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  1. 1561
    “…The EPCs were then marked by CD62E/CD41 and senescence β-galactosidase assay using FACS. Identification of senescence cells was based on fluorescence with DAPI. …”
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    Differences in senescence of late Endothelial Progenitor Cells in non-smokers and smokers
  2. 1562
    “…Cellular senescence is a process that can prevent tumour development in a cell autonomous manner by imposing a stable cell cycle arrest after oncogene activation. …”
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    Adamantinomatous craniopharyngioma as a model to understand paracrine and senescence-induced tumourigenesis
  3. 1563
    “…Based on previous studies suggesting immune senescence in DS, we hypothesized that induction of cellular senescence may contribute to early thymic involution and immune dysregulation. …”
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    Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients
  4. 1564
    “…However, only two of the genes (MYOCD and ODZ2) demonstrated a significant correlation with MPC senescence in vitro. Our study provides new gene markers for predicting replicative senescence and the available quantity of MPCs but may also help to guide the development of new standard criteria for manufacturing.…”
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    Identification of Putative Markers That Predict the In Vitro Senescence of Mesenchymal Progenitor Cells
  5. 1565
    “…Senescence is the final stage of leaf development and is critical for plants’ fitness as nutrient relocation from leaves to reproductive organs takes place. …”
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    Integrative Modelling of Gene Expression and Digital Phenotypes to Describe Senescence in Wheat
  6. 1566
    “…Potential therapeutic interventions targeting cell senescence and regulatory mechanisms, using state-of-the-art techniques are also discussed.…”
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    Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention
  7. 1567
    “…Focusing on brain senescence, we examine correlates and consequences of aging across two divergent eusocial clades and how they differ from solitary taxa. …”
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    Eusociality and Senescence: Neuroprotection and Physiological Resilience to Aging in Insect and Mammalian Systems
  8. 1568
    “…Cardiac senescence is associated with cardiomyopathy which is a degenerative disease in the aging process of the elderly. …”
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    Cardiac senescence is alleviated by the natural flavone acacetin via enhancing mitophagy
  9. 1569
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    Enhanced stress-induced senescence-response may increase species lifespan
  10. 1570
    “…We hypothesize that aberrant ECM deposition augments fibroblast senescence, creating a perpetuating cycle favouring disease progression. …”
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    Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM
  11. 1571
    “…Menopause, probably the most important natural change in a woman’s life and a major component of female senescence, is characterized, inter alia, by cessation of ovarian estrogen and progesterone production, resulting in a gradual deterioration of the female immune system. …”
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    Effects of Hormone Therapy and Flavonoids Capable on Reversal of Menopausal Immune Senescence
  12. 1572
    por Fessler, Johannes, Angiari, Stefano
    Publicado 2021
    “…In particular, the presence of senescent T lymphocytes has been reported in neurological diseases, with some works pointing towards a direct connection between T cell senescence, inflammation and neuronal damage. …”
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    The Role of T Cell Senescence in Neurological Diseases and Its Regulation by Cellular Metabolism
  13. 1573
    “…Cellular senescence is a form of proliferative arrest triggered in response to a wide variety of stimuli and characterized by unique changes in cell morphology and function. …”
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    mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership
  14. 1574
    “…Furthermore, we found an increase in the levels of SA-β-galactosidase, a specific marker of cellular senescence. Together, these findings support an association between chronological age and MSC senescence. …”
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    Chronological Age Affects MSC Senescence In Vitro—A Systematic Review
  15. 1575
    “…In this study, we investigate the expression and the role of HDACs on the senescent phenotype of dermal fibroblasts. We report that during replicative senescence, most canonical HDACs are less expressed. …”
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    HDAC2 and 7 down-regulation induces senescence in dermal fibroblasts
  16. 1576
    “…Leaf senescence is important for crop yield as delaying it can increase the average yield. …”
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    Potential interaction between autophagy and auxin during maize leaf senescence
  17. 1577
    por Saito, Yuki, Chikenji, Takako S.
    Publicado 2021
    “…However, aging, chronic inflammatory diseases, sarcopenia, and neuromuscular disorders cause muscle loss and degeneration, resulting in muscular dysfunction. Cellular senescence, a state of irreversible cell cycle arrest, acts during normal embryonic development and remodeling after tissue damage; when these processes are complete, the senescent cells are eliminated. …”
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    Diverse Roles of Cellular Senescence in Skeletal Muscle Inflammation, Regeneration, and Therapeutics
  18. 1578
    “…Therapy-induced senescence (TIS) is a major cellular response to anticancer therapies. …”
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    Glutamine promotes escape from therapy-induced senescence in tumor cells
  19. 1579
    “…RUT exerted a senescence-inducing property highlighted by the elevated expression of senescent-associated beta-galactosidase (SA-β-gal) in SK-MEL-28 cells. …”
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    Rutin Exerts Cytotoxic and Senescence-Inducing Properties in Human Melanoma Cells
  20. 1580
    “…During aging, brain performances decline. Cellular senescence is one of the aging drivers and a key feature of a variety of human age‐related disorders. …”
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    REST/NRSF deficiency impairs autophagy and leads to cellular senescence in neurons
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