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  1. 1281
    “…Ultraviolet radiation-induced premature senescence was also blocked by WWOX knockdown in human HEK293T cells. …”
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    Loss of fragile WWOX gene leads to senescence escape and genome instability
  2. 1282
    “…The gradual accumulation and inadequate renewal of senescent cells over time drive organismal aging. Senescent cells undergo altered gene expression and release inflammatory mediators collectively termed the senescence-associated secretory phenotype (SASP), which significantly contributes to a spectrum of age-related disorders, including cancer. …”
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    Aging and oral squamous cell carcinoma development: the role of cellular senescence
  3. 1283
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    Proteomics and β-hydroxybutyrylation Modification Characterization in the Hearts of Naturally Senescent Mice
  4. 1284
    “…Here, we demonstrated that AI image translation algorithms can effectively predict immunofluorescence images of MSC senescence markers from phase contrast images. We showed that the expression level of senescence markers including senescence-associated beta-galactosidase (SABG), p16, p21, and p38 are accurately predicted by deep-learning models for Doxorubicin-induced MSC senescence, irradiation-induced MSC senescence, and replicative MSC senescence. …”
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    Phenotyping senescent mesenchymal stromal cells using AI image translation
  5. 1285
    “…Such complex prevents the senescence induced by oxidative stress in C2C12 cells, as disruption of the androgen receptor/filamin A complex by Rh-2025u stapled peptide re-establishes the senescent phenotype in C2C12 cells. …”
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    Filamin A cooperates with the androgen receptor in preventing skeletal muscle senescence
  6. 1286
    “…In this study, we therefore compared cellular senescence markers and expression of respective genes between lung fibroblasts from patients with emphysema and control patients without COPD. …”
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    Lung fibroblasts from patients with emphysema show markers of senescence in vitro
  7. 1287
    “…RESULTS: Acting through ataxia telangiectasia mutated (ATM) and its downstream effectors, T-oligos induced apoptosis and senescence of MCF-7 cells but not NME cells, in which these signaling pathways were induced to a far lesser extent. …”
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    Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells
  8. 1288
    por Pearce, Louise, Brown, Wade H.
    Publicado 1960
    “…The acute form of hereditary premature senescence in 79 rabbits, among which the 20th generation of the condition was represented, has been described. …”
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    HEREDITARY PREMATURE SENESCENCE OF THE RABBIT : II. ACUTE FORM; GENERAL FEATURES
  9. 1289
    por Pearce, Louise, Brown, Wade H.
    Publicado 1960
    “…The occurrence of hereditary premature senescence in a family of pure bred Belgian hares belonging to a rabbit-breeding colony organized for the investigation of constitutional problems, has been described. …”
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    HEREDITARY PREMATURE SENESCENCE OF THE RABBIT : I. CHRONIC FORM; GENERAL FEATURES
  10. 1290
    “…Since the exponential law is the same as the law of monomolecular change in chemistry, and since the course of egg production with age may be taken as an index of the course of senescence of organs, or tissues limiting egg production, it is suggested that this exponential law of egg production substantiates the idea that senescence is a physicochemical process the course of which is limited by a chemical reaction. …”
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    THE RATE OF SENESCENCE OF THE DOMESTIC FOWL AS MEASURED BY THE DECLINE IN EGG PRODUCTION WITH AGE
  11. 1291
    “…Cellular senescence is the ultimate and irreversible loss of replicative capacity occurring in primary somatic cell culture. …”
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    DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?
  12. 1292
    “…The best-known form of human cell senescence is attributed to telomere shortening and a DNA-damage response through p53 and p21. …”
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    Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
  13. 1293
    “…Our studies indicate that replicative senescence of MSC preparations is a continuous process starting from the first passage onwards. …”
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    Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process
  14. 1294
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    The role of menopause and reproductive senescence in a long-lived social mammal
  15. 1295
    “…One issue is how to reconcile natural selection, which is understood as a process that purges deleterious characteristics, with senescence, which seems to offer no advantages to the individual. …”
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    Aging is not Senescence: A Short Computer Demonstration and Implications for Medical Practice
  16. 1296
    “…Soy isoflavones may have applications in cancer prevention and anti-inflammation, therefore this study was conducted to investigate the effect of dietary supplementation with black soybean on the immune response in the senescence-accelerated-prone mice (SAMP8) and -resistant mice (SAMPR1, as controls). …”
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    Nanonized black soybean enhances immune response in senescence-accelerated mice
  17. 1297
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    Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids
  18. 1298
    “…PURPOSE: To determine the levels of kynurenine (KN) and its metabolic precursor tryptophan (Trp) in lenses of accelerated-senescence OXYS (cataract model) and Wistar (control) rats at ages from 1 day to 24 months. …”
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    Tryptophan and kynurenine levels in lenses of Wistar and accelerated-senescence OXYS rats
  19. 1299
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    TobEA: an atlas of tobacco gene expression from seed to senescence
  20. 1300
    “…Salmonella invasion increased in nonphagocytotic senescent host cells in which caveolin-1 was also increased. …”
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    Caveolae-mediated entry of Salmonella typhimurium into senescent nonphagocytotic host cells
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