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Mostrando 541 - 560 Resultados de 16,559 Para Buscar '"senescal"', tiempo de consulta: 0.23s Limitar resultados
  1. 541
    “…In the present study, we found osteogenic cells from aged rats all exhibited senescence changes, with the most pronounced senescence changes in osteocytes. …”
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    Low magnitude vibration alleviates age-related bone loss by inhibiting cell senescence of osteogenic cells in naturally senescent rats
  2. 542
    “…Compared with fat tissue from young mice, senescence-associated secretory phenotype (SASP) factors were upregulated in fat tissue from old mice. …”
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    Senescence of donor cells impairs fat graft regeneration by suppressing adipogenesis and increasing expression of senescence-associated secretory phenotype factors
  3. 543
    “…Senescent cells, which arise due to damage-associated signals, are apoptosis-resistant and can express a pro-inflammatory, tissue-destructive senescence-associated secretory phenotype (SASP). …”
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    SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3
  4. 544
    “…Senescence occurs in response to a number of damaging stimuli to limit oncogenic transformation and cancer development. …”
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    Senescence-associated morphological profiles (SAMPs): an image-based phenotypic profiling method for evaluating the inter and intra model heterogeneity of senescence
  5. 545
    “…The identification and validation of differentially expressed genes (DEGs) via RNA-seq and quantitative real-time PCR provided up- and down-regulated senescence markers for each senescence and putative senescence regulators that trigger common senescence pathways. …”
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    Comprehensive transcriptomic analysis of age-, dark-, and salt-induced senescence reveals underlying mechanisms and key regulators of leaf senescence in Zoysia japonica
  6. 546
    “…DNA damage resulting from genotoxic injury can initiate cellular senescence, a state characterized by alterations in cellular metabolism, lysosomal activity, and the secretion of factors collectively known as the senescence-associated secretory phenotype (SASP). …”
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    Meta-analysis of senescent cell secretomes to identify common and specific features of the different senescent phenotypes: a tool for developing new senotherapeutics
  7. 547
    “…Cellular senescence is the permanent arrest of cell cycle, physiologically related to aging and aging-associated diseases. …”
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    Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
  8. 548
    “…Leaf senescence is a finely tuned and genetically programmed degeneration process, which is critical to maximize plant fitness by remobilizing nutrients from senescing leaves to newly developing organs. …”
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    Gene regulatory cascade of senescence-associated NAC transcription factors activated by ETHYLENE-INSENSITIVE2-mediated leaf senescence signalling in Arabidopsis
  9. 549
    “…Both senescence and quiescence are common programs of proliferative arrest that are integral to tissue development and homeostasis. …”
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    Dormant cancer cells: programmed quiescence, senescence, or both?
  10. 550
    “…Cellular senescence is a cell fate that prominently impacts physiological and pathophysiological processes. …”
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    Dynamic modeling of the cellular senescence gene regulatory network
  11. 551
    “…Inhibition of nutrient‐sensing mTORC1 signaling increases exosome release and delays senescence, while constitutive activation of mTORC1 reduces exosome secretion and exacerbates senescence in vitro and in mice. …”
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    Exosome Release Delays Senescence by Disposing of Obsolete Biomolecules
  12. 552
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    Senescence and extracellular vesicles: novel partners in vascular amyloidosis
  13. 553
    “…Although tumor cell senescence may serve as a barrier to tumor proliferation, more studies have shown that stromal cell senescence in the tumor microenvironment contributes to the growth and regulation of tumor cells through senescence-associated secretory phenotypes. …”
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    Senescent Stromal Cells in the Tumor Microenvironment: Victims or Accomplices?
  14. 554
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    Senescent cells enhance ischemic aging in the female heart
  15. 555
    “…We and others have reported that senescence onset is accompanied by genomic instability that is evident by several defects, such as aneuploidy or erroneous mitosis features. …”
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    The establishment of mitotic errors-driven senescence depends on autophagy
  16. 556
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    FAP senescence: a critical event in muscle regeneration
  17. 557
    “…Senescent cell accumulation has been observed in age-associated diseases including cardiovascular diseases. …”
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    Senescent Cells: A Therapeutic Target in Cardiovascular Diseases
  18. 558
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    The senescence-associated secretory phenotype induces neuroendocrine transdifferentiation
  19. 559
    “…We developed an educational intervention that included a senescence simulator and assessed its impact on perception and attitudes in healthcare students. …”
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    The Role of an Exoskeleton Simulation of Senescence in Health Sciences Education
  20. 560
    “…Although it has been shown that cardiac fibroblasts become senescent in response to heart injury, it is unknown how the senescence of cardiac fibroblasts is regulated in vivo. …”
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    Induction of Senescence by Loss of Gata4 in Cardiac Fibroblasts
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