Materias dentro de su búsqueda.
Materias dentro de su búsqueda.
Agronomía
1
Aspectos moleculares
1
Biología molecular
1
Cultivo de células
1
Cultivo de tejidos
1
Cultivos
1
Cáncer
1
Dieta para enfermos
1
Dietoterapia
1
Ecología
1
Fisiología
1
Fontosíntesis
1
Hábitos y conducta
1
Ingeniería genética
1
Investigaciones
1
Mamíferos
1
Mejoramiento de los cultivos
1
Metodología
1
Nutrición
1
Quirópteros
1
Química vegetal
1
-
4321
-
4322por Liu, Jian-Xiang, Cui, Dao-Lei, Yang, Dan-Lei, Li, Jing-Ya, Yang, Zi-Yue, Su, Jin-Zhou, Ren, Cai-Xia, Niu, You-Ya, Xiang, Ping“…Additionally, both the senescence-associated-β-galactosidase activity and related proinflammatory cytokine IL-1β and IL-6 were elevated, indicating that TCPP exposure caused cellular senescence may be through the p53-dependent DNA damage signal pathway in HaCaT cells. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4323por Yang, Letian, Wang, Bo, Guo, Fan, Huang, Rongshuang, Liang, Yan, Li, Lingzhi, Tao, Sibei, Yin, Ting, Fu, Ping, Ma, Liang“…Notably, FFAR4, as a key determinant, was firstly explored to regulate cellular senescence both in injured kidneys of AKI mice and TECs, which was indicated by senescence-associated β-galactosidase (SA-β-gal) activity, marker protein p53, p21, Lamin B1, phospho-histone H2A.X, phospho-Rb expression, and secretory phenotype IL-6 level. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4324por Ijima, Shogo, Saito, Yuki, Nagaoka, Kentaro, Yamamoto, Sena, Sato, Tsukasa, Miura, Norihiro, Iwamoto, Taiki, Miyajima, Maki, Chikenji, Takako S.“…Furthermore, fisetin treatment in vivo reduced the number of senescent TECs and myofibroblasts, which attenuated kidney fibrosis, reduced senescence-associated secretory phenotype (SASP) expression, and increased TEC proliferation. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4325Senescent cells suppress macrophage-mediated corpse removal via upregulation of the CD47-QPCT/L axispor Schloesser, Daniela, Lindenthal, Laura, Sauer, Julia, Chung, Kyoung-Jin, Chavakis, Triantafyllos, Griesser, Eva, Baskaran, Praveen, Maier-Habelsberger, Ulrike, Fundel-Clemens, Katrin, Schlotthauer, Ines, Watson, Carolin Kirsten, Swee, Lee Kim, Igney, Frederik, Park, John Edward, Huber-Lang, Markus S., Thomas, Matthew-James, El Kasmi, Karim Christian, Murray, Peter J.“…Senescent cell-mediated efferocytosis suppression (SCES) was independent of the senescence-associated secretory phenotype (SASP) but instead required direct contact between macrophages and senescent cells. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4326por Ramini, Deborah, Latini, Silvia, Giuliani, Angelica, Matacchione, Giulia, Sabbatinelli, Jacopo, Mensà, Emanuela, Bacalini, Maria Giulia, Garagnani, Paolo, Rippo, Maria Rita, Bronte, Giuseppe, Bonafè, Massimiliano, Cardelli, Maurizio, Olivieri, Fabiola“…We previously analysed genome-wide DNA methylation of young and replicative senescent human endothelial cells (HUVECs), highlighting increased levels of demethylated sequences in senescent cells. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4327por Zhang, Yi, Tang, Yunhui, Liu, Yang, Wang, Jiayi, Shen, Ye, Sun, Xinyi, Kang, Matthew, Zhao, Min, Chen, Qi“…Placental dysfunction, including senescent changes, is associated with the pathogenesis of missed miscarriage, although the underlying mechanism is unclear. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4328por Zheng, Dan‐Lin, Wu, Qing‐Rui, Zeng, Peng, Li, Sui‐Min, Cai, Yong‐Jiang, Chen, Shu‐Zhen, Luo, Xue‐Shan, Kuang, Su‐Juan, Rao, Fang, Lai, Ying‐Yu, Zhou, Meng‐Yuan, Wu, Fei‐Long, Yang, Hui, Deng, Chun‐Yu“…Here, we aim to clarify the role and mechanism of atrial myocyte senescence in the susceptibility of AF in diabetes. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4329por Liu, Lei, Yue, Xianlin, Sun, Zewei, Hambright, William S., Wei, Jianming, Li, Ying, Matre, Polina, Cui, Yan, Wang, Zhihui, Rodney, George, Huard, Johnny, Robbins, Paul D., Mu, Xiaodong“…FAPs isolated from Z24(−/−) muscle contained about 44% SA‐β‐gal+ senescent cells, in contrast to about 3.5% senescent cells in FAPs isolated from WT muscle (n > =6, P < 0.001). