Mostrando 1,101 - 1,120 Resultados de 16,559 Para Buscar '"senescal"', tiempo de consulta: 0.22s Limitar resultados
  1. 1101
    “…Colorectal cancer (CRC)-associated senescent fibroblasts may play a crucial role in tumor progression, but the mechanism remains unclear. …”
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  2. 1102
    “…Autophagy is at first reported to suppress MSC senescence by clearing injured cytoplasmic organelles and impaired macromolecules, yet recent investigations also showed that autophagy can promote MSC senescence by inducing the production of senescence-associated secretory proteins (SASP). …”
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  3. 1103
  4. 1104
    “…Age-related changes in multiple aspects of the adaptive immune response to influenza have been well-documented including a decline in antibody responses to influenza vaccination and changes in the cell-mediated response associated with immune senescence. This review will focus on T cell responses to influenza and influenza vaccination in older adults, and how increasing frailty or coexistence of multiple (≥2) chronic conditions contributes to the loss of vaccine effectiveness for the prevention of hospitalization. …”
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  5. 1105
    por Vernot, Jean Paul
    Publicado 2020
    “…In particular, cellular senescence and senescence-associated soluble factors have been shown to unveil stem-like cell properties and cell plasticity. …”
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  6. 1106
    “…This review examines the available data on the impact of HIV and ART on immune and biological senescence of HIV-infected children.…”
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  7. 1107
    “…Hypoxia/reoxygenation (H/R) may play an important role via senescence in the mechanism of osteoarthritis (OA) development. …”
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  8. 1108
  9. 1109
    “…Rats were euthanized and brains were collected at 24 h, 1 month and 1 year post-blast to determine senescence-associated-β-galactosidase (SA-β-gal) activity in the cells using senescence marker stain. …”
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  10. 1110
  11. 1111
    “…Cellular senescence refers to a cellular phenotype characterized by an altered transcriptome, pro-inflammatory secretome, and generally irreversible growth arrest. …”
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  12. 1112
    por Zhou, Xueke, Hong, Yimei, Zhang, Hao, Li, Xin
    Publicado 2020
    “…Despite great advances in knowledge, the potential mechanisms underlying MSC senescence are not entirely clear. Understanding the molecular mechanisms that contribute to MSC senescence is crucial when exploring novel strategies to rejuvenate senescent MSCs. …”
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  13. 1113
  14. 1114
  15. 1115
    por Wu, Qi, Li, Bei, Liu, Le, Sun, Shengrong, Sun, Si
    Publicado 2020
    “…Centrosome aberrations are hallmarks of human cancers and contribute to the senescence process. Structural and numerical centrosome abnormalities trigger mitotic errors, cellular senescence, cell death, genomic instability and/or aneuploidy, resulting in human disorders such as aging and cancer and affecting immunity. …”
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  16. 1116
  17. 1117
    “…Human monocytic THP-1 cells (ATCC TIB-202) treated with D-galactose to induce cellular senescence were susceptible to DENV infection. These senescent cells showed increased viral entry/binding, gene/protein expression, and dsRNA replication. …”
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  18. 1118
    “…These mechanisms can be classified into gene and mitochondrial dysfunctions, intrinsic senescence processes, protein imbalance and alterations in stem cells. …”
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  19. 1119
  20. 1120
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