Mostrando 5,041 - 5,060 Resultados de 16,559 Para Buscar '"senescal"', tiempo de consulta: 0.23s Limitar resultados
  1. 5041
    “…This study aimed to investigate the manner in which aging and pre-existing cognitive dysfunction modified neuroinflammation, synaptic plasticity, and basal synaptic transmission during the acute phase of sepsis using Senescence-Accelerated Mice Prone 8 (SAMP8) and Senescence-Accelerated Resistant Mice 1 (SAMR1). …”
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  2. 5042
    “…Obesity promotes premature aging and dysfunction of white adipose tissue (WAT) through the accumulation of cellular senescence. The senescent cells burden in WAT has been linked to inflammation, insulin-resistance (IR), and type 2 diabetes (T2D). …”
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  3. 5043
    “…Taken together, this work revealed that the CYP71P1 is involved in regulation of both premature senescence and cell death in rice, and its different mutation sites and mutation types could cause different phenotypes in terms of severity.…”
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  4. 5044
  5. 5045
    “…Here we show that genome-wide redistribution of METTL3 and METTL14 transcriptionally drives senescence-associated secretory phenotype (SASP) in a m(6)A-independent manner. …”
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  6. 5046
    “…Gene expression of TLR-1,2,4,6, senescence and senescence-associated secretory phenotype (SASP) markers was evaluated by RT-qPCR in isolated cells. …”
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  7. 5047
    “…In the progression of PH, senescence PASMCs could contribute to PASMC proliferation via increasing the expression of paracrine IL-6 (senescence-associated secretory phenotype). …”
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  8. 5048
    “…Several strategies such as small molecules treatment have been widely studied and used to improve the stem characteristics bypassing the senescence but the exact mechanisms for them to reduce senescence have not been fully studied. …”
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  9. 5049
    “…In this study, markers of DNA damage and senescence were unambiguously and permanently elevated in native T2DM versus non-diabetic (ND)-SMC. …”
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  10. 5050
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  12. 5052
  13. 5053
  14. 5054
    “…The members of the sirtuin family of NAD(+)-dependent enzymes play an anti-senescence role and their activation suggests a promising approach for preventing UV-induced senescence in the treatment of skin aging. …”
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  15. 5055
    “…It remains unknown whether DIPG undergoes senescence following radiation, and furthermore, whether senolytics can be utilised to target senescent DIPG cells. …”
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  16. 5056
  17. 5057
  18. 5058
    “…Then, cell activity, migration, and senescence were measured by Cell Counting Kit-8 assay, transwell assay, and β-galactosidase staining, respectively. …”
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  19. 5059
    “…Aging-associated dermatological pigmentary diseases are associated with accumulation of senescence cells and the disruption of basement membrane due to chronic ultraviolet radiation (UVR) exposure. …”
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  20. 5060
    “…Senescent cells may escape from senescence, contributing to the formation of recurrences or can induce the senescence-associated secretory phenotype (SASP), which may impact therapy success. …”
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