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4330por Li, Juan, Wang, Yang, Luo, Yue, Liu, Yang, Yi, Yong, Li, Jinsong, Pan, Yang, Li, Weiyuxin, You, Wanbang, Hu, Qingyong, Zhao, Zhiqiang, Zhang, Yujun, Cao, Yang, Zhang, Lingqiang, Yuan, Junying, Xiao, Zhi-Xiong Jim“…Non-small cell lung cancers (NSCLC) frequently contain KRAS mutation but retain wild-type TP53. Abundant senescent cells are observed in premalignant but not in malignant tumors derived from the Kras-driven mouse model, suggesting that KRAS oncogenic signaling would have to overcome the intrinsic senescence burden for cancer progression. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4331por Li, Shuwen, Xie, Hong, Zhou, Lingfang, Dong, Di, Liu, Yaling, Jia, Chenyan, Han, Liebao, Chao, Yuehui, Chen, Yinglong“…Here, we reported the isolation and functional analysis of an alfalfa SENESCENCE-ASSOCIATED GENE113 (MsSAG113), which belongs to the PP2C family and mainly plays a role in promoting plant senescence. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4332por Wang, Chunlai, Gao, Bai, Chen, Nannan, Jiao, Peng, Jiang, Zhenzhong, Zhao, Chunli, Ma, Yiyong, Guan, Shuyan, Liu, Siyan“…In addition, the ZmSAG39 overexpression in maize accelerated the senescence of maize leaves under darkness and drought treatments. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4333
-
4334por Zhang, Zizhen, Xue, Meng, Chen, Jingyu, Wang, Zhuo, Ju, Fangyu, Ni, Jiaojiao, Sun, Jiawei, Wu, Haoyue, Zheng, Huimei, Lou, Ziwei, Zhang, Yawen, Yang, Xiaohang, Chen, Shujie, Xi, Yongmei, Wang, Liangjing“…In human CCD-18Co cells, knockdown of METTL14 accelerated cellular senescence, and the overexpression of METTL14 rescued senescent phenotypes. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4335por Hu, Qianying, Zhang, Na, Sui, Tingting, Li, Guanlin, Wang, Zhiyao, Liu, Mingyue, Zhu, Xiaojuan, Huang, Baiqu, Lu, Jun, Li, Zhanjun, Zhang, Yu“…Functional inhibition of miR‐59 alleviated the cellular senescence phenotype of HGPS cells. Treatment with AAV9‐mediated anti‐miR‐59 reduced fibrosis in the quadriceps muscle, heart, and aorta, suppressed epidermal thinning and dermal fat loss, and yielded a 25.5% increase in longevity of Lmna ( G609G/G609G ) mice. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4336por Yu, Yi, Ren, Yuanyuan, Li, Zi, Li, Yang, Li, Yirong, Zhang, Yan, Gui, Runlin, Cui, Yue, Qian, Lu, Xiong, Yuyan“…Autophagy plays a crucial role in the modulation of cellular senescence. Our previous showed that myosin 1b (Myo1b), one family of nonfilamentous class-1 myosin, was reported to be involved in the modulation of human smooth muscle cell senescence. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4337por Giuliani, Angelica, Bacalini, Maria Giulia, Ramini, Deborah, Mensà, Emanuela, Giordani, Chiara, Xumerle, Luciano, Garagnani, Paolo, Olivieri, Fabiola, Procopio, Antonio Domenico, Rippo, Maria Rita, Sabbatinelli, Jacopo“…These cells have a limited number of replications and enter replicative senescence during in vitro expansion. The role of DNA methylation (DNAm) assumes importance in cell function and commitment; however, its exact contribution to BMSC differentiation and replicative senescence is still unclear. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4338“…BACKGROUND: As a cellular process, senescence functions to prevent the proliferation of damaged, old and tumor-like cells, as well as participate in embryonic development, tissue repair, etc. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4339por Wang, Yuan, Sui, Yutong, Niu, Ye, Liu, Dan, Xu, Qi, Liu, Feilin, Zuo, Kuiyang, Liu, Mingsheng, Sun, Wei, Wang, Ziyu, Liu, Zinan, Zou, Fei, Shi, Jiahong, Liu, Xiaomei, Liu, Jinyu“…Stem cell senescence and depletion are major causes of aging and aging-related diseases. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4340por Wang, Dan, Yin, Ling, Chen, Rongyu, Tan, Wanlin, Liang, Luqun, Xiang, Jiayi, Zhang, Huifang, Zhou, Xingcheng, Deng, Huaqing, Guo, Bing, Wang, Yuanyuan“…A recent study has shown that senescence is associated with the course of DKD. In the present study, we explored whether senescent renal tubular cells promote renal tubulointerstitial fibrosis by secreting Sonic hedgehog (Shh) which mediates fibroblast activation and proliferation in DKD. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto