Mostrando 4,581 - 4,600 Resultados de 16,559 Para Buscar '"senescal"', tiempo de consulta: 0.21s Limitar resultados
  1. 4581
    “…In conclusion, our findings show that NANOG delays HF-MSC senescence by upregulating PBX1 and activating AKT signaling and that a feedback loop likely exists between PBX1 and AKT signaling.…”
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  2. 4582
    “…This is a study on the relationship between the protective effect of ginsenoside Rg1 on senescent neural stem cells and Wnt-β/catenin signaling pathway. …”
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  3. 4583
    “…Methods: We induced cellular and cochlear senescence using hydrogen peroxide (H(2)O(2)) and evaluated the level of senescence through senescence-associated β-galactosidase staining. …”
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  4. 4584
  5. 4585
  6. 4586
    “…Sirtuin 1 (SIRT1) has been shown to protect against mitochondrial dysfunction and other pathological processes, including premature senescence. This study was aimed to investigate whether and how H(2)S attenuates senescence and apoptosis of alveolar epithelial cells via a SIRT1-dependent mechanism. …”
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  7. 4587
    “…Leaf senescence, either as a natural stage of development or as an induced process under stress conditions, incorporates multiple intricate signaling pathways. …”
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  8. 4588
    “…Scn4b) and cellular senescence (e.g. Cdkn2a products) responses. Top striatal weighted edges are enriched in modulators of defective behavior in invertebrate models of HD pathogenesis, validating their relevance to neuronal dysfunction in vivo. …”
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  9. 4589
    “…Spalax fibroblasts undergo replicative senescence (RS) and etoposide‐induced senescence (EIS), evidenced by an increased activity of senescence‐associated beta‐galactosidase (SA‐β‐Gal), growth arrest, and overexpression of p21, p16, and p53 mRNAs. …”
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  10. 4590
  11. 4591
    por Lee, Hyelim, Cha, Hyeonjin, Park, Ju Hyun
    Publicado 2020
    “…In addition, it was revealed that the iPSC-CNEV restored senescence-related alterations of gene expression. Treatment with iPSC-CENVs significantly reduced the activity of senescence-associated-β-galactosidase (SA-β-Gal) in senescent HDFs, as well as suppressing the elevated expression of p53 and p21, key factors involved in cell cycle arrest, apoptosis, and cellular senescence signaling pathways. …”
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  12. 4592
  13. 4593
  14. 4594
    “…Increased injuries were observed by upregulating endothelial apoptosis- and senescence-positive staining, along with caspase-3 activity and down-regulating telomerase activity. …”
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  15. 4595
    “…Male late-onset hypogonadism is an age-related disease, the core mechanism of which is dysfunction of senescent Leydig cells. Recent studies have shown that elimination of senescent cells can restore proper homeostasis to aging tissue. …”
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  16. 4596
    “…To address this issue, we investigated the effect of melatonin on replicative senescence in MSCs. In senescent MSCs (late passage), replicative senescence decreased mitophagy by inhibiting mitofission, resulting in the augmentation of mitochondrial dysfunction. …”
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  17. 4597
    “…Immunosenescence in monocytes has been shown to be associated with several biochemical and functional changes, including development of senescence-associated secretory phenotype (SASP), which may be inhibited by klotho protein. …”
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  18. 4598
  19. 4599
    “…To better understand the molecular control of leaf senescence, we examined transcriptome changes during seasonal leaf senescence in Populus trichocarpa Nisqually-1, the Populus reference genome, growing in its natural habitat. …”
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  20. 4600
    “…The defects observed in the muscle and SAT may occur independent of cellular senescence or alterations in mitochondrial function. …”
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