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  1. 4561
    “…Moreover, incubation with pectin favors cellular senescence over apoptosis in HT29 cells.…”
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    Effect of Pectin on the Expression of Proteins Associated with Mitochondrial Biogenesis and Cell Senescence in HT29-Human Colorectal Adenocarcinoma Cells
  2. 4562
    “…This process is characterized amongst others by less naive T-cells and more senescent phenotypes, which have been implicated in the pathogenesis of many age-related diseases. …”
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    Six weeks of strength endurance training decreases circulating senescence-prone T-lymphocytes in cytomegalovirus seropositive but not seronegative older women
  3. 4563
    “…Our in vitro study revealed that IgE induced smooth muscle cell senescence via upregulating lincRNA-p21 against p21 without altering expression of p53. …”
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    IgE Aggravates the Senescence of Smooth Muscle Cells in Abdominal Aortic Aneurysm by Upregulating LincRNA-p21
  4. 4564
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    Corrigendum to “Mitochondrial (Dys) Function in Inflammaging: Do MitomiRs Influence the Energetic, Oxidative, and Inflammatory Status of Senescent Cells?”
  5. 4565
    “…Strikingly, CXCR2 knockout monocytes infused in Pten(pc−/−); Trp53(pc−/−) mice differentiated in tumor necrosis factor alpha (TNF-α)-releasing pro-inflammatory macrophages, leading to senescence and tumor inhibition. Mechanistically, PTEN-deficient tumor cells are vulnerable to TNF-α-induced senescence, because of an increase of TNFR1. …”
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    Re-education of Tumor-Associated Macrophages by CXCR2 Blockade Drives Senescence and Tumor Inhibition in Advanced Prostate Cancer
  6. 4566
    “…Cellular senescence plays both beneficial and detrimental roles in embryonic development and tissue regeneration, while the underlying mechanism remains elusive. …”
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    Hsp90β interacts with MDM2 to suppress p53‐dependent senescence during skeletal muscle regeneration
  7. 4567
    “…Finally, we showed POLR2A mediated cell senescence caused by XAB2 deficiency. Depletion of XAB2 or POLR2A induced cell senescence by up-regulation of p53 and p21, re-expression of POLR2A after XAB2 depletion alleviated cellular senescence. …”
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    XAB2 depletion induces intron retention in POLR2A to impair global transcription and promote cellular senescence
  8. 4568
    “…Here we show that during induction of DNA damage-induced senescence in human non-cancerous cells, PML accumulates at the nucleolar periphery simultaneously with inactivation of RNA polymerase I (RNAP I) and nucleolar segregation. …”
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    Dynamic PML protein nucleolar associations with persistent DNA damage lesions in response to nucleolar stress and senescence-inducing stimuli
  9. 4569
    “…When highly purified iPSC‐EVs were applied in culture to senescent MSCs that have elevated reactive oxygen species (ROS), human iPSC‐EVs reduced cellular ROS levels and alleviated aging phenotypes of senescent MSCs. …”
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    Highly Purified Human Extracellular Vesicles Produced by Stem Cells Alleviate Aging Cellular Phenotypes of Senescent Human Cells
  10. 4570
    “…However, Cx43 may play a more impactful role in protecting MSCs from premature senescence.…”
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    Connexin43 is Dispensable for Early Stage Human Mesenchymal Stem Cell Adipogenic Differentiation But is Protective against Cell Senescence
  11. 4571
    “…The activation of the p53/p21 pathway and the number of senescence-associated β-galactosidase (SA-β-gal)-positive cells were evaluated. …”
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    Activation of the leptin pathway by high expression of the long form of the leptin receptor (Ob-Rb) accelerates chondrocyte senescence in osteoarthritis
  12. 4572
    Publicado 2019
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    20(S)-Ginsenoside Rg3 Promotes Senescence And Apoptosis In Gallbladder Cancer Cells Via The P53 Pathway [Corrigendum]
  13. 4573
    “…Leaf senescence can be delayed by plant hormones such as cytokinin. …”
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    Improved Wheat Growth and Yield by Delayed Leaf Senescence Using Developmentally Regulated Expression of a Cytokinin Biosynthesis Gene
  14. 4574
    por Li, Li, Wang, Xiaoke, Manning, William J.
    Publicado 2019
    “…In conclusion, autumnal senescence of T. americana was accelerated, while the leaf falling duration was extended by elevated [CO(2)]. …”
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    Effects of Elevated CO(2) on Leaf Senescence, Leaf Nitrogen Resorption, and Late-Season Photosynthesis in Tilia americana L.
  15. 4575
    “…BACKGROUND: Leaf senescence is a complex process, controlled by multiple genetic and environmental variables. …”
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    Exploring gene networks in two sunflower lines with contrasting leaf senescence phenotype using a system biology approach
  16. 4576
    “…Moreover, cellular senescence signatures, derived from a meta‐analysis, changed in the same direction as aging in human tissues and in the opposite direction of cancer signatures. …”
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    A human tissue‐specific transcriptomic analysis reveals a complex relationship between aging, cancer, and cellular senescence
  17. 4577
    “…WRKY transcription factors (TFs) play essential roles in the plant response to leaf senescence and abiotic stress. However, the WRKY TFs involved in leaf senescence and stress tolerance in cotton (Gossypium hirsutum L.) are still largely unknown. …”
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    The Cotton GhWRKY91 Transcription Factor Mediates Leaf Senescence and Responses to Drought Stress in Transgenic Arabidopsis thaliana
  18. 4578
    “…Specific treatment for CB2-positive microglia might help ameliorate senescence-related neuroinflammation and the following neurodegeneration.…”
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    Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study
  19. 4579
    “…In the dark induced senescence assay, SGM-3 showed delayed senescence while SGM-1 and SGM-2 showed complete lack of senescence. …”
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    A Novel Stay-Green Mutant of Rice with Delayed Leaf Senescence and Better Harvest Index Confers Drought Tolerance
  20. 4580
    “…SND1 is involved in cellular senescence induced by PIM1. CONCLUSIONS: We investigated the role of PIM1 in oncogene-induced normal cellular senescence. …”
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    The Oncogene PIM1 Contributes to Cellular Senescence by Phosphorylating Staphylococcal Nuclease Domain-Containing Protein 1 (SND1)
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