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  1. 1181
    “…Therefore, Gin A promotes antiproliferation and senescence of breast cancer cells induced by oxidative stress.…”
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    Gingerenone A Induces Antiproliferation and Senescence of Breast Cancer Cells
  2. 1182
    por Bahry, David
    Publicado 2022
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    Senescence, trait parameterization and (st)age-specific forces of selection
  3. 1183
    “…Cellular senescence and inflammation are interconnected causes and consequences of tissue aging. …”
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    Cell Senescence as a Mediator of Age-Dependent Brain Inflammation
  4. 1184
    “…CONCLUSION: Caloric restriction shapes the gut microbiome which can improve metabolic health and may induce a shift towards the naïve T and B cell compartment and, thus, delay immune senescence. Understanding the role of the gut microbiome as mediator of beneficial effects of low calorie diets on inflammation and metabolism may enhance the development of new therapeutic treatment options for metabolic diseases. …”
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    Effects of caloric restriction on the gut microbiome are linked with immune senescence
  5. 1185
    “…We showed that ZNF768 depletion impairs cell cycle progression and triggers cellular senescence, while its overexpression allows cells to bypass oncogene-induced senescence. …”
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    ZNF768: controlling cellular senescence and proliferation with ten fingers
  6. 1186
    por Cho, Sung Il, Jo, Eu-Ri, Song, Hansoo
    Publicado 2022
    “…This study was aimed at investigating the effect of the mitophagy activator, UA, on premature senescent auditory cells. The levels of cellular senescence-associated p53 and p21 significantly increased in H(2)O(2)-induced senescent House Ear Institute‐Organ of Corti 1 (HEI-OC1) cells and cochlear explants. …”
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    Urolithin A attenuates auditory cell senescence by activating mitophagy
  7. 1187
    “…The number of neurons was lower in senescent rats than in young adult rats (p < 0.05), but the soma size was larger than in young adult rats. …”
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    Intrinsic innervation of the ovary and its variations in the rat senescence process
  8. 1188
    “…Ethylene is one of the key senescence related hormones, but the underlying molecular mechanism of ethylene-induced leaf senescence remains poorly understood. …”
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    Overexpression of AHL9 accelerates leaf senescence in Arabidopsis thaliana
  9. 1189
    “…Chemotherapy-induced immunogenic senescence was demonstrated using a multi-marker, three-step workflow, and RNA-sequencing data. …”
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    Immunogenic senescence sensitizes lung cancer to LUNX-targeting therapy
  10. 1190
    “…Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease, and its occurrence and development are mediated by cellular senescence. Drugs targeting senescent cells seem like a promising and efficacious strategy for IPF treatment. …”
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    Pentoxifylline Inhibits Pulmonary Fibrosis by Regulating Cellular Senescence in Mice
  11. 1191
    “…Unfortunately, recurrence is inevitable and may be driven by surviving tumor cells eventually escaping senescence. A growing number of so-called “senolytic” drugs have been recently identified that are defined by their ability to selectively eliminate senescent cells. …”
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    Selective Vulnerability of Senescent Glioblastoma Cells to BCL-XL Inhibition
  12. 1192
    “…Our study aimed to explore the effect of cellular senescence and to find potential therapeutic strategies for gastric cancer. …”
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    Cellular Senescence-Related Genes: Predicting Prognosis in Gastric Cancer
  13. 1193
    “…We discuss the currently available ultrasound approaches and how studies in senescent mice are relevant for AD and can accelerate the application of low-intensity ultrasound in the clinic.…”
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    Ultrasound-Mediated Bioeffects in Senescent Mice and Alzheimer’s Mouse Models
  14. 1194
    “…BACKGROUND & AIMS: Cellular senescence frequently is present in injured livers. …”
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    Senescence Connects Autophagy Deficiency to Inflammation and Tumor Progression in the Liver
  15. 1195
    “…One major mechanism driving this accelerated aging is cellular senescence; cancer treatments induce cellular senescence in tumor cells and in normal, nontumor tissue, thereby helping mediate the onset of several chronic diseases. …”
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    The Achilles’ heel of cancer survivors: fundamentals of accelerated cellular senescence
  16. 1196
    por Huang, Peixin, Li, Zhonghai, Guo, Hongwei
    Publicado 2022
    “…Leaf senescence is controlled by a sophisticated genetic network that has been revealed through the study of the molecular mechanisms of hundreds of senescence-associated genes (SAGs), which are involved in multiple layers of regulation. …”
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    New Advances in the Regulation of Leaf Senescence by Classical and Peptide Hormones
  17. 1197
    “…RNA sequencing analysis revealed that distinct sets of genes were up‐ or down‐regulated during their lifetime, thus allowing to identify druggable gene networks and off‐the‐shelf compounds potentially dealing with epithelial stem cell senescence. These data will expand our knowledge on the genetic bases of senescence and potentially pave the way to the pharmacological modulation of ageing in epithelial stem cells.…”
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    Analysis and pharmacological modulation of senescence in human epithelial stem cells
  18. 1198
    “…IE leaves senesced sooner even in decapitated poplars where source–sink relationships and hormone homeostasis were perturbed. …”
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    Isoprene enhances leaf cytokinin metabolism and induces early senescence
  19. 1199
    “…Senescence appears to be closely interlinked with changes in cell metabolism. …”
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    Oxidative Glucose Metabolism Promotes Senescence in Vascular Endothelial Cells
  20. 1200
    “…In this context, cellular stress and inflammatory responses elicited by T. cruzi induce fibroblast and other immune cell senescence phenotypes that may compromise the host’s capacity to control the magnitude of T. cruzi-induced inflammation, contributing to parasite persistence and CD progression. …”
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    Cellular Stress and Senescence Induction during Trypanosoma cruzi Infection
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