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  1. 4301
    “…Furthermore, the knockdown of FOXO1 repressed the decidual senescence induced by siRNA-based PGRMC1 knockdown or AG-205 treatment. …”
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    PGRMC1 Regulates Cellular Senescence via Modulating FOXO1 Expression in Decidualizing Endometrial Stromal Cells
  2. 4302
    “…In response to many stresses, such as oncogene activation or DNA damage, cells can enter cellular senescence, a state of proliferation arrest accompanied by a senescence-associated secretory phenotype (SASP). …”
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    Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca(2+) Levels in Senescent Cells
  3. 4303
    “…Furthermore, the two combinations significantly improved the rat experimental tendinopathy by reducing ultrasound feature scores and histological scores as well as the levels of apoptosis, senescence, and senescence-associated secretory phenotypes (p < 0.05, all). …”
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    Cross-Linked Hyaluronate and Corticosteroid Combination Ameliorate the Rat Experimental Tendinopathy through Anti-Senescent and -Apoptotic Effects
  4. 4304
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    Senescence-Independent Anti-Inflammatory Activity of the Senolytic Drugs Dasatinib, Navitoclax, and Venetoclax in Zebrafish Models of Chronic Inflammation
  5. 4305
    “…ICT treatment could also reduce neuronal apoptosis and senescence and reversed the expression of apoptosis- and senescence-related signaling proteins. …”
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    Therapeutic Effect of Icaritin on Cerebral Ischemia-Reperfusion-Induced Senescence and Apoptosis in an Acute Ischemic Stroke Mouse Model
  6. 4306
    “…Two types of senescent astrocytes’ conditioned medium could impact on neuron apoptosis in direct or indirect ways. (4) Conclusions: Senescent astrocyte might affect neurons directly or indirectly acting on the regulation of normal and pathological brain aging.…”
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    Senescent Phenotype of Astrocytes Leads to Activation of BV2 Microglia and N2a Neuronal Cells Death
  7. 4307
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    Chemical composition and anti-aging effects of standardized herbal chicken essence on D-galactose- induced senescent mice
  8. 4308
    “…Cellular senescence is a plausible mediator of inflammation-related tissue dysfunction. …”
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    Rejuvenation of the aged brain immune cell landscape in mice through p16-positive senescent cell clearance
  9. 4309
    “…Radiotherapy and chemotherapy can arrest cancer cells in a senescence-like state, which can lead to therapy resistance and cancer relapse. mTOR is hyperactivated in senescent cells but the mechanisms remain unclear. …”
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    RagC GTPase regulates mTOR to promote chemoresistance in senescence-like HepG2 cells
  10. 4310
    “…However, it is being progressively realized that immunosenescence may not be the only determinant of immunological aging. The cellular senescence-centric theory of aging proposes a more fundamental and specific role of immune cells in regulating senescent cell (SC) burden in aging tissues that has augmented the notion of senescence immunotherapy. …”
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    Emerging cellular senescence-centric understanding of immunological aging and its potential modulation through dietary bioactive components
  11. 4311
    “…C1 and C2 were identified as the senescence-suppressed and senescence-activated subgroups. …”
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    Identification of cell senescence molecular subtypes in prediction of the prognosis and immunotherapy of hepatitis B virus-related hepatocellular carcinoma
  12. 4312
    “…Expression profiles of genes related to cellular senescence were used to identify molecular subtypes by consensus clustering. …”
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    Identification and Analysis of Senescence-Related Genes in Head and Neck Squamous Cell Carcinoma by a Comprehensive Bioinformatics Approach
  13. 4313
    “…Within the complexity of a tissue, identification and targeting of senescent cells is hampered by their heterogeneity. …”
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    Establishment of In Vitro Models by Stress-Induced Premature Senescence for Characterizing the Stromal Vascular Niche in Human Adipose Tissue
  14. 4314
    “…Background: Cellular senescence plays a complicated and vital role in cancer development because of its divergent effects on tumorigenicity. …”
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    Identification of senescence-associated long non-coding RNAs to predict prognosis and immune microenvironment in patients with hepatocellular carcinoma
  15. 4315
    “…Here, we for the first time explored the effects of (1) autophagy activation by 48 h fasting, (2) inhibition by chloroquine (CQ) treatment, and (3) combined effects of fasting and CQ on the quantitative composition of metabolites in the blood serum of senescent-accelerated OXYS and control Wistar rats at the age of 4 months. …”
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    Quantitative Metabolomic Analysis of Changes in the Rat Blood Serum during Autophagy Modulation: A Focus on Accelerated Senescence
  16. 4316
    “…Age-related and stress-induced cellular senescence accompanied by further active processes represent the key elements of AS pathomechanism. …”
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    Cellular Senescence, Aging and Non-Aging Processes in Calcified Aortic Valve Stenosis: From Bench-Side to Bedside
  17. 4317
    “…Frailty indicators and immune senescence markers were determined at baseline to identify predictors of the immune response. …”
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    Immune Senescence Markers Predict the Cellular Immune Response to BNT162b2 Vaccination in Hemodialysis Patients
  18. 4318
    “…Background: Cellular senescence has recently been considered a new cancer hallmark. …”
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    A novel senescence-related lncRNA signature that predicts prognosis and the tumor microenvironment in patients with lung adenocarcinoma
  19. 4319
    “…Especially carbon starvation induced by dark-incubation causes a dramatic increase in mitophagy within a few hours, further increasing as dark-induced senescence progresses. Natural senescence was also a strong trigger of mitophagy, peaking when leaf yellowing became prominent. …”
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    Carbon starvation, senescence and specific mitochondrial stresses, but not nitrogen starvation and general stresses, are major triggers for mitophagy in Arabidopsis
  20. 4320
    Publicado 2022
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    Correction to: Blockade of integrin signaling reduces chemotherapy-induced premature senescence in collagen cultured bladder cancer cells
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