wounding- and Ethylene-Signaling in Rose Plants
  12. 4252
    “…LC-MS/MS analysis revealed the formation of non-heme iron-histone complexes and altered expression of histone modifications associated with DNA repair and cellular senescence. In line with this observation, EPIC BeadChip measurements of significant DNA methylation changes in ferroptotic myeloma cells demonstrated an enrichment of CpG probes located in genes associated with cell cycle progression and senescence, such as Nuclear Receptor Subfamily 4 Group A member 2 (NR4A2). …”
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    Ferroptosis Induction in Multiple Myeloma Cells Triggers DNA Methylation and Histone Modification Changes Associated with Cellular Senescence
  13. 4253
    “…Monthly sampling of the Sargassum biofilm links the temporal taxonomic and putative functional metabolic microbiome changes, examined using 16S rRNA gene amplicon and metagenomic sequencing, to the pronounced growth-reproduction-senescence cycle of the host. Overall, the macroalgal biofilm was dominated by the heterotrophic phyla Firmicutes (35% ± 5.9% SD) and Bacteroidetes (12% ± 0.6% SD); their relative abundance ratio shifted significantly along the annual growth-reproduction-senescence cycle of Sargassum. …”
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    Microbial Surface Biofilm Responds to the Growth-Reproduction-Senescence Cycle of the Dominant Coral Reef Macroalgae Sargassum spp.
  14. 4254
    “…Cells are the basic unit of organs and body tissues, and cellular senescence plays an important role in the aging process. …”
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    Exposure to 10 Hz Pulsed Magnetic Fields Do Not Induce Cellular Senescence in Human Fetal Lung Fibroblasts
  15. 4255
    “…The genetics of senescence regulation are largely unknown, with senescence variation often correlated with phenological traits. …”
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    Delaying or delivering: identification of novel NAM-1 alleles that delay senescence to extend wheat grain fill duration
  16. 4256
    “…Rat primary cortical astrocytes were seeded in transwell inserts and induced to premature senescence with hydrogen peroxide [stress-induced premature senescence (SIPS)]. …”
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    Senescence in Primary Rat Astrocytes Induces Loss of the Mitochondrial Membrane Potential and Alters Mitochondrial Dynamics in Cortical Neurons
  17. 4257
    “…Cellular senescence signal p16INK4a has been identified as a biomarker of aging that accumulates with chronological age across several tissues in mice and humans and may be potentially modifiable by interventions. …”
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    Physical Indicators of Aging are Related to Cellular Senescence Signal P16INK4a in Midlife Adults
  18. 4258
    “…In this study, we investigated the role of mulberry polyphenol extract (MPE) in K-Ras-induced senescence of smooth muscle cells. Forced expression of K-Ras enhanced senescence of smooth muscle A7r5 cells as shown by the elevation of β-galactosidase activity. …”
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    Mulberry polyphenol extracts attenuated senescence through inhibition of Ras/ERK via promoting Ras degradation in VSMC
  19. 4259
    “…There were changes of senescence biomarkers including SA-β-gal activity and expression of p16INK4A and p21Waf1/Cip1 in senescent cells. …”
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    nc886, a Non-Coding RNA, Is a New Biomarker and Epigenetic Mediator of Cellular Senescence in Fibroblasts
  20. 4260
    “…In addition, constitutive over-expression of NaNAC29 in A. thaliana could rescue the delayed-senescence phenotype of nap and caused precocious leaf senescence of wild-type Col-0 plants. …”
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    Involvement of NAC transcription factor NaNAC29 in Alternaria alternata resistance and leaf senescence in Nicotiana attenuata
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